SNAP23 is essential for germination of EV-D68 replication organelles

Picornaviruses rearrange host cell membranes to facilitate their own replication. Here we investigate the Qbc SNARE, SNAP23, which is found at the plasma membrane and plays roles in exocytosis. We found that knockdown of SNAP23 expression inhibits virus replication but not release from cells. Knocki...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2023-01, Vol.578, p.117-127
Hauptverfasser:	Miller, Katelyn, Wagner, Michael A., Jassey, Alagie, Jackson, William T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line Cell Membrane - metabolism Enterovirus D, Human - genetics EV-D68 Membrane Fusion Organelles Picornavirus SNAP23 SNARE Virus Replication
Online-Zugang:	Volltext
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