Single-cell profiling identifies ACE + granuloma macrophages as a nonpermissive niche for intracellular bacteria during persistent Salmonella infection

Macrophages mediate key antimicrobial responses against intracellular bacterial pathogens, such as . Yet, they can also act as a permissive niche for these pathogens to persist in infected tissues within granulomas, which are immunological structures composed of macrophages and other immune cells. W...

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Veröffentlicht in:	Science advances 2023-01, Vol.9 (1), p.eadd4333-eadd4333
Hauptverfasser:	Pham, Trung H M, Xue, Yuan, Brewer, Susan M, Bernstein, Kenneth E, Quake, Stephen R, Monack, Denise M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedicine and Life Sciences Granuloma Immunology Macrophages - microbiology Mice Microbiology Persistent Infection Salmonella Infections - genetics Salmonella typhimurium - genetics SciAdv r-articles
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