Reduced Opioid Consumption with Pericapsular Nerve Group Block for Hip Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial
The pericapsular nerve group (PENG) block targets the nerves innervating the anterior hip surface; however, few studies on this technique are currently available. We investigated the effects of the PENG block on postoperative opioid consumption after a hip surgery. This was a randomized, double-blin...
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| creator | Chung, Chan Jong Eom, Deuk Won Lee, Tae Young Park, Sang Yoong |
| description | The pericapsular nerve group (PENG) block targets the nerves innervating the anterior hip surface; however, few studies on this technique are currently available. We investigated the effects of the PENG block on postoperative opioid consumption after a hip surgery. This was a randomized, double-blind, placebo-controlled study conducted at a single institution. Fifty patients undergoing hip surgery were randomly allocated, 25 in each group, to receive a PENG block either using 25 mL of 0.5% ropivacaine (PENG group) or 25 mL of saline (control group). The primary outcome was the total opioid consumption 24 h postoperatively. The secondary outcomes were postoperative pain scores, time to first opioid demand, sensory block efficiency, quadriceps muscle strength, complications, and patient satisfaction. Compared with those in the control group, patients in the PENG group had a significantly lower total opioid consumption 24 h postoperatively (440.72 ± 242.20 μg vs. 611.07 ± 313.89 μg, P = 0.037) and significantly lower pain scores at 30 min postblock and 6 postoperatively (P |
| doi_str_mv | 10.1155/2022/6022380 |
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We investigated the effects of the PENG block on postoperative opioid consumption after a hip surgery. This was a randomized, double-blind, placebo-controlled study conducted at a single institution. Fifty patients undergoing hip surgery were randomly allocated, 25 in each group, to receive a PENG block either using 25 mL of 0.5% ropivacaine (PENG group) or 25 mL of saline (control group). The primary outcome was the total opioid consumption 24 h postoperatively. The secondary outcomes were postoperative pain scores, time to first opioid demand, sensory block efficiency, quadriceps muscle strength, complications, and patient satisfaction. Compared with those in the control group, patients in the PENG group had a significantly lower total opioid consumption 24 h postoperatively (440.72 ± 242.20 μg vs. 611.07 ± 313.89 μg, P = 0.037) and significantly lower pain scores at 30 min postblock and 6 postoperatively (P<0.001 and P<0.001, respectively). The time to first opioid demand was significantly shorter in the control group than in the PENG group P<0.001. Sensory block effectiveness was better in the PENG group 30 min postblock and 6 and 12 h postoperatively than in the control group. Patient satisfaction was also better in the PENG group than in the control group. There were no differences in the other outcomes. The PENG block reduced the total opioid consumption in the first 24 h after hip surgery with no significant effects on quadriceps muscle strength and complication rate. This study was registered at the Korea Clinical Research Information Service (cris.nih.go.kr; Reg. No. KCT0006348) on July 16, 2021.</description><identifier>ISSN: 1203-6765</identifier><identifier>EISSN: 1918-1523</identifier><identifier>DOI: 10.1155/2022/6022380</identifier><identifier>PMID: 36569462</identifier><language>eng</language><publisher>United States: Hindawi</publisher><subject>Analgesics ; Analgesics, Opioid - therapeutic use ; Double-Blind Method ; Double-blind studies ; Femoral Nerve ; Fentanyl ; Fracture fixation ; Fractures ; General anesthesia ; Hip joint ; Humans ; Medical personnel ; Medical research ; Medicine, Experimental ; Narcotics ; Nerve block ; Nerve Block - methods ; Opioids ; Pain ; Pain, Postoperative - drug therapy ; Pain, Postoperative - etiology ; Patient satisfaction ; Physiological aspects ; Ropivacaine ; Surgery ; Testing ; Ultrasonic imaging</subject><ispartof>Pain Research and Management, 2022-12, Vol.2022, p.6022380-10</ispartof><rights>Copyright © 2022 Chan Jong Chung et al.</rights><rights>COPYRIGHT 2022 John Wiley & Sons, Inc.</rights><rights>Copyright © 2022 Chan Jong Chung et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2022 Chan Jong Chung et al. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c612t-c1a2b49716e1f8b6b8c766108ded02078452ef7a469f2b2c3482c3168f77a8363</citedby><cites>FETCH-LOGICAL-c612t-c1a2b49716e1f8b6b8c766108ded02078452ef7a469f2b2c3482c3168f77a8363</cites><orcidid>0000-0002-0919-1398 ; 0000-0002-9241-9735 ; 0000-0002-0236-7135 ; 0000-0001-7495-8025</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780006/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780006/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,865,878,886,27929,27930,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36569462$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Rakhshan, Vahid</contributor><contributor>Vahid Rakhshan</contributor><creatorcontrib>Chung, Chan Jong</creatorcontrib><creatorcontrib>Eom, Deuk Won</creatorcontrib><creatorcontrib>Lee, Tae Young</creatorcontrib><creatorcontrib>Park, Sang Yoong</creatorcontrib><title>Reduced Opioid Consumption with Pericapsular Nerve Group Block for Hip Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial</title><title>Pain Research and Management</title><addtitle>Pain Res Manag</addtitle><description>The pericapsular nerve group (PENG) block targets the nerves innervating the anterior hip surface; however, few studies on this technique are currently available. We investigated the effects of the PENG block on postoperative opioid consumption after a hip surgery. This was a randomized, double-blind, placebo-controlled study conducted at a single institution. Fifty patients undergoing hip surgery were randomly allocated, 25 in each group, to receive a PENG block either using 25 mL of 0.5% ropivacaine (PENG group) or 25 mL of saline (control group). The primary outcome was the total opioid consumption 24 h postoperatively. The secondary outcomes were postoperative pain scores, time to first opioid demand, sensory block efficiency, quadriceps muscle strength, complications, and patient satisfaction. Compared with those in the control group, patients in the PENG group had a significantly lower total opioid consumption 24 h postoperatively (440.72 ± 242.20 μg vs. 611.07 ± 313.89 μg, P = 0.037) and significantly lower pain scores at 30 min postblock and 6 postoperatively (P<0.001 and P<0.001, respectively). The time to first opioid demand was significantly shorter in the control group than in the PENG group P<0.001. Sensory block effectiveness was better in the PENG group 30 min postblock and 6 and 12 h postoperatively than in the control group. Patient satisfaction was also better in the PENG group than in the control group. There were no differences in the other outcomes. The PENG block reduced the total opioid consumption in the first 24 h after hip surgery with no significant effects on quadriceps muscle strength and complication rate. This study was registered at the Korea Clinical Research Information Service (cris.nih.go.kr; Reg. 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Eom, Deuk Won ; Lee, Tae Young ; Park, Sang Yoong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c612t-c1a2b49716e1f8b6b8c766108ded02078452ef7a469f2b2c3482c3168f77a8363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Analgesics</topic><topic>Analgesics, Opioid - therapeutic use</topic><topic>Double-Blind Method</topic><topic>Double-blind studies</topic><topic>Femoral Nerve</topic><topic>Fentanyl</topic><topic>Fracture fixation</topic><topic>Fractures</topic><topic>General anesthesia</topic><topic>Hip joint</topic><topic>Humans</topic><topic>Medical personnel</topic><topic>Medical research</topic><topic>Medicine, Experimental</topic><topic>Narcotics</topic><topic>Nerve block</topic><topic>Nerve Block - methods</topic><topic>Opioids</topic><topic>Pain</topic><topic>Pain, Postoperative - drug therapy</topic><topic>Pain, Postoperative - etiology</topic><topic>Patient satisfaction</topic><topic>Physiological aspects</topic><topic>Ropivacaine</topic><topic>Surgery</topic><topic>Testing</topic><topic>Ultrasonic imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chung, Chan Jong</creatorcontrib><creatorcontrib>Eom, Deuk Won</creatorcontrib><creatorcontrib>Lee, Tae Young</creatorcontrib><creatorcontrib>Park, Sang Yoong</creatorcontrib><collection>Hindawi Publishing Complete</collection><collection>Hindawi Publishing Subscription Journals</collection><collection>Hindawi Publishing Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Docstoc</collection><collection>University Readers</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Canadian Business & Current Affairs Database</collection><collection>Canadian Business & Current Affairs Database (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>CBCA Reference & Current Events</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Pain Research and Management</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chung, Chan Jong</au><au>Eom, Deuk Won</au><au>Lee, Tae Young</au><au>Park, Sang Yoong</au><au>Rakhshan, Vahid</au><au>Vahid Rakhshan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reduced Opioid Consumption with Pericapsular Nerve Group Block for Hip Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial</atitle><jtitle>Pain Research and Management</jtitle><addtitle>Pain Res Manag</addtitle><date>2022-12-15</date><risdate>2022</risdate><volume>2022</volume><spage>6022380</spage><epage>10</epage><pages>6022380-10</pages><issn>1203-6765</issn><eissn>1918-1523</eissn><abstract>The pericapsular nerve group (PENG) block targets the nerves innervating the anterior hip surface; however, few studies on this technique are currently available. We investigated the effects of the PENG block on postoperative opioid consumption after a hip surgery. This was a randomized, double-blind, placebo-controlled study conducted at a single institution. Fifty patients undergoing hip surgery were randomly allocated, 25 in each group, to receive a PENG block either using 25 mL of 0.5% ropivacaine (PENG group) or 25 mL of saline (control group). The primary outcome was the total opioid consumption 24 h postoperatively. The secondary outcomes were postoperative pain scores, time to first opioid demand, sensory block efficiency, quadriceps muscle strength, complications, and patient satisfaction. Compared with those in the control group, patients in the PENG group had a significantly lower total opioid consumption 24 h postoperatively (440.72 ± 242.20 μg vs. 611.07 ± 313.89 μg, P = 0.037) and significantly lower pain scores at 30 min postblock and 6 postoperatively (P<0.001 and P<0.001, respectively). The time to first opioid demand was significantly shorter in the control group than in the PENG group P<0.001. Sensory block effectiveness was better in the PENG group 30 min postblock and 6 and 12 h postoperatively than in the control group. Patient satisfaction was also better in the PENG group than in the control group. There were no differences in the other outcomes. The PENG block reduced the total opioid consumption in the first 24 h after hip surgery with no significant effects on quadriceps muscle strength and complication rate. This study was registered at the Korea Clinical Research Information Service (cris.nih.go.kr; Reg. No. KCT0006348) on July 16, 2021.</abstract><cop>United States</cop><pub>Hindawi</pub><pmid>36569462</pmid><doi>10.1155/2022/6022380</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0002-0919-1398</orcidid><orcidid>https://orcid.org/0000-0002-9241-9735</orcidid><orcidid>https://orcid.org/0000-0002-0236-7135</orcidid><orcidid>https://orcid.org/0000-0001-7495-8025</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Analgesics Analgesics, Opioid - therapeutic use Double-Blind Method Double-blind studies Femoral Nerve Fentanyl Fracture fixation Fractures General anesthesia Hip joint Humans Medical personnel Medical research Medicine, Experimental Narcotics Nerve block Nerve Block - methods Opioids Pain Pain, Postoperative - drug therapy Pain, Postoperative - etiology Patient satisfaction Physiological aspects Ropivacaine Surgery Testing Ultrasonic imaging |
| title | Reduced Opioid Consumption with Pericapsular Nerve Group Block for Hip Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial |
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