A Comparison between Open and Minimally Invasive Techniques for the Resection of Colorectal Liver Metastasis
The liver is the most common site of colorectal cancer metastasis. Liver surgery is a cornerstone in treatment, with progressive expansion of minimally invasive surgery (MIS). This study aims to compare short- and long-term outcomes of open surgery and MIS for the treatment of colorectal adenocarcin...
Gespeichert in:
| Veröffentlicht in: | Healthcare (Basel) 2022-12, Vol.10 (12), p.2433 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 12 |
| container_start_page | 2433 |
| container_title | Healthcare (Basel) |
| container_volume | 10 |
| creator | Bartolini, Ilenia Fortuna, Laura Risaliti, Matteo Tirloni, Luca Buccianti, Simone Luceri, Cristina Ringressi, Maria Novella Batignani, Giacomo Taddei, Antonio |
| description | The liver is the most common site of colorectal cancer metastasis. Liver surgery is a cornerstone in treatment, with progressive expansion of minimally invasive surgery (MIS). This study aims to compare short- and long-term outcomes of open surgery and MIS for the treatment of colorectal adenocarcinoma liver metastasis during the first three years of increasing caseload and implementation of MIS use in liver surgery. All patients treated between November 2018 and August 2021 at Careggi Teaching Hospital in Florence, Italy, were prospectively entered into a database and retrospectively reviewed. Fifty-one patients were resected (41 open, 10 MIS). Considering that patients with a significantly higher number of lesions underwent open surgery and operative results were similar, postoperative morbidity rate and length of hospital stay were significantly higher in the open group. No differences were found in the pathological specimen. The postoperative mortality rate was 2%. Mean overall survival and disease-free survival were 46 months (95% CI 42-50) and 22 months (95% CI 15.6-29), respectively. The use of minimally invasive techniques in liver surgery is safe and feasible if surgeons have adequate expertise. MIS and parenchymal sparing resections should be preferred whenever technically feasible. |
| doi_str_mv | 10.3390/healthcare10122433 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9778157</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A744639498</galeid><sourcerecordid>A744639498</sourcerecordid><originalsourceid>FETCH-LOGICAL-c448t-840ba899603f30e1824540694accff43d6215df47bd0bccb76cc1d9e527c18103</originalsourceid><addsrcrecordid>eNptkltLHDEYhodSqWL9A16UQG96szanmSQ3hWXpQVgRRK9DJvPFiWSSbTK74r9vFq3VtpMhx-d9wxu-pjkl-IwxhT-PYMI8WpOBYEIpZ-xNc0QpFQuFGX37Yn7YnJRyh-unCJOsfdccsq5tmWrFUROWaJWmjcm-pIh6mO8BIrrc1M7EAV346CcTwgM6jztT_A7QNdgx-p9bKMiljOYR0BUUsLOvBslVu5ByXZqA1pXP6AJmU-rvy_vmwJlQ4ORpPG5uvn29Xv1YrC-_n6-W64XlXM4LyXFvpFIdZo5hIJLyluNOcWOtc5wNHSXt4LjoB9xb24vOWjIoaKmwRBLMjpsvj76bbT_BYCHO2QS9yTVLftDJeP36JPpR36adVkJI0opq8OnJIKd90llPvlgIwURI26KpaCUhXNGuoh__Qu_SNscab091nVRUkj_UrQmgfXSp3mv3pnopOO-Y4kpW6uw_VG0DTN6mCM7X_VcC-iiwOZWSwT1nJFjvy0T_WyZV9OHl6zxLfhcF-wVjarrR</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2756689281</pqid></control><display><type>article</type><title>A Comparison between Open and Minimally Invasive Techniques for the Resection of Colorectal Liver Metastasis</title><source>PubMed Central Open Access</source><source>MDPI - Multidisciplinary Digital Publishing Institute</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Bartolini, Ilenia ; Fortuna, Laura ; Risaliti, Matteo ; Tirloni, Luca ; Buccianti, Simone ; Luceri, Cristina ; Ringressi, Maria Novella ; Batignani, Giacomo ; Taddei, Antonio</creator><creatorcontrib>Bartolini, Ilenia ; Fortuna, Laura ; Risaliti, Matteo ; Tirloni, Luca ; Buccianti, Simone ; Luceri, Cristina ; Ringressi, Maria Novella ; Batignani, Giacomo ; Taddei, Antonio</creatorcontrib><description>The liver is the most common site of colorectal cancer metastasis. Liver surgery is a cornerstone in treatment, with progressive expansion of minimally invasive surgery (MIS). This study aims to compare short- and long-term outcomes of open surgery and MIS for the treatment of colorectal adenocarcinoma liver metastasis during the first three years of increasing caseload and implementation of MIS use in liver surgery. All patients treated between November 2018 and August 2021 at Careggi Teaching Hospital in Florence, Italy, were prospectively entered into a database and retrospectively reviewed. Fifty-one patients were resected (41 open, 10 MIS). Considering that patients with a significantly higher number of lesions underwent open surgery and operative results were similar, postoperative morbidity rate and length of hospital stay were significantly higher in the open group. No differences were found in the pathological specimen. The postoperative mortality rate was 2%. Mean overall survival and disease-free survival were 46 months (95% CI 42-50) and 22 months (95% CI 15.6-29), respectively. The use of minimally invasive techniques in liver surgery is safe and feasible if surgeons have adequate expertise. MIS and parenchymal sparing resections should be preferred whenever technically feasible.</description><identifier>ISSN: 2227-9032</identifier><identifier>EISSN: 2227-9032</identifier><identifier>DOI: 10.3390/healthcare10122433</identifier><identifier>PMID: 36553957</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Abdomen ; Abdominal surgery ; Antigens ; Body mass index ; Cancer therapies ; Care and treatment ; Chemotherapy ; Colorectal cancer ; Colorectal surgery ; Hepatectomy ; Hospitals ; Laparoscopy ; Liver ; Liver cancer ; Metastasis ; Minimally invasive surgery ; Mortality ; Patient outcomes ; Patients ; Radiation therapy ; Robotics ; Tomography</subject><ispartof>Healthcare (Basel), 2022-12, Vol.10 (12), p.2433</ispartof><rights>COPYRIGHT 2022 MDPI AG</rights><rights>2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2022 by the authors. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c448t-840ba899603f30e1824540694accff43d6215df47bd0bccb76cc1d9e527c18103</cites><orcidid>0000-0003-0387-2042 ; 0000-0003-0624-7445 ; 0000-0003-1232-8778 ; 0000-0003-2963-4085 ; 0000-0001-8476-2536 ; 0000-0001-8369-6418</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778157/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778157/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36553957$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bartolini, Ilenia</creatorcontrib><creatorcontrib>Fortuna, Laura</creatorcontrib><creatorcontrib>Risaliti, Matteo</creatorcontrib><creatorcontrib>Tirloni, Luca</creatorcontrib><creatorcontrib>Buccianti, Simone</creatorcontrib><creatorcontrib>Luceri, Cristina</creatorcontrib><creatorcontrib>Ringressi, Maria Novella</creatorcontrib><creatorcontrib>Batignani, Giacomo</creatorcontrib><creatorcontrib>Taddei, Antonio</creatorcontrib><title>A Comparison between Open and Minimally Invasive Techniques for the Resection of Colorectal Liver Metastasis</title><title>Healthcare (Basel)</title><addtitle>Healthcare (Basel)</addtitle><description>The liver is the most common site of colorectal cancer metastasis. Liver surgery is a cornerstone in treatment, with progressive expansion of minimally invasive surgery (MIS). This study aims to compare short- and long-term outcomes of open surgery and MIS for the treatment of colorectal adenocarcinoma liver metastasis during the first three years of increasing caseload and implementation of MIS use in liver surgery. All patients treated between November 2018 and August 2021 at Careggi Teaching Hospital in Florence, Italy, were prospectively entered into a database and retrospectively reviewed. Fifty-one patients were resected (41 open, 10 MIS). Considering that patients with a significantly higher number of lesions underwent open surgery and operative results were similar, postoperative morbidity rate and length of hospital stay were significantly higher in the open group. No differences were found in the pathological specimen. The postoperative mortality rate was 2%. Mean overall survival and disease-free survival were 46 months (95% CI 42-50) and 22 months (95% CI 15.6-29), respectively. The use of minimally invasive techniques in liver surgery is safe and feasible if surgeons have adequate expertise. MIS and parenchymal sparing resections should be preferred whenever technically feasible.</description><subject>Abdomen</subject><subject>Abdominal surgery</subject><subject>Antigens</subject><subject>Body mass index</subject><subject>Cancer therapies</subject><subject>Care and treatment</subject><subject>Chemotherapy</subject><subject>Colorectal cancer</subject><subject>Colorectal surgery</subject><subject>Hepatectomy</subject><subject>Hospitals</subject><subject>Laparoscopy</subject><subject>Liver</subject><subject>Liver cancer</subject><subject>Metastasis</subject><subject>Minimally invasive surgery</subject><subject>Mortality</subject><subject>Patient outcomes</subject><subject>Patients</subject><subject>Radiation therapy</subject><subject>Robotics</subject><subject>Tomography</subject><issn>2227-9032</issn><issn>2227-9032</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkltLHDEYhodSqWL9A16UQG96szanmSQ3hWXpQVgRRK9DJvPFiWSSbTK74r9vFq3VtpMhx-d9wxu-pjkl-IwxhT-PYMI8WpOBYEIpZ-xNc0QpFQuFGX37Yn7YnJRyh-unCJOsfdccsq5tmWrFUROWaJWmjcm-pIh6mO8BIrrc1M7EAV346CcTwgM6jztT_A7QNdgx-p9bKMiljOYR0BUUsLOvBslVu5ByXZqA1pXP6AJmU-rvy_vmwJlQ4ORpPG5uvn29Xv1YrC-_n6-W64XlXM4LyXFvpFIdZo5hIJLyluNOcWOtc5wNHSXt4LjoB9xb24vOWjIoaKmwRBLMjpsvj76bbT_BYCHO2QS9yTVLftDJeP36JPpR36adVkJI0opq8OnJIKd90llPvlgIwURI26KpaCUhXNGuoh__Qu_SNscab091nVRUkj_UrQmgfXSp3mv3pnopOO-Y4kpW6uw_VG0DTN6mCM7X_VcC-iiwOZWSwT1nJFjvy0T_WyZV9OHl6zxLfhcF-wVjarrR</recordid><startdate>20221202</startdate><enddate>20221202</enddate><creator>Bartolini, Ilenia</creator><creator>Fortuna, Laura</creator><creator>Risaliti, Matteo</creator><creator>Tirloni, Luca</creator><creator>Buccianti, Simone</creator><creator>Luceri, Cristina</creator><creator>Ringressi, Maria Novella</creator><creator>Batignani, Giacomo</creator><creator>Taddei, Antonio</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7XB</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>KB0</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-0387-2042</orcidid><orcidid>https://orcid.org/0000-0003-0624-7445</orcidid><orcidid>https://orcid.org/0000-0003-1232-8778</orcidid><orcidid>https://orcid.org/0000-0003-2963-4085</orcidid><orcidid>https://orcid.org/0000-0001-8476-2536</orcidid><orcidid>https://orcid.org/0000-0001-8369-6418</orcidid></search><sort><creationdate>20221202</creationdate><title>A Comparison between Open and Minimally Invasive Techniques for the Resection of Colorectal Liver Metastasis</title><author>Bartolini, Ilenia ; Fortuna, Laura ; Risaliti, Matteo ; Tirloni, Luca ; Buccianti, Simone ; Luceri, Cristina ; Ringressi, Maria Novella ; Batignani, Giacomo ; Taddei, Antonio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c448t-840ba899603f30e1824540694accff43d6215df47bd0bccb76cc1d9e527c18103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Abdomen</topic><topic>Abdominal surgery</topic><topic>Antigens</topic><topic>Body mass index</topic><topic>Cancer therapies</topic><topic>Care and treatment</topic><topic>Chemotherapy</topic><topic>Colorectal cancer</topic><topic>Colorectal surgery</topic><topic>Hepatectomy</topic><topic>Hospitals</topic><topic>Laparoscopy</topic><topic>Liver</topic><topic>Liver cancer</topic><topic>Metastasis</topic><topic>Minimally invasive surgery</topic><topic>Mortality</topic><topic>Patient outcomes</topic><topic>Patients</topic><topic>Radiation therapy</topic><topic>Robotics</topic><topic>Tomography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bartolini, Ilenia</creatorcontrib><creatorcontrib>Fortuna, Laura</creatorcontrib><creatorcontrib>Risaliti, Matteo</creatorcontrib><creatorcontrib>Tirloni, Luca</creatorcontrib><creatorcontrib>Buccianti, Simone</creatorcontrib><creatorcontrib>Luceri, Cristina</creatorcontrib><creatorcontrib>Ringressi, Maria Novella</creatorcontrib><creatorcontrib>Batignani, Giacomo</creatorcontrib><creatorcontrib>Taddei, Antonio</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Healthcare (Basel)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bartolini, Ilenia</au><au>Fortuna, Laura</au><au>Risaliti, Matteo</au><au>Tirloni, Luca</au><au>Buccianti, Simone</au><au>Luceri, Cristina</au><au>Ringressi, Maria Novella</au><au>Batignani, Giacomo</au><au>Taddei, Antonio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Comparison between Open and Minimally Invasive Techniques for the Resection of Colorectal Liver Metastasis</atitle><jtitle>Healthcare (Basel)</jtitle><addtitle>Healthcare (Basel)</addtitle><date>2022-12-02</date><risdate>2022</risdate><volume>10</volume><issue>12</issue><spage>2433</spage><pages>2433-</pages><issn>2227-9032</issn><eissn>2227-9032</eissn><abstract>The liver is the most common site of colorectal cancer metastasis. Liver surgery is a cornerstone in treatment, with progressive expansion of minimally invasive surgery (MIS). This study aims to compare short- and long-term outcomes of open surgery and MIS for the treatment of colorectal adenocarcinoma liver metastasis during the first three years of increasing caseload and implementation of MIS use in liver surgery. All patients treated between November 2018 and August 2021 at Careggi Teaching Hospital in Florence, Italy, were prospectively entered into a database and retrospectively reviewed. Fifty-one patients were resected (41 open, 10 MIS). Considering that patients with a significantly higher number of lesions underwent open surgery and operative results were similar, postoperative morbidity rate and length of hospital stay were significantly higher in the open group. No differences were found in the pathological specimen. The postoperative mortality rate was 2%. Mean overall survival and disease-free survival were 46 months (95% CI 42-50) and 22 months (95% CI 15.6-29), respectively. The use of minimally invasive techniques in liver surgery is safe and feasible if surgeons have adequate expertise. MIS and parenchymal sparing resections should be preferred whenever technically feasible.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>36553957</pmid><doi>10.3390/healthcare10122433</doi><orcidid>https://orcid.org/0000-0003-0387-2042</orcidid><orcidid>https://orcid.org/0000-0003-0624-7445</orcidid><orcidid>https://orcid.org/0000-0003-1232-8778</orcidid><orcidid>https://orcid.org/0000-0003-2963-4085</orcidid><orcidid>https://orcid.org/0000-0001-8476-2536</orcidid><orcidid>https://orcid.org/0000-0001-8369-6418</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2227-9032 |
| ispartof | Healthcare (Basel), 2022-12, Vol.10 (12), p.2433 |
| issn | 2227-9032 2227-9032 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9778157 |
| source | PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Abdomen Abdominal surgery Antigens Body mass index Cancer therapies Care and treatment Chemotherapy Colorectal cancer Colorectal surgery Hepatectomy Hospitals Laparoscopy Liver Liver cancer Metastasis Minimally invasive surgery Mortality Patient outcomes Patients Radiation therapy Robotics Tomography |
| title | A Comparison between Open and Minimally Invasive Techniques for the Resection of Colorectal Liver Metastasis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-13T09%3A59%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Comparison%20between%20Open%20and%20Minimally%20Invasive%20Techniques%20for%20the%20Resection%20of%20Colorectal%20Liver%20Metastasis&rft.jtitle=Healthcare%20(Basel)&rft.au=Bartolini,%20Ilenia&rft.date=2022-12-02&rft.volume=10&rft.issue=12&rft.spage=2433&rft.pages=2433-&rft.issn=2227-9032&rft.eissn=2227-9032&rft_id=info:doi/10.3390/healthcare10122433&rft_dat=%3Cgale_pubme%3EA744639498%3C/gale_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2756689281&rft_id=info:pmid/36553957&rft_galeid=A744639498&rfr_iscdi=true |