Extracellular proteins OSM-7 and OSM-8 are required for stress response gene regulation at all post-embryonic stages

Extracellular matrices (ECMs) act as barriers to environmental stress on the outer surface of animals. Within cells, well-studied molecular pathways sense stress and regulate cytoprotective gene expression (Choe et al. 2009, Blackwell et al. 2015, Urso and Lamitina 2021, Pujol and Ewbank 2022). Desp...

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Veröffentlicht in:microPublication biology 2022, Vol.2022
Hauptverfasser: Rodriguez Mendoza, Victoria, Chandler, Luke, Liu, Zhexin, Buddendorff, Lauren, Al-Rajhi, Amal, Choi, Thine, Gibb, Gabrielle, Harvey, Justin, Mihalik, Alva, Moravec, Sophie, Pilcher, Wendy, Raju, Vikram, Choe, Keith Patrick
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container_title microPublication biology
container_volume 2022
creator Rodriguez Mendoza, Victoria
Chandler, Luke
Liu, Zhexin
Buddendorff, Lauren
Al-Rajhi, Amal
Choi, Thine
Gibb, Gabrielle
Harvey, Justin
Mihalik, Alva
Moravec, Sophie
Pilcher, Wendy
Raju, Vikram
Choe, Keith Patrick
description Extracellular matrices (ECMs) act as barriers to environmental stress on the outer surface of animals. Within cells, well-studied molecular pathways sense stress and regulate cytoprotective gene expression (Choe et al. 2009, Blackwell et al. 2015, Urso and Lamitina 2021, Pujol and Ewbank 2022). Despite being in direct contact with the environment, little is known about the role of barrier ECMs in sensing environmental conditions and regulating stress response genes in underlying cells.
doi_str_mv 10.17912/micropub.biology.000688
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subjects C. Elegans
Expression Data
New Finding
Phenotype Data
title Extracellular proteins OSM-7 and OSM-8 are required for stress response gene regulation at all post-embryonic stages
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