Novel 1,2,5-Trisubstituted Benzimidazoles Potentiate Apoptosis by Mitochondrial Dysfunction in Panel of Cancer Cells

Synthetic small molecules have been very effective in decimating cancer cells by targeting various aberrantly overexpressed oncogenic proteins. These small molecules target proteins involved in cell cycle regulation, cell division, migration, invasion, angiogenesis, and other regulatory proteins to...

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Veröffentlicht in:ACS omega 2022-12, Vol.7 (50), p.46955-46971
Hauptverfasser: Swathantraiah, Jagadeesha Gullahalli, Srinivasa, Sudhanva Muddenahalli, Belagal Motatis, Anil Kumar, Uttarkar, Akshay, Bettaswamygowda, Shwetha, Thimmaiah, Sridhar Bilgumba, Niranjan, Vidya, Rangappa, Shobith, Subbegowda, Rangappa Kanchugarakoppal, Ramegowda, Thimmegowda Naraganahalli
Format: Artikel
Sprache:eng
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