Short and Long-Term Surgical Outcomes of Laparoscopic Total Gastrectomy Compared with Open Total Gastrectomy in Gastric Cancer Patients
This study aimed to compare the efficacy of laparoscopic total gastrectomy (LTG) with that of open total gastrectomy (OTG) in terms of postoperative complications and long-term survival. We retrospectively reviewed the clinicopathological data of 560 patients, who underwent total gastrectomy between...
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| Veröffentlicht in: | Cancers 2022-12, Vol.15 (1), p.76 |
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| creator | Eom, Sang Soo Park, Sin Hye Eom, Bang Wool Yoon, Hong Man Kim, Young-Woo Ryu, Keun Won |
| description | This study aimed to compare the efficacy of laparoscopic total gastrectomy (LTG) with that of open total gastrectomy (OTG) in terms of postoperative complications and long-term survival. We retrospectively reviewed the clinicopathological data of 560 patients, who underwent total gastrectomy between 2012 and 2016 at the National Cancer Center, Korea. Propensity-score matching (PSM) was performed to correct for discrepancies between the two groups. Matched variables included sex, age, body mass index, American Society of Anesthesiologists score, and pathological Tumor-Node-Metastasis stage. After PSM, 238 patients were included in this analysis. The rate of D2 lymph node dissection was significantly higher in the OTG group than in the LTG group. The estimated blood loss was significantly lower in the LTG group than in the OTG group. The overall complication rate was not significantly different between the two groups. There was no significant difference in the 3-year disease-free and 5-year overall survival rates between the two groups. LTG and OTG had comparable efficacies in gastric cancer patients regarding short- and long-term surgical outcomes. This study suggests that LTG could be an alternative approach to the OTG. |
| doi_str_mv | 10.3390/cancers15010076 |
| format | Article |
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We retrospectively reviewed the clinicopathological data of 560 patients, who underwent total gastrectomy between 2012 and 2016 at the National Cancer Center, Korea. Propensity-score matching (PSM) was performed to correct for discrepancies between the two groups. Matched variables included sex, age, body mass index, American Society of Anesthesiologists score, and pathological Tumor-Node-Metastasis stage. After PSM, 238 patients were included in this analysis. The rate of D2 lymph node dissection was significantly higher in the OTG group than in the LTG group. The estimated blood loss was significantly lower in the LTG group than in the OTG group. The overall complication rate was not significantly different between the two groups. There was no significant difference in the 3-year disease-free and 5-year overall survival rates between the two groups. LTG and OTG had comparable efficacies in gastric cancer patients regarding short- and long-term surgical outcomes. This study suggests that LTG could be an alternative approach to the OTG.</description><identifier>ISSN: 2072-6694</identifier><identifier>EISSN: 2072-6694</identifier><identifier>DOI: 10.3390/cancers15010076</identifier><identifier>PMID: 36612073</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Body mass index ; Cancer therapies ; Care and treatment ; Chemotherapy ; Complications ; Gastrectomy ; Gastric cancer ; Gastrointestinal surgery ; Histology ; Laparoscopic surgery ; Laparoscopy ; Lymph nodes ; Lymphatic system ; Metastases ; Methods ; Mortality ; Patient outcomes ; Postoperative ; Stomach cancer ; Surgical outcomes ; Survival ; Survival analysis ; Tumors</subject><ispartof>Cancers, 2022-12, Vol.15 (1), p.76</ispartof><rights>COPYRIGHT 2022 MDPI AG</rights><rights>2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2022 by the authors. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c488t-d0c11e1e1461c5f5d9fae597a91ccf25c489d5e809549cc86574bd20edecf50b3</citedby><cites>FETCH-LOGICAL-c488t-d0c11e1e1461c5f5d9fae597a91ccf25c489d5e809549cc86574bd20edecf50b3</cites><orcidid>0000-0002-6252-7532</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817857/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817857/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36612073$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Eom, Sang Soo</creatorcontrib><creatorcontrib>Park, Sin Hye</creatorcontrib><creatorcontrib>Eom, Bang Wool</creatorcontrib><creatorcontrib>Yoon, Hong Man</creatorcontrib><creatorcontrib>Kim, Young-Woo</creatorcontrib><creatorcontrib>Ryu, Keun Won</creatorcontrib><title>Short and Long-Term Surgical Outcomes of Laparoscopic Total Gastrectomy Compared with Open Total Gastrectomy in Gastric Cancer Patients</title><title>Cancers</title><addtitle>Cancers (Basel)</addtitle><description>This study aimed to compare the efficacy of laparoscopic total gastrectomy (LTG) with that of open total gastrectomy (OTG) in terms of postoperative complications and long-term survival. 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This study suggests that LTG could be an alternative approach to the OTG.</description><subject>Body mass index</subject><subject>Cancer therapies</subject><subject>Care and treatment</subject><subject>Chemotherapy</subject><subject>Complications</subject><subject>Gastrectomy</subject><subject>Gastric cancer</subject><subject>Gastrointestinal surgery</subject><subject>Histology</subject><subject>Laparoscopic surgery</subject><subject>Laparoscopy</subject><subject>Lymph nodes</subject><subject>Lymphatic system</subject><subject>Metastases</subject><subject>Methods</subject><subject>Mortality</subject><subject>Patient outcomes</subject><subject>Postoperative</subject><subject>Stomach cancer</subject><subject>Surgical outcomes</subject><subject>Survival</subject><subject>Survival analysis</subject><subject>Tumors</subject><issn>2072-6694</issn><issn>2072-6694</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkk1P3DAQhqOqVUGUc2-VpV56CdhJbMeXSmjVQqWVthLbs-WdTHaNEju1HSp-Qf82hqUUEJ6DP-aZdzz2FMVHRk_qWtFTMA4wRMYpo1SKN8VhRWVVCqGat0_WB8VxjFc0j7pmUsj3xUEtBMv--rD4e7nzIRHjOrL0bluuMYzkcg5bC2YgqzmBHzES35OlmUzwEfxkgax9yu5zE1NASH68IQs_Zj925I9NO7Ka0L0CWbffZoXF_eXJT5MsuhQ_FO96M0Q8fpiPil_fv60XF-Vydf5jcbYsoWnbVHYUGMNsjWDAe96p3iBX0igG0Fc8U6rj2FLFGwXQCi6bTVdR7BB6Tjf1UfF1rzvNmxE7yLmDGfQU7GjCjfbG6uceZ3d666-1aplsucwCXx4Egv89Y0x6tBFwGIxDP0ddScGUlC1jGf38Ar3yc3C5vHuKqpY34j-1NQNq63qf88KdqD6TDa9kXbVNpk5eobJ1OFrwDnubz58FnO4DIH9aDNg_1siovmsf_aJ9csSnp0_zyP9rlvoWKovDCQ</recordid><startdate>20221223</startdate><enddate>20221223</enddate><creator>Eom, Sang Soo</creator><creator>Park, Sin Hye</creator><creator>Eom, Bang Wool</creator><creator>Yoon, Hong Man</creator><creator>Kim, Young-Woo</creator><creator>Ryu, Keun Won</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T5</scope><scope>7TO</scope><scope>7XB</scope><scope>8FE</scope><scope>8FH</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-6252-7532</orcidid></search><sort><creationdate>20221223</creationdate><title>Short and Long-Term Surgical Outcomes of Laparoscopic Total Gastrectomy Compared with Open Total Gastrectomy in Gastric Cancer Patients</title><author>Eom, Sang Soo ; Park, Sin Hye ; Eom, Bang Wool ; Yoon, Hong Man ; Kim, Young-Woo ; Ryu, Keun Won</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c488t-d0c11e1e1461c5f5d9fae597a91ccf25c489d5e809549cc86574bd20edecf50b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Body mass index</topic><topic>Cancer therapies</topic><topic>Care and treatment</topic><topic>Chemotherapy</topic><topic>Complications</topic><topic>Gastrectomy</topic><topic>Gastric cancer</topic><topic>Gastrointestinal surgery</topic><topic>Histology</topic><topic>Laparoscopic surgery</topic><topic>Laparoscopy</topic><topic>Lymph nodes</topic><topic>Lymphatic system</topic><topic>Metastases</topic><topic>Methods</topic><topic>Mortality</topic><topic>Patient outcomes</topic><topic>Postoperative</topic><topic>Stomach cancer</topic><topic>Surgical outcomes</topic><topic>Survival</topic><topic>Survival analysis</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Eom, Sang Soo</creatorcontrib><creatorcontrib>Park, Sin Hye</creatorcontrib><creatorcontrib>Eom, Bang Wool</creatorcontrib><creatorcontrib>Yoon, Hong Man</creatorcontrib><creatorcontrib>Kim, Young-Woo</creatorcontrib><creatorcontrib>Ryu, Keun Won</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Cancers</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Eom, Sang Soo</au><au>Park, Sin Hye</au><au>Eom, Bang Wool</au><au>Yoon, Hong Man</au><au>Kim, Young-Woo</au><au>Ryu, Keun Won</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Short and Long-Term Surgical Outcomes of Laparoscopic Total Gastrectomy Compared with Open Total Gastrectomy in Gastric Cancer Patients</atitle><jtitle>Cancers</jtitle><addtitle>Cancers (Basel)</addtitle><date>2022-12-23</date><risdate>2022</risdate><volume>15</volume><issue>1</issue><spage>76</spage><pages>76-</pages><issn>2072-6694</issn><eissn>2072-6694</eissn><abstract>This study aimed to compare the efficacy of laparoscopic total gastrectomy (LTG) with that of open total gastrectomy (OTG) in terms of postoperative complications and long-term survival. 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This study suggests that LTG could be an alternative approach to the OTG.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>36612073</pmid><doi>10.3390/cancers15010076</doi><orcidid>https://orcid.org/0000-0002-6252-7532</orcidid><oa>free_for_read</oa></addata></record> |
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| source | MDPI - Multidisciplinary Digital Publishing Institute; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; PubMed Central Open Access |
| subjects | Body mass index Cancer therapies Care and treatment Chemotherapy Complications Gastrectomy Gastric cancer Gastrointestinal surgery Histology Laparoscopic surgery Laparoscopy Lymph nodes Lymphatic system Metastases Methods Mortality Patient outcomes Postoperative Stomach cancer Surgical outcomes Survival Survival analysis Tumors |
| title | Short and Long-Term Surgical Outcomes of Laparoscopic Total Gastrectomy Compared with Open Total Gastrectomy in Gastric Cancer Patients |
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