Decreased Expression of EZH2 in Granulosa Cells Contributes to Endometriosis-Associated Infertility by Targeting IL-1R2

Abstract The mechanism by which endometriosis, a common gynecological disease characterized by chronic pelvic pain and infertility, causes infertility remains elusive. Luteinized unruptured follicle syndrome, the most common type of ovulatory dysfunction, is a cause of endometriosis-associated infer...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2023-02, Vol.164 (2), p.1
Hauptverfasser:	Lin, Xiang, Tong, Xiaomei, Zhang, Yinli, Gu, Weijia, Huang, Qianmeng, Zhang, Yi, Zhuo, Feng, Zhao, Fanxuan, Jin, Xiaoying, Li, Chao, Huang, Dong, Zhang, Songying, Dai, Yongdong
Format:	Artikel
Sprache:	eng
Schlagworte:	Amplification Animals CCAAT/enhancer-binding protein Chromatin Endocrinology Endometriosis Endometriosis - complications Endometriosis - genetics Endometriosis - metabolism Enhancer of Zeste Homolog 2 Protein - metabolism Enzyme-linked immunosorbent assay Enzymes Estradiol Female Fertility Follicles Follicular fluid Gametocytes Gene expression Genes Genomics Glycoproteins Gonadotropin Granulosa cells Granulosa Cells - metabolism Growth factors Gynecological diseases Histones - metabolism Hormones Humans IL-1β Infertility Infertility, Female - genetics Infertility, Female - metabolism Inflammation Interleukin 1 receptors Interleukins Kinases Luteinizing hormone Mice Microenvironments Oocytes Ovaries Ovulation Oxidative stress Paracrine signalling Phosphates Prostaglandins E Protein binding Protein kinases Receptors Receptors, Interleukin-1 Type II - genetics Receptors, Interleukin-1 Type II - metabolism RNA RNA sequencing
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