Growth Differentiation Factor 7 Prevents Sepsis-Induced Acute Lung Injury in Mice

Objective. Acute lung injury (ALI) is a life-threatening complication during sepsis and contributes to multiple organ failure and high mortality for septic patients. The present study aims to investigate the role and molecular basis of growth differentiation factor 7 (GDF7) in sepsis-induced ALI. Me...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2022, Vol.2022, p.3676444-13
Hauptverfasser:	Dong, Ping, Zhang, Ying, Liu, Nian, Yang, Jun-Yuan, Wang, Hui-Min, Geng, Qing
Format:	Artikel
Sprache:	eng
Schlagworte:	AMP-activated protein kinase Cytokines Dehydrogenases Inflammation Kinases Laboratory animals Lipid peroxidation Lipopolysaccharides Lungs Macrophages Oxidative stress Proteins Reagents Rodents Sepsis Tumor necrosis factor-TNF
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