Extreme In Situ Liver Surgery Under Total Vascular Exclusion with Right Hepatic Vein and Inferior Vena Cava Grafts for an Intrahepatic Cholangiocarcinoma
In this multimedia article, we demonstrate an extreme in situ liver surgery under total vascular exclusion with right hepatic vein and inferior vena cava grafts for an intrahepatic cholangiocarcinoma in a centre with experience in highly complex hepatobiliary surgery and liver transplantation. This...
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Veröffentlicht in: | Annals of surgical oncology 2023-02, Vol.30 (2), p.764-765 |
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creator | Lopez-Lopez, Victor Valles, Paula Gomez Palenciano, Carlos García Canovas, Sergio Conesa, Asunción López Brusadin, Roberto Robles-Campos, Ricardo |
description | In this multimedia article, we demonstrate an extreme in situ liver surgery under total vascular exclusion with right hepatic vein and inferior vena cava grafts for an intrahepatic cholangiocarcinoma in a centre with experience in highly complex hepatobiliary surgery and liver transplantation. This surgical approach after neoadjuvant chemotherapy provides an opportunity for surgical salvage in patients with large tumors invading the hepatocaval confluence. This patient was considered unresectable at another hospital and referred to our unit. We performed an accurate preoperative assessment with new generation 3D modelling to plan the type of vascular reconstruction that would allow adequate hepatic venous outflow and the volume of the future liver remnant sufficient to avoid postoperative liver failure. For hemodynamic management of the patient, we performed a total hepatic vascular exclusion with veno-venous bypass without intraoperative adverse events. We used a cryopreserved carotid artery graft after previously planning the most appropriate diameter and length for right hepatic vein reconstruction. The inferior vena cava was reconstructed with gore-tex graft. During the hospital stay there were no postoperative complications. The patient is free of disease. We conclude that patients with advanced malignant liver disease should always be referred to highly specialized liver surgery centers to assess the most appropriate oncological management and the possibility of surgical resectability. |
doi_str_mv | 10.1245/s10434-022-12787-4 |
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This surgical approach after neoadjuvant chemotherapy provides an opportunity for surgical salvage in patients with large tumors invading the hepatocaval confluence. This patient was considered unresectable at another hospital and referred to our unit. We performed an accurate preoperative assessment with new generation 3D modelling to plan the type of vascular reconstruction that would allow adequate hepatic venous outflow and the volume of the future liver remnant sufficient to avoid postoperative liver failure. For hemodynamic management of the patient, we performed a total hepatic vascular exclusion with veno-venous bypass without intraoperative adverse events. We used a cryopreserved carotid artery graft after previously planning the most appropriate diameter and length for right hepatic vein reconstruction. The inferior vena cava was reconstructed with gore-tex graft. During the hospital stay there were no postoperative complications. The patient is free of disease. We conclude that patients with advanced malignant liver disease should always be referred to highly specialized liver surgery centers to assess the most appropriate oncological management and the possibility of surgical resectability.</description><identifier>ISSN: 1068-9265</identifier><identifier>EISSN: 1534-4681</identifier><identifier>DOI: 10.1245/s10434-022-12787-4</identifier><identifier>PMID: 36463359</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Bile Duct Neoplasms - pathology ; Bile Duct Neoplasms - surgery ; Bile Ducts, Intrahepatic - pathology ; Bile Ducts, Intrahepatic - surgery ; Blood flow ; Carotid artery ; Chemotherapy ; Cholangiocarcinoma ; Cholangiocarcinoma - pathology ; Cholangiocarcinoma - surgery ; Complications ; Cryopreservation ; Hepatectomy ; Hepatic vein ; Hepatic Veins - pathology ; Hepatic Veins - surgery ; Hepatobiliary Tumors ; Humans ; Liver ; Liver diseases ; Liver Neoplasms - pathology ; Liver Neoplasms - surgery ; Liver transplantation ; Medicine ; Medicine & Public Health ; Oncology ; Patients ; Postoperative ; Reconstructive surgery ; Surgery ; Surgical Oncology ; Tumors ; Veins & arteries ; Vena Cava, Inferior - pathology ; Vena Cava, Inferior - surgery</subject><ispartof>Annals of surgical oncology, 2023-02, Vol.30 (2), p.764-765</ispartof><rights>The Author(s) 2022</rights><rights>2022. The Author(s).</rights><rights>The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). 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This surgical approach after neoadjuvant chemotherapy provides an opportunity for surgical salvage in patients with large tumors invading the hepatocaval confluence. This patient was considered unresectable at another hospital and referred to our unit. We performed an accurate preoperative assessment with new generation 3D modelling to plan the type of vascular reconstruction that would allow adequate hepatic venous outflow and the volume of the future liver remnant sufficient to avoid postoperative liver failure. For hemodynamic management of the patient, we performed a total hepatic vascular exclusion with veno-venous bypass without intraoperative adverse events. We used a cryopreserved carotid artery graft after previously planning the most appropriate diameter and length for right hepatic vein reconstruction. The inferior vena cava was reconstructed with gore-tex graft. During the hospital stay there were no postoperative complications. The patient is free of disease. 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This surgical approach after neoadjuvant chemotherapy provides an opportunity for surgical salvage in patients with large tumors invading the hepatocaval confluence. This patient was considered unresectable at another hospital and referred to our unit. We performed an accurate preoperative assessment with new generation 3D modelling to plan the type of vascular reconstruction that would allow adequate hepatic venous outflow and the volume of the future liver remnant sufficient to avoid postoperative liver failure. For hemodynamic management of the patient, we performed a total hepatic vascular exclusion with veno-venous bypass without intraoperative adverse events. We used a cryopreserved carotid artery graft after previously planning the most appropriate diameter and length for right hepatic vein reconstruction. The inferior vena cava was reconstructed with gore-tex graft. During the hospital stay there were no postoperative complications. The patient is free of disease. 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subjects | Bile Duct Neoplasms - pathology Bile Duct Neoplasms - surgery Bile Ducts, Intrahepatic - pathology Bile Ducts, Intrahepatic - surgery Blood flow Carotid artery Chemotherapy Cholangiocarcinoma Cholangiocarcinoma - pathology Cholangiocarcinoma - surgery Complications Cryopreservation Hepatectomy Hepatic vein Hepatic Veins - pathology Hepatic Veins - surgery Hepatobiliary Tumors Humans Liver Liver diseases Liver Neoplasms - pathology Liver Neoplasms - surgery Liver transplantation Medicine Medicine & Public Health Oncology Patients Postoperative Reconstructive surgery Surgery Surgical Oncology Tumors Veins & arteries Vena Cava, Inferior - pathology Vena Cava, Inferior - surgery |
title | Extreme In Situ Liver Surgery Under Total Vascular Exclusion with Right Hepatic Vein and Inferior Vena Cava Grafts for an Intrahepatic Cholangiocarcinoma |
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