Flavanol Consumption in Healthy Men Preserves Integrity of Immunological‐Endothelial Barrier Cell Functions: Nutri(epi)genomic Analysis

Scope While cocoa flavanol (CF) consumption improves cardiovascular risk biomarkers, molecular mechanisms underlying their protective effects are not understood. Objective To investigate nutri(epi)genomic effects of CF and identify regulatory networks potential mediating vascular health benefits. Me...

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Veröffentlicht in:	Molecular nutrition & food research 2022-11, Vol.66 (21), p.e2100991-n/a
Hauptverfasser:	Milenkovic, Dragan, Rodriguez‐Mateos, Ana, Lucosz, Margarete, Istas, Geoffrey, Declerck, Ken, Sansone, Roberto, Deenen, René, Köhrer, Karl, Corral‐Jara, Karla Fabiola, Altschmied, Joachim, Haendeler, Judith, Kelm, Malte, Berghe, Wim Vanden, Heiss, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Adhesion Angiogenesis Biomarkers Blood Pressure Cacao - chemistry Cardiovascular diseases Cell adhesion Cell adhesion & migration Cell signaling Chemotaxis clinical trial Cocoa cocoa flavanol Consumption Cytoskeleton Deoxyribonucleic acid DNA DNA methylation DNA microarrays Double-Blind Method epicatechin Flavanols Flavonols - pharmacology Food and Nutrition Gene expression Genes Genomic analysis Genomics Health risks Humans Immune response Immune system Immunology Integrity Life Sciences Male Metabolites Middle Aged Molecular modelling Monocytes Nitric oxide Polyphenols - pharmacology Signaling Stiffness Transcription factors
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