Safety and preliminary activity of pembrolizumab-carboplatin-paclitaxel in heavily pretreated and/or fragile patients with PDL1-positive recurrent/metastatic head and neck cancer

Novel chemo-immunotherapy (chemo-IO) combinations should be evaluated, which may be suitable for cisplatin-unfit or fluoropyrimide-ineligible patients with recurrent or metastatic squamous cell carcinoma of head and neck (R/M SCCHN) to guarantee higher and deeper responses than IO alone. The aim of...

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Veröffentlicht in:	Oncology letters 2023-01, Vol.25 (1), p.37, Article 37
Hauptverfasser:	Cabezas-Camarero, Santiago, Merino-Menéndez, Salomé, Cabrera-Martín, María Nieves, Sotelo, Miguel J, Plaza-Hernández, José Carlos, Falahat, Farzin, Iglesias-Moreno, María Cruz, Pérez-Segura, Pedro
Format:	Artikel
Sprache:	eng
Schlagworte:	Alopecia Angina pectoris Baldness Cancer Cancer therapies Carboplatin Cardiovascular disease Cell death Chemotherapy Comorbidity Head & neck cancer Head and neck cancer Heart failure Hepatitis Immunotherapy Medical imaging Medical research Medicine, Experimental Metastasis Monoclonal antibodies Oncology Patient compliance Squamous cell carcinoma Targeted cancer therapy Terminology
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