Linking graphene-based material physicochemical properties with molecular adsorption, structure and cell fate
Graphene, an allotrope of carbon, consists of a single layer of carbon atoms with uniquely tuneable properties. As such, graphene-based materials (GBMs) have gained interest for tissue engineering applications. GBMs are often discussed in the context of how different physicochemical properties affec...
Gespeichert in:
| Veröffentlicht in: | Communications chemistry 2020-01, Vol.3 (1), p.8, Article 8 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 1 |
| container_start_page | 8 |
| container_title | Communications chemistry |
| container_volume | 3 |
| creator | Kumar, Sachin Parekh, Sapun H. |
| description | Graphene, an allotrope of carbon, consists of a single layer of carbon atoms with uniquely tuneable properties. As such, graphene-based materials (GBMs) have gained interest for tissue engineering applications. GBMs are often discussed in the context of how different physicochemical properties affect cell physiology, without explicitly considering the impact of adsorbed proteins. Establishing a relationship between graphene properties, adsorbed proteins, and cell response is necessary as these proteins provide the surface upon which cells attach and grow. This review highlights the molecular adsorption of proteins on different GBMs, protein structural changes, and the connection to cellular function.
Graphene-based materials are widely studied in biomedical applications, but a full picture of their interactions with proteins and cells remains elusive. Here the molecular basis for the effect of graphene-based materials on cell fate and in tissue engineering is reviewed. |
| doi_str_mv | 10.1038/s42004-019-0254-9 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9814659</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2490400816</sourcerecordid><originalsourceid>FETCH-LOGICAL-c498t-e4537fe58af00ca762e7cc2c0b81b3649f489a2581d80a43c9522abdc51078e83</originalsourceid><addsrcrecordid>eNp9kc1u1TAQRiMEolXpA7BBltiwIDD-SWxvkFAFLdKV2MDacpzJvS6JHeykqG-Po1tKQYKVbc3xNzM6VfWcwhsKXL3NggGIGqiugTWi1o-qU8a1rnnb6scP7ifVec7XAMCAcinV0-qEtxI4B31aTTsfvvmwJ_tk5wMGrDubsSeTXTB5O5L5cJu9i-6Ak3fbO8UZ0-Ixkx9-OZApjujW0SZi-xzTvPgYXpO8pNUta0JiQ08cjiMZSuKz6slgx4znd-dZ9fXjhy8XV_Xu8-Wni_e72gmtlhpFw-WAjbIDgLOyZSidYw46RTveCj0IpS1rFO0VWMGdbhizXe8aClKh4mfVu2PuvHYT9g7Dkuxo5uQnm25NtN78WQn-YPbxxmhFRdvoEvDqLiDF7yvmxUw-b2vYgHHNhkkJlEqheUFf_oVexzWFsp5hQoMAULT9L1WkCKFKXKHokXIp5pxwuB-Zgtmsm6N1U6ybzbrZRn3xcNf7H78cF4AdgVxKYY_pd-t_p_4E72a5Dw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2377448117</pqid></control><display><type>article</type><title>Linking graphene-based material physicochemical properties with molecular adsorption, structure and cell fate</title><source>Nature Free</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>PubMed Central Open Access</source><source>Springer Nature OA Free Journals</source><creator>Kumar, Sachin ; Parekh, Sapun H.</creator><creatorcontrib>Kumar, Sachin ; Parekh, Sapun H.</creatorcontrib><description>Graphene, an allotrope of carbon, consists of a single layer of carbon atoms with uniquely tuneable properties. As such, graphene-based materials (GBMs) have gained interest for tissue engineering applications. GBMs are often discussed in the context of how different physicochemical properties affect cell physiology, without explicitly considering the impact of adsorbed proteins. Establishing a relationship between graphene properties, adsorbed proteins, and cell response is necessary as these proteins provide the surface upon which cells attach and grow. This review highlights the molecular adsorption of proteins on different GBMs, protein structural changes, and the connection to cellular function.
Graphene-based materials are widely studied in biomedical applications, but a full picture of their interactions with proteins and cells remains elusive. Here the molecular basis for the effect of graphene-based materials on cell fate and in tissue engineering is reviewed.</description><identifier>ISSN: 2399-3669</identifier><identifier>EISSN: 2399-3669</identifier><identifier>DOI: 10.1038/s42004-019-0254-9</identifier><identifier>PMID: 36703309</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>639/301/357/918 ; 639/301/54/1754 ; 639/301/54/2295 ; Adsorption ; Allotropy ; Biomedical materials ; Carbon ; Cellular structure ; Chemistry ; Chemistry and Materials Science ; Chemistry/Food Science ; Graphene ; Molecular structure ; Properties (attributes) ; Proteins ; Review ; Review Article ; Tissue engineering</subject><ispartof>Communications chemistry, 2020-01, Vol.3 (1), p.8, Article 8</ispartof><rights>The Author(s) 2020</rights><rights>2020. The Author(s).</rights><rights>This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2020. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c498t-e4537fe58af00ca762e7cc2c0b81b3649f489a2581d80a43c9522abdc51078e83</citedby><cites>FETCH-LOGICAL-c498t-e4537fe58af00ca762e7cc2c0b81b3649f489a2581d80a43c9522abdc51078e83</cites><orcidid>0000-0001-8522-1854</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814659/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814659/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27903,27904,41099,42168,51554,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36703309$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kumar, Sachin</creatorcontrib><creatorcontrib>Parekh, Sapun H.</creatorcontrib><title>Linking graphene-based material physicochemical properties with molecular adsorption, structure and cell fate</title><title>Communications chemistry</title><addtitle>Commun Chem</addtitle><addtitle>Commun Chem</addtitle><description>Graphene, an allotrope of carbon, consists of a single layer of carbon atoms with uniquely tuneable properties. As such, graphene-based materials (GBMs) have gained interest for tissue engineering applications. GBMs are often discussed in the context of how different physicochemical properties affect cell physiology, without explicitly considering the impact of adsorbed proteins. Establishing a relationship between graphene properties, adsorbed proteins, and cell response is necessary as these proteins provide the surface upon which cells attach and grow. This review highlights the molecular adsorption of proteins on different GBMs, protein structural changes, and the connection to cellular function.
Graphene-based materials are widely studied in biomedical applications, but a full picture of their interactions with proteins and cells remains elusive. Here the molecular basis for the effect of graphene-based materials on cell fate and in tissue engineering is reviewed.</description><subject>639/301/357/918</subject><subject>639/301/54/1754</subject><subject>639/301/54/2295</subject><subject>Adsorption</subject><subject>Allotropy</subject><subject>Biomedical materials</subject><subject>Carbon</subject><subject>Cellular structure</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Chemistry/Food Science</subject><subject>Graphene</subject><subject>Molecular structure</subject><subject>Properties (attributes)</subject><subject>Proteins</subject><subject>Review</subject><subject>Review Article</subject><subject>Tissue engineering</subject><issn>2399-3669</issn><issn>2399-3669</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kc1u1TAQRiMEolXpA7BBltiwIDD-SWxvkFAFLdKV2MDacpzJvS6JHeykqG-Po1tKQYKVbc3xNzM6VfWcwhsKXL3NggGIGqiugTWi1o-qU8a1rnnb6scP7ifVec7XAMCAcinV0-qEtxI4B31aTTsfvvmwJ_tk5wMGrDubsSeTXTB5O5L5cJu9i-6Ak3fbO8UZ0-Ixkx9-OZApjujW0SZi-xzTvPgYXpO8pNUta0JiQ08cjiMZSuKz6slgx4znd-dZ9fXjhy8XV_Xu8-Wni_e72gmtlhpFw-WAjbIDgLOyZSidYw46RTveCj0IpS1rFO0VWMGdbhizXe8aClKh4mfVu2PuvHYT9g7Dkuxo5uQnm25NtN78WQn-YPbxxmhFRdvoEvDqLiDF7yvmxUw-b2vYgHHNhkkJlEqheUFf_oVexzWFsp5hQoMAULT9L1WkCKFKXKHokXIp5pxwuB-Zgtmsm6N1U6ybzbrZRn3xcNf7H78cF4AdgVxKYY_pd-t_p_4E72a5Dw</recordid><startdate>20200120</startdate><enddate>20200120</enddate><creator>Kumar, Sachin</creator><creator>Parekh, Sapun H.</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>C6C</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FE</scope><scope>8FG</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>HCIFZ</scope><scope>KB.</scope><scope>L6V</scope><scope>M7S</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-8522-1854</orcidid></search><sort><creationdate>20200120</creationdate><title>Linking graphene-based material physicochemical properties with molecular adsorption, structure and cell fate</title><author>Kumar, Sachin ; Parekh, Sapun H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c498t-e4537fe58af00ca762e7cc2c0b81b3649f489a2581d80a43c9522abdc51078e83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>639/301/357/918</topic><topic>639/301/54/1754</topic><topic>639/301/54/2295</topic><topic>Adsorption</topic><topic>Allotropy</topic><topic>Biomedical materials</topic><topic>Carbon</topic><topic>Cellular structure</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Chemistry/Food Science</topic><topic>Graphene</topic><topic>Molecular structure</topic><topic>Properties (attributes)</topic><topic>Proteins</topic><topic>Review</topic><topic>Review Article</topic><topic>Tissue engineering</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kumar, Sachin</creatorcontrib><creatorcontrib>Parekh, Sapun H.</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>SciTech Premium Collection</collection><collection>Materials Science Database</collection><collection>ProQuest Engineering Collection</collection><collection>Engineering Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Communications chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kumar, Sachin</au><au>Parekh, Sapun H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Linking graphene-based material physicochemical properties with molecular adsorption, structure and cell fate</atitle><jtitle>Communications chemistry</jtitle><stitle>Commun Chem</stitle><addtitle>Commun Chem</addtitle><date>2020-01-20</date><risdate>2020</risdate><volume>3</volume><issue>1</issue><spage>8</spage><pages>8-</pages><artnum>8</artnum><issn>2399-3669</issn><eissn>2399-3669</eissn><abstract>Graphene, an allotrope of carbon, consists of a single layer of carbon atoms with uniquely tuneable properties. As such, graphene-based materials (GBMs) have gained interest for tissue engineering applications. GBMs are often discussed in the context of how different physicochemical properties affect cell physiology, without explicitly considering the impact of adsorbed proteins. Establishing a relationship between graphene properties, adsorbed proteins, and cell response is necessary as these proteins provide the surface upon which cells attach and grow. This review highlights the molecular adsorption of proteins on different GBMs, protein structural changes, and the connection to cellular function.
Graphene-based materials are widely studied in biomedical applications, but a full picture of their interactions with proteins and cells remains elusive. Here the molecular basis for the effect of graphene-based materials on cell fate and in tissue engineering is reviewed.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>36703309</pmid><doi>10.1038/s42004-019-0254-9</doi><orcidid>https://orcid.org/0000-0001-8522-1854</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2399-3669 |
| ispartof | Communications chemistry, 2020-01, Vol.3 (1), p.8, Article 8 |
| issn | 2399-3669 2399-3669 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9814659 |
| source | Nature Free; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; PubMed Central Open Access; Springer Nature OA Free Journals |
| subjects | 639/301/357/918 639/301/54/1754 639/301/54/2295 Adsorption Allotropy Biomedical materials Carbon Cellular structure Chemistry Chemistry and Materials Science Chemistry/Food Science Graphene Molecular structure Properties (attributes) Proteins Review Review Article Tissue engineering |
| title | Linking graphene-based material physicochemical properties with molecular adsorption, structure and cell fate |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T03%3A50%3A42IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Linking%20graphene-based%20material%20physicochemical%20properties%20with%20molecular%20adsorption,%20structure%20and%20cell%20fate&rft.jtitle=Communications%20chemistry&rft.au=Kumar,%20Sachin&rft.date=2020-01-20&rft.volume=3&rft.issue=1&rft.spage=8&rft.pages=8-&rft.artnum=8&rft.issn=2399-3669&rft.eissn=2399-3669&rft_id=info:doi/10.1038/s42004-019-0254-9&rft_dat=%3Cproquest_pubme%3E2490400816%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2377448117&rft_id=info:pmid/36703309&rfr_iscdi=true |