Assessment of adherence to statin therapy in patients with coronary artery disease: comparison of three self-reporting measures

ObjectivesTo investigate adherence to statin therapy using three self-reporting adherence measures in patients with coronary artery disease and to compare the three measures.MethodsA cross-sectional study was carried out at a multidisciplinary outpatient clinic of cardiology at a teaching hospital i...

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Veröffentlicht in:European journal of hospital pharmacy. Science and practice 2023-01, Vol.30 (1), p.24-28
Hauptverfasser: Camila de Souza Groia Veloso, Ronara, Cruzeiro, Maria Gabriela Martins, Dias, Bianca Menezes, Reis, Adriano Max Moreira
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container_issue 1
container_start_page 24
container_title European journal of hospital pharmacy. Science and practice
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creator Camila de Souza Groia Veloso, Ronara
Cruzeiro, Maria Gabriela Martins
Dias, Bianca Menezes
Reis, Adriano Max Moreira
description ObjectivesTo investigate adherence to statin therapy using three self-reporting adherence measures in patients with coronary artery disease and to compare the three measures.MethodsA cross-sectional study was carried out at a multidisciplinary outpatient clinic of cardiology at a teaching hospital in south-eastern Brazil in patients with coronary artery disease who were using statins. The sample consisted of 148 patients who were selected from April 2018 to February 2019. Adherence to statin therapy was determined by the Measure of Adherence to Treatment, Visual Analogue Scale of adherence and 7-day recall. A descriptive analysis and determination of the level of agreement between the adherence scales by the Cohen kappa coefficient were performed.ResultsThe study included 148 patients (104 (70.3%) men, median age 62 years) diagnosed with coronary artery disease who were using statins. The adherence to statin therapy was 98.6% using the Measure of Adherence to Treatment, 95.9% with the Visual Analogue Scale and 95.3% with 7-day recall. Agreement between the Measure of Adherence to Treatment and the Visual Analogue Scale (0.277) and the Measure of Adherence to Treatment and 7-day recall (0.241) was low. There was a high level of agreement between the Visual Analogue Scale and 7-day recall (0.759).ConclusionsThe adherence Visual Analogue Scale and 7-day recall were shown to be easy to apply, low-cost adherence measures to identify adherence to statins in patients with coronary artery disease. The Measure of Adherence to Treatment may also be used to provide information regarding the specific reasons for non-adherent behaviour.
doi_str_mv 10.1136/ejhpharm-2021-002725
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The sample consisted of 148 patients who were selected from April 2018 to February 2019. Adherence to statin therapy was determined by the Measure of Adherence to Treatment, Visual Analogue Scale of adherence and 7-day recall. A descriptive analysis and determination of the level of agreement between the adherence scales by the Cohen kappa coefficient were performed.ResultsThe study included 148 patients (104 (70.3%) men, median age 62 years) diagnosed with coronary artery disease who were using statins. The adherence to statin therapy was 98.6% using the Measure of Adherence to Treatment, 95.9% with the Visual Analogue Scale and 95.3% with 7-day recall. Agreement between the Measure of Adherence to Treatment and the Visual Analogue Scale (0.277) and the Measure of Adherence to Treatment and 7-day recall (0.241) was low. There was a high level of agreement between the Visual Analogue Scale and 7-day recall (0.759).ConclusionsThe adherence Visual Analogue Scale and 7-day recall were shown to be easy to apply, low-cost adherence measures to identify adherence to statins in patients with coronary artery disease. The Measure of Adherence to Treatment may also be used to provide information regarding the specific reasons for non-adherent behaviour.</description><identifier>ISSN: 2047-9956</identifier><identifier>EISSN: 2047-9964</identifier><identifier>DOI: 10.1136/ejhpharm-2021-002725</identifier><identifier>PMID: 34031152</identifier><language>eng</language><publisher>England: British Medical Journal Publishing Group</publisher><subject>Agreements ; Cardiology ; Cardiovascular disease ; Clinical outcomes ; Coronary Artery Disease ; coronary disease ; Coronary vessels ; Cross-Sectional Studies ; Drug dosages ; Drug stores ; Drug therapy ; Female ; Heart attacks ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors ; lipid metabolism disorders ; Male ; Medical records ; Middle Aged ; myocardial infarction ; Original Research ; Outpatient care facilities ; Patients ; Polypharmacy ; Public health ; Sociodemographics ; Statins ; Teaching hospitals ; Vein &amp; artery diseases</subject><ispartof>European journal of hospital pharmacy. Science and practice, 2023-01, Vol.30 (1), p.24-28</ispartof><rights>European Association of Hospital Pharmacists 2023. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>European Association of Hospital Pharmacists 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2023 European Association of Hospital Pharmacists 2023. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>European Association of Hospital Pharmacists 2023. No commercial re-use. See rights and permissions. Published by BMJ. 2023</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-b420t-1c3c6c700c4904ba8d576bc347b5b2c64c77db441fe6ea8b5bb0e5e63038ecb03</cites><orcidid>0000-0001-8704-4126</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811568/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811568/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34031152$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Camila de Souza Groia Veloso, Ronara</creatorcontrib><creatorcontrib>Cruzeiro, Maria Gabriela Martins</creatorcontrib><creatorcontrib>Dias, Bianca Menezes</creatorcontrib><creatorcontrib>Reis, Adriano Max Moreira</creatorcontrib><title>Assessment of adherence to statin therapy in patients with coronary artery disease: comparison of three self-reporting measures</title><title>European journal of hospital pharmacy. Science and practice</title><addtitle>Eur J Hosp Pharm</addtitle><addtitle>Eur J Hosp Pharm</addtitle><description>ObjectivesTo investigate adherence to statin therapy using three self-reporting adherence measures in patients with coronary artery disease and to compare the three measures.MethodsA cross-sectional study was carried out at a multidisciplinary outpatient clinic of cardiology at a teaching hospital in south-eastern Brazil in patients with coronary artery disease who were using statins. The sample consisted of 148 patients who were selected from April 2018 to February 2019. Adherence to statin therapy was determined by the Measure of Adherence to Treatment, Visual Analogue Scale of adherence and 7-day recall. A descriptive analysis and determination of the level of agreement between the adherence scales by the Cohen kappa coefficient were performed.ResultsThe study included 148 patients (104 (70.3%) men, median age 62 years) diagnosed with coronary artery disease who were using statins. The adherence to statin therapy was 98.6% using the Measure of Adherence to Treatment, 95.9% with the Visual Analogue Scale and 95.3% with 7-day recall. Agreement between the Measure of Adherence to Treatment and the Visual Analogue Scale (0.277) and the Measure of Adherence to Treatment and 7-day recall (0.241) was low. There was a high level of agreement between the Visual Analogue Scale and 7-day recall (0.759).ConclusionsThe adherence Visual Analogue Scale and 7-day recall were shown to be easy to apply, low-cost adherence measures to identify adherence to statins in patients with coronary artery disease. 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Cruzeiro, Maria Gabriela Martins ; Dias, Bianca Menezes ; Reis, Adriano Max Moreira</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b420t-1c3c6c700c4904ba8d576bc347b5b2c64c77db441fe6ea8b5bb0e5e63038ecb03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Agreements</topic><topic>Cardiology</topic><topic>Cardiovascular disease</topic><topic>Clinical outcomes</topic><topic>Coronary Artery Disease</topic><topic>coronary disease</topic><topic>Coronary vessels</topic><topic>Cross-Sectional Studies</topic><topic>Drug dosages</topic><topic>Drug stores</topic><topic>Drug therapy</topic><topic>Female</topic><topic>Heart attacks</topic><topic>Humans</topic><topic>Hydroxymethylglutaryl-CoA Reductase Inhibitors</topic><topic>lipid metabolism disorders</topic><topic>Male</topic><topic>Medical records</topic><topic>Middle Aged</topic><topic>myocardial infarction</topic><topic>Original Research</topic><topic>Outpatient care facilities</topic><topic>Patients</topic><topic>Polypharmacy</topic><topic>Public health</topic><topic>Sociodemographics</topic><topic>Statins</topic><topic>Teaching hospitals</topic><topic>Vein &amp; 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Science and practice</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Camila de Souza Groia Veloso, Ronara</au><au>Cruzeiro, Maria Gabriela Martins</au><au>Dias, Bianca Menezes</au><au>Reis, Adriano Max Moreira</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of adherence to statin therapy in patients with coronary artery disease: comparison of three self-reporting measures</atitle><jtitle>European journal of hospital pharmacy. Science and practice</jtitle><stitle>Eur J Hosp Pharm</stitle><addtitle>Eur J Hosp Pharm</addtitle><date>2023-01-01</date><risdate>2023</risdate><volume>30</volume><issue>1</issue><spage>24</spage><epage>28</epage><pages>24-28</pages><issn>2047-9956</issn><eissn>2047-9964</eissn><abstract>ObjectivesTo investigate adherence to statin therapy using three self-reporting adherence measures in patients with coronary artery disease and to compare the three measures.MethodsA cross-sectional study was carried out at a multidisciplinary outpatient clinic of cardiology at a teaching hospital in south-eastern Brazil in patients with coronary artery disease who were using statins. The sample consisted of 148 patients who were selected from April 2018 to February 2019. Adherence to statin therapy was determined by the Measure of Adherence to Treatment, Visual Analogue Scale of adherence and 7-day recall. A descriptive analysis and determination of the level of agreement between the adherence scales by the Cohen kappa coefficient were performed.ResultsThe study included 148 patients (104 (70.3%) men, median age 62 years) diagnosed with coronary artery disease who were using statins. The adherence to statin therapy was 98.6% using the Measure of Adherence to Treatment, 95.9% with the Visual Analogue Scale and 95.3% with 7-day recall. Agreement between the Measure of Adherence to Treatment and the Visual Analogue Scale (0.277) and the Measure of Adherence to Treatment and 7-day recall (0.241) was low. There was a high level of agreement between the Visual Analogue Scale and 7-day recall (0.759).ConclusionsThe adherence Visual Analogue Scale and 7-day recall were shown to be easy to apply, low-cost adherence measures to identify adherence to statins in patients with coronary artery disease. The Measure of Adherence to Treatment may also be used to provide information regarding the specific reasons for non-adherent behaviour.</abstract><cop>England</cop><pub>British Medical Journal Publishing Group</pub><pmid>34031152</pmid><doi>10.1136/ejhpharm-2021-002725</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0001-8704-4126</orcidid></addata></record>
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subjects Agreements
Cardiology
Cardiovascular disease
Clinical outcomes
Coronary Artery Disease
coronary disease
Coronary vessels
Cross-Sectional Studies
Drug dosages
Drug stores
Drug therapy
Female
Heart attacks
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
lipid metabolism disorders
Male
Medical records
Middle Aged
myocardial infarction
Original Research
Outpatient care facilities
Patients
Polypharmacy
Public health
Sociodemographics
Statins
Teaching hospitals
Vein & artery diseases
title Assessment of adherence to statin therapy in patients with coronary artery disease: comparison of three self-reporting measures
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