A New Transgenic Tool to Study the Ret Signaling Pathway in the Enteric Nervous System

The receptor tyrosine kinase Ret plays a critical role in regulating enteric nervous system (ENS) development. Ret is important for proliferation, migration, and survival of enteric progenitor cells (EPCs). Ret also promotes neuronal fate, but its role during neuronal differentiation and in the adul...

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Veröffentlicht in:	International journal of molecular sciences 2022-12, Vol.23 (24), p.15667
Hauptverfasser:	Bandla, Ashoka, Melancon, Ellie, Taylor, Charlotte R, Davidson, Ann E, Eisen, Judith S, Ganz, Julia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adults Animals Animals, Genetically Modified Cell proliferation Cells (biology) Cloning Danio rerio Embryos Enteric nervous system Enteric Nervous System - metabolism Female Hirschsprung's disease Humans Hypotheses Kinases Male Mutation Nervous system Neural stem cells Neurons Phenotypes Progenitor cells Protein-tyrosine kinase receptors Proteins Proto-Oncogene Proteins c-ret - genetics Proto-Oncogene Proteins c-ret - metabolism Ret protein Signal Transduction Sox10 protein Tyrosine Zebrafish Zebrafish - genetics Zebrafish - metabolism
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