Fusobacterium Nucleatum-Induced Tumor Mutation Burden Predicts Poor Survival of Gastric Cancer Patients

Co-infection of and is a microbial biomarker for poor prognosis of gastric cancer patients. is associated with microsatellite instability and the accumulation of mutations in colorectal cancer. Here, we investigated the mutation landscape of -positive resected gastric cancer tissues using Illumina T...

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Veröffentlicht in:	Cancers 2022-12, Vol.15 (1), p.269
Hauptverfasser:	Hsieh, Yung-Yu, Kuo, Wen-Lin, Hsu, Wan-Ting, Tung, Shui-Yi, Li, Chin
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein Biomarkers Capillary electrophoresis Cell cycle Colorectal cancer Colorectal carcinoma Copy number DNA damage ErbB-2 protein ErbB-3 protein Fibroblast growth factors Fusobacterium nucleatum Gastric cancer Gastrointestinal tract Gene amplification Genetic aspects Genomes Gram-negative bacteria Health aspects Helicobacter pylori Infections Medical prognosis Microbiota Microsatellite instability Mutation Mutation (Biology) Oncology p53 Protein Prognosis Review boards Risk factors Statistical analysis Stomach cancer TOR protein Transcription activation Tumors
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