AGAP3: A novel BRAF fusion partner in pediatric pancreatic‐type acinar cell carcinoma

Most available molecular data on pancreatic acinar cell carcinoma (PACC) are provided by studies of adult cases. BRAF, RAF1, or RET rearrangements have been described in approximately 30% of cases. To the best of our knowledge, only seven cases with molecular data have been reported in pediatric PAC...

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Veröffentlicht in:	Genes chromosomes & cancer 2022-12, Vol.61 (12), p.734-739
Hauptverfasser:	Paoli, Charlotte, Burel‐Vandenbos, Fanny, Coulomb‐l'Hermine, Aurore, Cros, Jérôme, Pondrom, Morgane, Kubiniek, Valérie, Pedeutour, Florence, Dadone‐Montaudié, Bérengère
Format:	Artikel
Sprache:	eng
Schlagworte:	acinar cell carcinoma Adult BRAF rearrangement Brief Report Brief Reports Carcinoma, Acinar Cell - genetics Carcinoma, Acinar Cell - pathology Child Chromosome 7 fusion gene Genomic instability Glutamic acid receptors (ionotropic) Humans MEK inhibitors Metastases Mitogen-Activated Protein Kinase Kinases - genetics Mutation N-Methyl-D-aspartic acid receptors N-Methylaspartate - genetics Pancreas Pancreatic cancer Pancreatic carcinoma Pancreatic Neoplasms Pancreatic Neoplasms - genetics Pancreatic Neoplasms - pathology pediatric Pediatrics Proto-Oncogene Proteins B-raf - genetics RNA sequencing
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