Surface electrostatics dictate RNA-binding protein CAPRIN1 condensate concentration and hydrodynamic properties

Biomolecular condensates concentrate proteins, nucleic acids, and small molecules and play an essential role in many biological processes. Their formation is tuned by a balance between energetically favorable and unfavorable contacts, with charge–charge interactions playing a central role in some sy...

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Veröffentlicht in:	The Journal of biological chemistry 2023-01, Vol.299 (1), p.102776-102776, Article 102776
Hauptverfasser:	Toyama, Yuki, Rangadurai, Atul Kaushik, Forman-Kay, Julie D., Kay, Lewis E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate biomolecular condensates electrostatics Hydrodynamics intrinsically disordered protein Intrinsically Disordered Proteins - chemistry NMR phase separation RNA-Binding Proteins - chemistry Sodium Chloride - metabolism Static Electricity
Online-Zugang:	Volltext
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