A Predictive Model for Dysphagia after Ventilator Liberation in Severe Pneumonia Patients Receiving Tracheostomy: A Single-Center, Observational Study
The main purpose of this study was to develop a model predictive of dysphagia in hospital survivors with severe pneumonia who underwent tracheostomy during their hospital stay. The present study included 175 patients (72% male; mean age, 71.3 years) over 5 years. None of these patients had a history...
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Veröffentlicht in: | Journal of clinical medicine 2022-12, Vol.11 (24), p.7391 |
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description | The main purpose of this study was to develop a model predictive of dysphagia in hospital survivors with severe pneumonia who underwent tracheostomy during their hospital stay. The present study included 175 patients (72% male; mean age, 71.3 years) over 5 years. None of these patients had a history of deglutition disorder before hospital admission. Binary logistic regression analysis was performed to identify factors predicting dysphagia at hospital discharge. Dysphagia scores were calculated from β-coefficients and by assigning points to variables. Of the enrolled patients, 105 (60%) had dysphagia at hospital discharge. Factors prognostic of dysphagia at hospital discharge included being underweight (body mass index < 18.5 kg/m2), non-participation in a dysphagia therapy program, mechanical ventilation ≥ 15 days, age ≥ 74 years, and chronic neurologic diseases. Underweight and non-participation in a dysphagia therapy program were assigned +2 points and the other factors were assigned +1 point. Dysphagia scores showed acceptable discrimination (area under the receiver operating characteristic curve for dysphagia 0.819, 95% confidence interval: 0.754−0.873, p < 0.001) and calibration (Hosmer−Lemeshow chi-square = 9.585, with df 7 and p = 0.213). The developed dysphagia score was predictive of deglutition disorder at hospital discharge in tracheostomized patients with severe pneumonia. |
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The present study included 175 patients (72% male; mean age, 71.3 years) over 5 years. None of these patients had a history of deglutition disorder before hospital admission. Binary logistic regression analysis was performed to identify factors predicting dysphagia at hospital discharge. Dysphagia scores were calculated from β-coefficients and by assigning points to variables. Of the enrolled patients, 105 (60%) had dysphagia at hospital discharge. Factors prognostic of dysphagia at hospital discharge included being underweight (body mass index < 18.5 kg/m2), non-participation in a dysphagia therapy program, mechanical ventilation ≥ 15 days, age ≥ 74 years, and chronic neurologic diseases. Underweight and non-participation in a dysphagia therapy program were assigned +2 points and the other factors were assigned +1 point. Dysphagia scores showed acceptable discrimination (area under the receiver operating characteristic curve for dysphagia 0.819, 95% confidence interval: 0.754−0.873, p < 0.001) and calibration (Hosmer−Lemeshow chi-square = 9.585, with df 7 and p = 0.213). The developed dysphagia score was predictive of deglutition disorder at hospital discharge in tracheostomized patients with severe pneumonia.</description><identifier>ISSN: 2077-0383</identifier><identifier>EISSN: 2077-0383</identifier><identifier>DOI: 10.3390/jcm11247391</identifier><identifier>PMID: 36556007</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Clinical medicine ; Dysphagia ; Expenditures ; Hospitals ; Intubation ; Mortality ; Normal distribution ; Observational studies ; Ostomy ; Patients ; Pneumonia ; Regression analysis ; Software ; Swallowing ; Therapy ; Tracheotomy ; Ventilators</subject><ispartof>Journal of clinical medicine, 2022-12, Vol.11 (24), p.7391</ispartof><rights>2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2022 by the authors. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c409t-25e6925329d534e322f03fe44e5602b8fe008ebdaeaec2074a1a6ff134ef78543</citedby><cites>FETCH-LOGICAL-c409t-25e6925329d534e322f03fe44e5602b8fe008ebdaeaec2074a1a6ff134ef78543</cites><orcidid>0000-0001-9878-201X ; 0000-0002-2344-0231 ; 0000-0003-4849-5228 ; 0000-0001-5762-0559 ; 0000-0002-9694-5409</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785512/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785512/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36556007$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yoo, Wanho</creatorcontrib><creatorcontrib>Jang, Myung Hun</creatorcontrib><creatorcontrib>Kim, Sang Hun</creatorcontrib><creatorcontrib>Yoon, Jin A</creatorcontrib><creatorcontrib>Jang, Hyojin</creatorcontrib><creatorcontrib>Kim, Soohan</creatorcontrib><creatorcontrib>Lee, Kwangha</creatorcontrib><title>A Predictive Model for Dysphagia after Ventilator Liberation in Severe Pneumonia Patients Receiving Tracheostomy: A Single-Center, Observational Study</title><title>Journal of clinical medicine</title><addtitle>J Clin Med</addtitle><description>The main purpose of this study was to develop a model predictive of dysphagia in hospital survivors with severe pneumonia who underwent tracheostomy during their hospital stay. The present study included 175 patients (72% male; mean age, 71.3 years) over 5 years. None of these patients had a history of deglutition disorder before hospital admission. Binary logistic regression analysis was performed to identify factors predicting dysphagia at hospital discharge. Dysphagia scores were calculated from β-coefficients and by assigning points to variables. Of the enrolled patients, 105 (60%) had dysphagia at hospital discharge. Factors prognostic of dysphagia at hospital discharge included being underweight (body mass index < 18.5 kg/m2), non-participation in a dysphagia therapy program, mechanical ventilation ≥ 15 days, age ≥ 74 years, and chronic neurologic diseases. Underweight and non-participation in a dysphagia therapy program were assigned +2 points and the other factors were assigned +1 point. Dysphagia scores showed acceptable discrimination (area under the receiver operating characteristic curve for dysphagia 0.819, 95% confidence interval: 0.754−0.873, p < 0.001) and calibration (Hosmer−Lemeshow chi-square = 9.585, with df 7 and p = 0.213). The developed dysphagia score was predictive of deglutition disorder at hospital discharge in tracheostomized patients with severe pneumonia.</description><subject>Clinical medicine</subject><subject>Dysphagia</subject><subject>Expenditures</subject><subject>Hospitals</subject><subject>Intubation</subject><subject>Mortality</subject><subject>Normal distribution</subject><subject>Observational studies</subject><subject>Ostomy</subject><subject>Patients</subject><subject>Pneumonia</subject><subject>Regression analysis</subject><subject>Software</subject><subject>Swallowing</subject><subject>Therapy</subject><subject>Tracheotomy</subject><subject>Ventilators</subject><issn>2077-0383</issn><issn>2077-0383</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpdkV2L1DAYhYMo7rLulfcS8EbQar7aNF4Iw_gJIzs4q7clTd_MZGibMUkL80f8vcbddRnNTULOk8N7chB6SslrzhV5szcDpUxIrugDdM6IlAXhNX94cj5DlzHuSV51LRiVj9EZr8qyIkSeo18LvA7QOZPcDPir76DH1gf8_hgPO711GmubIOAfMCbX65SllWsh6OT8iN2INzBDALweYRr8mPl1ljIc8Tcw4GY3bvF10GYHPiY_HN_iBd7kyx6KZcYgvMJXbYQw3zjqHm_S1B2foEdW9xEu7_YL9P3jh-vl52J19enLcrEqjCAqFayESrGSM9WVXABnzBJuQQjI8VhbW8ihoe00aDD5Q4SmurKWZtbKuhT8Ar279T1M7QCdyRMF3TeH4AYdjo3XrvlXGd2u2fq5Ufl5SVk2eHFnEPzPCWJqBhcN9L0ewU-xYbKsiVKVJBl9_h-691PIkW-oSlJViSpTL28pE3yMAez9MJQ0fypvTirP9LPT-e_ZvwXz34odqXk</recordid><startdate>20221213</startdate><enddate>20221213</enddate><creator>Yoo, Wanho</creator><creator>Jang, Myung Hun</creator><creator>Kim, Sang Hun</creator><creator>Yoon, Jin A</creator><creator>Jang, Hyojin</creator><creator>Kim, Soohan</creator><creator>Lee, Kwangha</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>COVID</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-9878-201X</orcidid><orcidid>https://orcid.org/0000-0002-2344-0231</orcidid><orcidid>https://orcid.org/0000-0003-4849-5228</orcidid><orcidid>https://orcid.org/0000-0001-5762-0559</orcidid><orcidid>https://orcid.org/0000-0002-9694-5409</orcidid></search><sort><creationdate>20221213</creationdate><title>A Predictive Model for Dysphagia after Ventilator Liberation in Severe Pneumonia Patients Receiving Tracheostomy: A Single-Center, Observational Study</title><author>Yoo, Wanho ; Jang, Myung Hun ; Kim, Sang Hun ; Yoon, Jin A ; Jang, Hyojin ; Kim, Soohan ; Lee, Kwangha</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c409t-25e6925329d534e322f03fe44e5602b8fe008ebdaeaec2074a1a6ff134ef78543</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Clinical medicine</topic><topic>Dysphagia</topic><topic>Expenditures</topic><topic>Hospitals</topic><topic>Intubation</topic><topic>Mortality</topic><topic>Normal distribution</topic><topic>Observational studies</topic><topic>Ostomy</topic><topic>Patients</topic><topic>Pneumonia</topic><topic>Regression analysis</topic><topic>Software</topic><topic>Swallowing</topic><topic>Therapy</topic><topic>Tracheotomy</topic><topic>Ventilators</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yoo, Wanho</creatorcontrib><creatorcontrib>Jang, Myung Hun</creatorcontrib><creatorcontrib>Kim, Sang Hun</creatorcontrib><creatorcontrib>Yoon, Jin A</creatorcontrib><creatorcontrib>Jang, Hyojin</creatorcontrib><creatorcontrib>Kim, Soohan</creatorcontrib><creatorcontrib>Lee, Kwangha</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Coronavirus Research Database</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of clinical medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yoo, Wanho</au><au>Jang, Myung Hun</au><au>Kim, Sang Hun</au><au>Yoon, Jin A</au><au>Jang, Hyojin</au><au>Kim, Soohan</au><au>Lee, Kwangha</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Predictive Model for Dysphagia after Ventilator Liberation in Severe Pneumonia Patients Receiving Tracheostomy: A Single-Center, Observational Study</atitle><jtitle>Journal of clinical medicine</jtitle><addtitle>J Clin Med</addtitle><date>2022-12-13</date><risdate>2022</risdate><volume>11</volume><issue>24</issue><spage>7391</spage><pages>7391-</pages><issn>2077-0383</issn><eissn>2077-0383</eissn><abstract>The main purpose of this study was to develop a model predictive of dysphagia in hospital survivors with severe pneumonia who underwent tracheostomy during their hospital stay. The present study included 175 patients (72% male; mean age, 71.3 years) over 5 years. None of these patients had a history of deglutition disorder before hospital admission. Binary logistic regression analysis was performed to identify factors predicting dysphagia at hospital discharge. Dysphagia scores were calculated from β-coefficients and by assigning points to variables. Of the enrolled patients, 105 (60%) had dysphagia at hospital discharge. Factors prognostic of dysphagia at hospital discharge included being underweight (body mass index < 18.5 kg/m2), non-participation in a dysphagia therapy program, mechanical ventilation ≥ 15 days, age ≥ 74 years, and chronic neurologic diseases. Underweight and non-participation in a dysphagia therapy program were assigned +2 points and the other factors were assigned +1 point. 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subjects | Clinical medicine Dysphagia Expenditures Hospitals Intubation Mortality Normal distribution Observational studies Ostomy Patients Pneumonia Regression analysis Software Swallowing Therapy Tracheotomy Ventilators |
title | A Predictive Model for Dysphagia after Ventilator Liberation in Severe Pneumonia Patients Receiving Tracheostomy: A Single-Center, Observational Study |
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