Antimicrobial Efficacy of Silver Diamine Fluoride against Enterococcus faecalis: A Systematic Review of In Vitro Studies
Introduction/Objectives. Enterococcus faecalis has been implicated in infections of treated root canals. Current irrigants and intracanal medicaments cannot eliminate E. faecalis completely from the root canal. Silver diamine fluoride (SDF) prevents caries by promoting remineralization and exerting...
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description | Introduction/Objectives. Enterococcus faecalis has been implicated in infections of treated root canals. Current irrigants and intracanal medicaments cannot eliminate E. faecalis completely from the root canal. Silver diamine fluoride (SDF) prevents caries by promoting remineralization and exerting an antibacterial effect. Studies suggest that SDF may possess antibacterial properties against E. faecalis. The purpose of this review is to systematically and critically analyze the literature, focusing on the use of SDF as an intracanal medicament or irrigant, when compared to other antibacterial agents. Data/Sources. The focused question was “Is the antibacterial effect of SDF against E. faecalis better than other intracanal medicaments and irrigants?” Using the keywords ((silver diamine fluoride) AND (Enterococcus faecalis)) AND ((sodium hypochlorite) OR (NaOCl) OR (chlorhexidine) OR (calcium hydroxide) OR (Ca(OH)2)), an electronic search was conducted on the following databases: PubMed/MEDLINE, ISI Web of Science, Scopus, EMBASE, and Google Scholar. The clinical trial registers ClinicalTrials.gov and CONTROL were also searched using the same keywords. General characteristics and outcomes were extracted, and quality of the studies was assessed using the Preferred Reporting Items for Laboratory studies in Endodontology (PRILE) guidelines. Study Selection. Six articles (five in vitro studies and one ex vivo study) were included in this systematic review. In the majority of the studies, SDF had equal or better antibacterial efficacy against E. faecalis compared to calcium hydroxide, sodium hypochlorite, and chlorhexidine. However, the majority of the studies did not fulfill several items in the PRILE criteria and had numerous sources of bias. Conclusions. Within the limitations of the systematic review and the studies reviewed, SDF may be effective against E. faecalis and therefore could be used as an intracanal medicament and/or irrigant to prevent reinfections of the root canals and improve the outcomes of endodontic treatment. However, animal and clinical studies should be carried out to determine the efficacy of SDF in endodontics. Trial Registration. The protocol for this review was registered on PROSPERO. Registration number: CRD42021224741. |
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Enterococcus faecalis has been implicated in infections of treated root canals. Current irrigants and intracanal medicaments cannot eliminate E. faecalis completely from the root canal. Silver diamine fluoride (SDF) prevents caries by promoting remineralization and exerting an antibacterial effect. Studies suggest that SDF may possess antibacterial properties against E. faecalis. The purpose of this review is to systematically and critically analyze the literature, focusing on the use of SDF as an intracanal medicament or irrigant, when compared to other antibacterial agents. Data/Sources. The focused question was “Is the antibacterial effect of SDF against E. faecalis better than other intracanal medicaments and irrigants?” Using the keywords ((silver diamine fluoride) AND (Enterococcus faecalis)) AND ((sodium hypochlorite) OR (NaOCl) OR (chlorhexidine) OR (calcium hydroxide) OR (Ca(OH)2)), an electronic search was conducted on the following databases: PubMed/MEDLINE, ISI Web of Science, Scopus, EMBASE, and Google Scholar. The clinical trial registers ClinicalTrials.gov and CONTROL were also searched using the same keywords. General characteristics and outcomes were extracted, and quality of the studies was assessed using the Preferred Reporting Items for Laboratory studies in Endodontology (PRILE) guidelines. Study Selection. Six articles (five in vitro studies and one ex vivo study) were included in this systematic review. In the majority of the studies, SDF had equal or better antibacterial efficacy against E. faecalis compared to calcium hydroxide, sodium hypochlorite, and chlorhexidine. However, the majority of the studies did not fulfill several items in the PRILE criteria and had numerous sources of bias. Conclusions. Within the limitations of the systematic review and the studies reviewed, SDF may be effective against E. faecalis and therefore could be used as an intracanal medicament and/or irrigant to prevent reinfections of the root canals and improve the outcomes of endodontic treatment. However, animal and clinical studies should be carried out to determine the efficacy of SDF in endodontics. Trial Registration. The protocol for this review was registered on PROSPERO. Registration number: CRD42021224741.</description><identifier>ISSN: 2314-6133</identifier><identifier>ISSN: 2314-6141</identifier><identifier>EISSN: 2314-6141</identifier><identifier>DOI: 10.1155/2022/6544292</identifier><identifier>PMID: 36567909</identifier><language>eng</language><publisher>United States: Hindawi</publisher><subject>Animals ; Anti-Bacterial Agents - pharmacology ; Anti-Bacterial Agents - therapeutic use ; Anti-infective agents ; Anti-Infective Agents - pharmacology ; Antibacterial activity ; Antibacterial agents ; Calcium hydroxide ; Calcium Hydroxide - pharmacology ; Calcium hypochlorite ; Chlorhexidine ; Chlorhexidine - pharmacology ; Complications and side effects ; Dental caries ; Dental Pulp Cavity ; Diamines ; Effectiveness ; Endodontics ; Enterococcal infections ; Enterococcus faecalis ; Fluoride treatment ; Fluoride treatments ; Fluorides ; Keywords ; Laboratories ; Prevention ; Remineralization ; Review ; Reviews ; Risk factors ; Root canal therapy ; Root canals ; Silver ; Slaked lime ; Sodium ; Sodium Hypochlorite ; Systematic review</subject><ispartof>BioMed research international, 2022, Vol.2022 (1), p.6544292</ispartof><rights>Copyright © 2022 Juzer Shabbir et al.</rights><rights>COPYRIGHT 2022 John Wiley & Sons, Inc.</rights><rights>Copyright © 2022 Juzer Shabbir et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2022 Juzer Shabbir et al. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c476t-114b936a45987f6934bfd203512e86dee49ed0f91cada8403e3285cbf6473df03</citedby><cites>FETCH-LOGICAL-c476t-114b936a45987f6934bfd203512e86dee49ed0f91cada8403e3285cbf6473df03</cites><orcidid>0000-0003-0149-5431 ; 0000-0003-1209-9362 ; 0000-0002-3803-6055 ; 0000-0002-8773-8029 ; 0000-0001-7998-7335 ; 0000-0002-5157-7067 ; 0000-0002-4968-6221</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788898/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788898/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,4010,27904,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36567909$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>J, Heng Bo</contributor><contributor>Heng Bo J</contributor><creatorcontrib>Shabbir, Juzer</creatorcontrib><creatorcontrib>Khurshid, Zohaib</creatorcontrib><creatorcontrib>Zafar, Muhammad Sohail</creatorcontrib><creatorcontrib>Farooqui, Waqas Ahmed</creatorcontrib><creatorcontrib>Imran, Eisha</creatorcontrib><creatorcontrib>Najeeb, Shariq</creatorcontrib><creatorcontrib>Bencharit, Sompop</creatorcontrib><title>Antimicrobial Efficacy of Silver Diamine Fluoride against Enterococcus faecalis: A Systematic Review of In Vitro Studies</title><title>BioMed research international</title><addtitle>Biomed Res Int</addtitle><description>Introduction/Objectives. Enterococcus faecalis has been implicated in infections of treated root canals. Current irrigants and intracanal medicaments cannot eliminate E. faecalis completely from the root canal. Silver diamine fluoride (SDF) prevents caries by promoting remineralization and exerting an antibacterial effect. Studies suggest that SDF may possess antibacterial properties against E. faecalis. The purpose of this review is to systematically and critically analyze the literature, focusing on the use of SDF as an intracanal medicament or irrigant, when compared to other antibacterial agents. Data/Sources. The focused question was “Is the antibacterial effect of SDF against E. faecalis better than other intracanal medicaments and irrigants?” Using the keywords ((silver diamine fluoride) AND (Enterococcus faecalis)) AND ((sodium hypochlorite) OR (NaOCl) OR (chlorhexidine) OR (calcium hydroxide) OR (Ca(OH)2)), an electronic search was conducted on the following databases: PubMed/MEDLINE, ISI Web of Science, Scopus, EMBASE, and Google Scholar. The clinical trial registers ClinicalTrials.gov and CONTROL were also searched using the same keywords. General characteristics and outcomes were extracted, and quality of the studies was assessed using the Preferred Reporting Items for Laboratory studies in Endodontology (PRILE) guidelines. Study Selection. Six articles (five in vitro studies and one ex vivo study) were included in this systematic review. In the majority of the studies, SDF had equal or better antibacterial efficacy against E. faecalis compared to calcium hydroxide, sodium hypochlorite, and chlorhexidine. However, the majority of the studies did not fulfill several items in the PRILE criteria and had numerous sources of bias. Conclusions. Within the limitations of the systematic review and the studies reviewed, SDF may be effective against E. faecalis and therefore could be used as an intracanal medicament and/or irrigant to prevent reinfections of the root canals and improve the outcomes of endodontic treatment. However, animal and clinical studies should be carried out to determine the efficacy of SDF in endodontics. Trial Registration. The protocol for this review was registered on PROSPERO. Registration number: CRD42021224741.</description><subject>Animals</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Anti-infective agents</subject><subject>Anti-Infective Agents - pharmacology</subject><subject>Antibacterial activity</subject><subject>Antibacterial agents</subject><subject>Calcium hydroxide</subject><subject>Calcium Hydroxide - pharmacology</subject><subject>Calcium hypochlorite</subject><subject>Chlorhexidine</subject><subject>Chlorhexidine - pharmacology</subject><subject>Complications and side effects</subject><subject>Dental caries</subject><subject>Dental Pulp Cavity</subject><subject>Diamines</subject><subject>Effectiveness</subject><subject>Endodontics</subject><subject>Enterococcal infections</subject><subject>Enterococcus faecalis</subject><subject>Fluoride treatment</subject><subject>Fluoride treatments</subject><subject>Fluorides</subject><subject>Keywords</subject><subject>Laboratories</subject><subject>Prevention</subject><subject>Remineralization</subject><subject>Review</subject><subject>Reviews</subject><subject>Risk factors</subject><subject>Root canal therapy</subject><subject>Root canals</subject><subject>Silver</subject><subject>Slaked lime</subject><subject>Sodium</subject><subject>Sodium Hypochlorite</subject><subject>Systematic review</subject><issn>2314-6133</issn><issn>2314-6141</issn><issn>2314-6141</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kU1vEzEQhlcIRKvSG2dkiQsShPp71xyQopJCpUpIBLhajnecTrVrF3u3Jf-eDQnh44AvtjSPHs_MW1VPGX3NmFJnnHJ-ppWU3PAH1TEXTM40k-zh4S3EUXVayg2dTsM0NfpxdSS00rWh5rj6Po8D9uhzWqHryCIE9M5vSApkid0dZPIOXY8RyEU3powtELd2GMtAFnGAnHzyfiwkOPCuw_KGzMlyUwbo3YCefII7hPut7TKSrzjkRJbD2CKUJ9Wj4LoCp_v7pPpysfh8_mF29fH95fn8auZlrYcZY3JlhHZSmaYO2gi5Ci2nQjEOjW4BpIGWBsO8a10jqQDBG-VXQctatIGKk-rtzns7rnpoPcQhu87eZuxd3tjk0P5diXht1-nOmrppGtNMghd7QU7fRiiD7bF46DoXIY3F8lo1Qqla1xP6_B_0Jo05TuP9pCjX095_U2vXgcUY0vSv30rtvBaMca6VmahXO2qKppQM4dAyo3abvd1mb_fZT_izP8c8wL-SnoCXO-AaY-vu8f-6H98eteQ</recordid><startdate>2022</startdate><enddate>2022</enddate><creator>Shabbir, Juzer</creator><creator>Khurshid, Zohaib</creator><creator>Zafar, Muhammad Sohail</creator><creator>Farooqui, Waqas Ahmed</creator><creator>Imran, Eisha</creator><creator>Najeeb, Shariq</creator><creator>Bencharit, Sompop</creator><general>Hindawi</general><general>John Wiley & Sons, Inc</general><general>Hindawi Limited</general><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7QO</scope><scope>7T7</scope><scope>7TK</scope><scope>7U7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>CWDGH</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-0149-5431</orcidid><orcidid>https://orcid.org/0000-0003-1209-9362</orcidid><orcidid>https://orcid.org/0000-0002-3803-6055</orcidid><orcidid>https://orcid.org/0000-0002-8773-8029</orcidid><orcidid>https://orcid.org/0000-0001-7998-7335</orcidid><orcidid>https://orcid.org/0000-0002-5157-7067</orcidid><orcidid>https://orcid.org/0000-0002-4968-6221</orcidid></search><sort><creationdate>2022</creationdate><title>Antimicrobial Efficacy of Silver Diamine Fluoride against Enterococcus faecalis: A Systematic Review of In Vitro Studies</title><author>Shabbir, Juzer ; Khurshid, Zohaib ; Zafar, Muhammad Sohail ; Farooqui, Waqas Ahmed ; Imran, Eisha ; Najeeb, Shariq ; Bencharit, Sompop</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c476t-114b936a45987f6934bfd203512e86dee49ed0f91cada8403e3285cbf6473df03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Animals</topic><topic>Anti-Bacterial Agents - pharmacology</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Anti-infective agents</topic><topic>Anti-Infective Agents - pharmacology</topic><topic>Antibacterial activity</topic><topic>Antibacterial agents</topic><topic>Calcium hydroxide</topic><topic>Calcium Hydroxide - pharmacology</topic><topic>Calcium hypochlorite</topic><topic>Chlorhexidine</topic><topic>Chlorhexidine - pharmacology</topic><topic>Complications and side effects</topic><topic>Dental caries</topic><topic>Dental Pulp Cavity</topic><topic>Diamines</topic><topic>Effectiveness</topic><topic>Endodontics</topic><topic>Enterococcal infections</topic><topic>Enterococcus faecalis</topic><topic>Fluoride treatment</topic><topic>Fluoride treatments</topic><topic>Fluorides</topic><topic>Keywords</topic><topic>Laboratories</topic><topic>Prevention</topic><topic>Remineralization</topic><topic>Review</topic><topic>Reviews</topic><topic>Risk factors</topic><topic>Root canal therapy</topic><topic>Root canals</topic><topic>Silver</topic><topic>Slaked lime</topic><topic>Sodium</topic><topic>Sodium Hypochlorite</topic><topic>Systematic review</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shabbir, Juzer</creatorcontrib><creatorcontrib>Khurshid, Zohaib</creatorcontrib><creatorcontrib>Zafar, Muhammad Sohail</creatorcontrib><creatorcontrib>Farooqui, Waqas Ahmed</creatorcontrib><creatorcontrib>Imran, Eisha</creatorcontrib><creatorcontrib>Najeeb, Shariq</creatorcontrib><creatorcontrib>Bencharit, Sompop</creatorcontrib><collection>Hindawi Publishing Complete</collection><collection>Hindawi Publishing Subscription Journals</collection><collection>Hindawi Publishing Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Middle East & Africa Database</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BioMed research international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shabbir, Juzer</au><au>Khurshid, Zohaib</au><au>Zafar, Muhammad Sohail</au><au>Farooqui, Waqas Ahmed</au><au>Imran, Eisha</au><au>Najeeb, Shariq</au><au>Bencharit, Sompop</au><au>J, Heng Bo</au><au>Heng Bo J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antimicrobial Efficacy of Silver Diamine Fluoride against Enterococcus faecalis: A Systematic Review of In Vitro Studies</atitle><jtitle>BioMed research international</jtitle><addtitle>Biomed Res Int</addtitle><date>2022</date><risdate>2022</risdate><volume>2022</volume><issue>1</issue><spage>6544292</spage><pages>6544292-</pages><issn>2314-6133</issn><issn>2314-6141</issn><eissn>2314-6141</eissn><abstract>Introduction/Objectives. Enterococcus faecalis has been implicated in infections of treated root canals. Current irrigants and intracanal medicaments cannot eliminate E. faecalis completely from the root canal. Silver diamine fluoride (SDF) prevents caries by promoting remineralization and exerting an antibacterial effect. Studies suggest that SDF may possess antibacterial properties against E. faecalis. The purpose of this review is to systematically and critically analyze the literature, focusing on the use of SDF as an intracanal medicament or irrigant, when compared to other antibacterial agents. Data/Sources. The focused question was “Is the antibacterial effect of SDF against E. faecalis better than other intracanal medicaments and irrigants?” Using the keywords ((silver diamine fluoride) AND (Enterococcus faecalis)) AND ((sodium hypochlorite) OR (NaOCl) OR (chlorhexidine) OR (calcium hydroxide) OR (Ca(OH)2)), an electronic search was conducted on the following databases: PubMed/MEDLINE, ISI Web of Science, Scopus, EMBASE, and Google Scholar. The clinical trial registers ClinicalTrials.gov and CONTROL were also searched using the same keywords. General characteristics and outcomes were extracted, and quality of the studies was assessed using the Preferred Reporting Items for Laboratory studies in Endodontology (PRILE) guidelines. Study Selection. Six articles (five in vitro studies and one ex vivo study) were included in this systematic review. In the majority of the studies, SDF had equal or better antibacterial efficacy against E. faecalis compared to calcium hydroxide, sodium hypochlorite, and chlorhexidine. However, the majority of the studies did not fulfill several items in the PRILE criteria and had numerous sources of bias. Conclusions. Within the limitations of the systematic review and the studies reviewed, SDF may be effective against E. faecalis and therefore could be used as an intracanal medicament and/or irrigant to prevent reinfections of the root canals and improve the outcomes of endodontic treatment. However, animal and clinical studies should be carried out to determine the efficacy of SDF in endodontics. Trial Registration. The protocol for this review was registered on PROSPERO. Registration number: CRD42021224741.</abstract><cop>United States</cop><pub>Hindawi</pub><pmid>36567909</pmid><doi>10.1155/2022/6544292</doi><orcidid>https://orcid.org/0000-0003-0149-5431</orcidid><orcidid>https://orcid.org/0000-0003-1209-9362</orcidid><orcidid>https://orcid.org/0000-0002-3803-6055</orcidid><orcidid>https://orcid.org/0000-0002-8773-8029</orcidid><orcidid>https://orcid.org/0000-0001-7998-7335</orcidid><orcidid>https://orcid.org/0000-0002-5157-7067</orcidid><orcidid>https://orcid.org/0000-0002-4968-6221</orcidid><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; PubMed Central Open Access; Wiley-Blackwell Open Access Titles; PubMed Central; Alma/SFX Local Collection |
subjects | Animals Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Anti-infective agents Anti-Infective Agents - pharmacology Antibacterial activity Antibacterial agents Calcium hydroxide Calcium Hydroxide - pharmacology Calcium hypochlorite Chlorhexidine Chlorhexidine - pharmacology Complications and side effects Dental caries Dental Pulp Cavity Diamines Effectiveness Endodontics Enterococcal infections Enterococcus faecalis Fluoride treatment Fluoride treatments Fluorides Keywords Laboratories Prevention Remineralization Review Reviews Risk factors Root canal therapy Root canals Silver Slaked lime Sodium Sodium Hypochlorite Systematic review |
title | Antimicrobial Efficacy of Silver Diamine Fluoride against Enterococcus faecalis: A Systematic Review of In Vitro Studies |
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