2,2'-((1R,3R,4S)-4-methyl-4-vinylcyclohexane-1,3-diyl) bis(prop-2-en-1-amine), a bisamino derivative of β-Elemene, inhibits glioblastoma growth through downregulation of YAP signaling

β-Elemene, a compound extracted from Chinese herb , has been demonstrated with antitumor effects in various cancers, including glioblastoma (GBM), a primary brain tumor with high morbidity and mortality. In this study, we reported a bisamino derivative of β-Elemene, 2, 2'-((1R, 3R, 4S)-4-methyl...

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Veröffentlicht in:American journal of cancer research 2022, Vol.12 (12), p.5484-5499
Hauptverfasser: Cao, Li-Ying, Xu, Jia-Yun, Zhuo, Xiao-Tao, Zhang, Wei, Wei, Li-Jia, Dong, Jian-Hong, Bai, Ren-Ren, Wang, Xin, Jiang, Yuan-Yuan, Wang, Yong-Jie, Ye, Xiang-Yang, Xie, Tian, Huang, Zhi-Hui
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Sprache:eng
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