Central injection of abscisic acid attenuates mood disorders induced by subchronic stress in male mice
Stressful life increases the risk of mental and psychological disorders and cognitive deficits. Abscisic acid (ABA) is a plant hormone that has been recently discovered in mammalians. ABA is produced in response to stressful stimuli and it can reduce anxiety‐like behaviors and depression and improve...
Gespeichert in:
| Veröffentlicht in: | Brain and behavior 2022-12, Vol.12 (12), p.e2796-n/a |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | n/a |
|---|---|
| container_issue | 12 |
| container_start_page | e2796 |
| container_title | Brain and behavior |
| container_volume | 12 |
| creator | Shabani, Mohammad Ranjbar, Hoda Soti, Monavareh Naderi, Reyhaneh |
| description | Stressful life increases the risk of mental and psychological disorders and cognitive deficits. Abscisic acid (ABA) is a plant hormone that has been recently discovered in mammalians. ABA is produced in response to stressful stimuli and it can reduce anxiety‐like behaviors and depression and improve cognitive function. This study was designed to evaluate the effects of microinjection of ABA on depression, anxiety, passive avoidance learning and memory deficits induced by subchronic stress. ABA (10 and 15 μ$\umu $g/mouse, i.c.v.) was administered one week after recovery period for 4 consecutive days. A three‐session forced swimming test (FST) protocol for induction of subchronic stress was administered to the mice. Exploratory, anxiety‐like behavior, depression and cognitive function were assessed 24 h after the last swim stress session. The results indicated that ABA (15 μ$\umu $g/mouse) could ameliorate anxiety and depression induced by FST. In addition, ABA had no effect on the subchronic stress‐induced cognitive impairments. Taken together, the results suggest that ABA could improve anxiety and depression induced by subchronic stress. |
| doi_str_mv | 10.1002/brb3.2796 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9759152</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2755135843</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4436-d5828ffda0e9db1d9824924dc4e525b455a252129cb5df3b3b4a6ba754d475ab3</originalsourceid><addsrcrecordid>eNp1kU1LJDEQhsOysiPqYf_AEtjLehjtfFT39EXQQXcXBEH0HPJRvZOhu6NJtzL_3owzO6hgLkmopx6qeAn5zooTVhT81EQjTnhVl1_IPmcln4r8-frmPSFHKS2LfIBJLotvZCJKASBqtk-aOfZD1C31_RLt4ENPQ0O1SdYnb6m23lE9DNiPesBEuxAcdT6F6DCm3ORGi46aFU2jsYsY-tyUhohpXaSdbpF23uIh2Wt0m_Boex-Q-6vLu_mf6fXN77_z8-uplVKUUwczPmsapwusnWGunnFZc-msROBgJIDmwBmvrQHXCCOM1KXRFUgnK9BGHJCzjfdhNB06u1lOPUTf6bhSQXv1vtL7hfoXnlRdQc2AZ8GvrSCGxxHToDqfLLat7jGMSfFKAKsKwSGjPz-gyzDGPq-XKQAmYCZFpo43lI0hpYjNbhhWqHWAah2gWgeY2R9vp9-R_-PKwOkGePYtrj43qYvbC_GqfAFSY6Yy</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2755135843</pqid></control><display><type>article</type><title>Central injection of abscisic acid attenuates mood disorders induced by subchronic stress in male mice</title><source>MEDLINE</source><source>Wiley Online Library Journals</source><source>DOAJ Directory of Open Access Journals</source><source>Wiley Open Access</source><source>PubMed Central</source><source>EZB Electronic Journals Library</source><creator>Shabani, Mohammad ; Ranjbar, Hoda ; Soti, Monavareh ; Naderi, Reyhaneh</creator><creatorcontrib>Shabani, Mohammad ; Ranjbar, Hoda ; Soti, Monavareh ; Naderi, Reyhaneh</creatorcontrib><description>Stressful life increases the risk of mental and psychological disorders and cognitive deficits. Abscisic acid (ABA) is a plant hormone that has been recently discovered in mammalians. ABA is produced in response to stressful stimuli and it can reduce anxiety‐like behaviors and depression and improve cognitive function. This study was designed to evaluate the effects of microinjection of ABA on depression, anxiety, passive avoidance learning and memory deficits induced by subchronic stress. ABA (10 and 15 μ$\umu $g/mouse, i.c.v.) was administered one week after recovery period for 4 consecutive days. A three‐session forced swimming test (FST) protocol for induction of subchronic stress was administered to the mice. Exploratory, anxiety‐like behavior, depression and cognitive function were assessed 24 h after the last swim stress session. The results indicated that ABA (15 μ$\umu $g/mouse) could ameliorate anxiety and depression induced by FST. In addition, ABA had no effect on the subchronic stress‐induced cognitive impairments. Taken together, the results suggest that ABA could improve anxiety and depression induced by subchronic stress.</description><identifier>ISSN: 2162-3279</identifier><identifier>EISSN: 2162-3279</identifier><identifier>DOI: 10.1002/brb3.2796</identifier><identifier>PMID: 36355391</identifier><language>eng</language><publisher>United States: John Wiley & Sons, Inc</publisher><subject>Abscisic acid ; Abscisic Acid - pharmacology ; Animal cognition ; Animals ; Anxiety ; Anxiety - drug therapy ; Behavior ; Cognition ; Cognition Disorders ; cognitive impairments ; depression ; Depression - drug therapy ; Disease Models, Animal ; Drug dosages ; Mammals ; Mice ; Mood disorders ; Original ; Seeds ; Stress ; Stress, Psychological - complications ; Stress, Psychological - drug therapy ; Stress, Psychological - psychology ; Surgery ; swim stress ; Swimming ; Swimming - psychology</subject><ispartof>Brain and behavior, 2022-12, Vol.12 (12), p.e2796-n/a</ispartof><rights>2022 The Authors. published by Wiley Periodicals LLC.</rights><rights>2022 The Authors. Brain and Behavior published by Wiley Periodicals LLC.</rights><rights>2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4436-d5828ffda0e9db1d9824924dc4e525b455a252129cb5df3b3b4a6ba754d475ab3</citedby><cites>FETCH-LOGICAL-c4436-d5828ffda0e9db1d9824924dc4e525b455a252129cb5df3b3b4a6ba754d475ab3</cites><orcidid>0000-0002-2082-5849 ; 0000-0002-5428-4446</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759152/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759152/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,1416,11561,27923,27924,45573,45574,46051,46475,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36355391$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shabani, Mohammad</creatorcontrib><creatorcontrib>Ranjbar, Hoda</creatorcontrib><creatorcontrib>Soti, Monavareh</creatorcontrib><creatorcontrib>Naderi, Reyhaneh</creatorcontrib><title>Central injection of abscisic acid attenuates mood disorders induced by subchronic stress in male mice</title><title>Brain and behavior</title><addtitle>Brain Behav</addtitle><description>Stressful life increases the risk of mental and psychological disorders and cognitive deficits. Abscisic acid (ABA) is a plant hormone that has been recently discovered in mammalians. ABA is produced in response to stressful stimuli and it can reduce anxiety‐like behaviors and depression and improve cognitive function. This study was designed to evaluate the effects of microinjection of ABA on depression, anxiety, passive avoidance learning and memory deficits induced by subchronic stress. ABA (10 and 15 μ$\umu $g/mouse, i.c.v.) was administered one week after recovery period for 4 consecutive days. A three‐session forced swimming test (FST) protocol for induction of subchronic stress was administered to the mice. Exploratory, anxiety‐like behavior, depression and cognitive function were assessed 24 h after the last swim stress session. The results indicated that ABA (15 μ$\umu $g/mouse) could ameliorate anxiety and depression induced by FST. In addition, ABA had no effect on the subchronic stress‐induced cognitive impairments. Taken together, the results suggest that ABA could improve anxiety and depression induced by subchronic stress.</description><subject>Abscisic acid</subject><subject>Abscisic Acid - pharmacology</subject><subject>Animal cognition</subject><subject>Animals</subject><subject>Anxiety</subject><subject>Anxiety - drug therapy</subject><subject>Behavior</subject><subject>Cognition</subject><subject>Cognition Disorders</subject><subject>cognitive impairments</subject><subject>depression</subject><subject>Depression - drug therapy</subject><subject>Disease Models, Animal</subject><subject>Drug dosages</subject><subject>Mammals</subject><subject>Mice</subject><subject>Mood disorders</subject><subject>Original</subject><subject>Seeds</subject><subject>Stress</subject><subject>Stress, Psychological - complications</subject><subject>Stress, Psychological - drug therapy</subject><subject>Stress, Psychological - psychology</subject><subject>Surgery</subject><subject>swim stress</subject><subject>Swimming</subject><subject>Swimming - psychology</subject><issn>2162-3279</issn><issn>2162-3279</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>WIN</sourceid><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp1kU1LJDEQhsOysiPqYf_AEtjLehjtfFT39EXQQXcXBEH0HPJRvZOhu6NJtzL_3owzO6hgLkmopx6qeAn5zooTVhT81EQjTnhVl1_IPmcln4r8-frmPSFHKS2LfIBJLotvZCJKASBqtk-aOfZD1C31_RLt4ENPQ0O1SdYnb6m23lE9DNiPesBEuxAcdT6F6DCm3ORGi46aFU2jsYsY-tyUhohpXaSdbpF23uIh2Wt0m_Boex-Q-6vLu_mf6fXN77_z8-uplVKUUwczPmsapwusnWGunnFZc-msROBgJIDmwBmvrQHXCCOM1KXRFUgnK9BGHJCzjfdhNB06u1lOPUTf6bhSQXv1vtL7hfoXnlRdQc2AZ8GvrSCGxxHToDqfLLat7jGMSfFKAKsKwSGjPz-gyzDGPq-XKQAmYCZFpo43lI0hpYjNbhhWqHWAah2gWgeY2R9vp9-R_-PKwOkGePYtrj43qYvbC_GqfAFSY6Yy</recordid><startdate>202212</startdate><enddate>202212</enddate><creator>Shabani, Mohammad</creator><creator>Ranjbar, Hoda</creator><creator>Soti, Monavareh</creator><creator>Naderi, Reyhaneh</creator><general>John Wiley & Sons, Inc</general><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>WIN</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-2082-5849</orcidid><orcidid>https://orcid.org/0000-0002-5428-4446</orcidid></search><sort><creationdate>202212</creationdate><title>Central injection of abscisic acid attenuates mood disorders induced by subchronic stress in male mice</title><author>Shabani, Mohammad ; Ranjbar, Hoda ; Soti, Monavareh ; Naderi, Reyhaneh</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4436-d5828ffda0e9db1d9824924dc4e525b455a252129cb5df3b3b4a6ba754d475ab3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Abscisic acid</topic><topic>Abscisic Acid - pharmacology</topic><topic>Animal cognition</topic><topic>Animals</topic><topic>Anxiety</topic><topic>Anxiety - drug therapy</topic><topic>Behavior</topic><topic>Cognition</topic><topic>Cognition Disorders</topic><topic>cognitive impairments</topic><topic>depression</topic><topic>Depression - drug therapy</topic><topic>Disease Models, Animal</topic><topic>Drug dosages</topic><topic>Mammals</topic><topic>Mice</topic><topic>Mood disorders</topic><topic>Original</topic><topic>Seeds</topic><topic>Stress</topic><topic>Stress, Psychological - complications</topic><topic>Stress, Psychological - drug therapy</topic><topic>Stress, Psychological - psychology</topic><topic>Surgery</topic><topic>swim stress</topic><topic>Swimming</topic><topic>Swimming - psychology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shabani, Mohammad</creatorcontrib><creatorcontrib>Ranjbar, Hoda</creatorcontrib><creatorcontrib>Soti, Monavareh</creatorcontrib><creatorcontrib>Naderi, Reyhaneh</creatorcontrib><collection>Wiley Open Access</collection><collection>Wiley-Blackwell Open Access Backfiles (Open Access)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Psychology Database (ProQuest)</collection><collection>ProQuest research library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Brain and behavior</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shabani, Mohammad</au><au>Ranjbar, Hoda</au><au>Soti, Monavareh</au><au>Naderi, Reyhaneh</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Central injection of abscisic acid attenuates mood disorders induced by subchronic stress in male mice</atitle><jtitle>Brain and behavior</jtitle><addtitle>Brain Behav</addtitle><date>2022-12</date><risdate>2022</risdate><volume>12</volume><issue>12</issue><spage>e2796</spage><epage>n/a</epage><pages>e2796-n/a</pages><issn>2162-3279</issn><eissn>2162-3279</eissn><abstract>Stressful life increases the risk of mental and psychological disorders and cognitive deficits. Abscisic acid (ABA) is a plant hormone that has been recently discovered in mammalians. ABA is produced in response to stressful stimuli and it can reduce anxiety‐like behaviors and depression and improve cognitive function. This study was designed to evaluate the effects of microinjection of ABA on depression, anxiety, passive avoidance learning and memory deficits induced by subchronic stress. ABA (10 and 15 μ$\umu $g/mouse, i.c.v.) was administered one week after recovery period for 4 consecutive days. A three‐session forced swimming test (FST) protocol for induction of subchronic stress was administered to the mice. Exploratory, anxiety‐like behavior, depression and cognitive function were assessed 24 h after the last swim stress session. The results indicated that ABA (15 μ$\umu $g/mouse) could ameliorate anxiety and depression induced by FST. In addition, ABA had no effect on the subchronic stress‐induced cognitive impairments. Taken together, the results suggest that ABA could improve anxiety and depression induced by subchronic stress.</abstract><cop>United States</cop><pub>John Wiley & Sons, Inc</pub><pmid>36355391</pmid><doi>10.1002/brb3.2796</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-2082-5849</orcidid><orcidid>https://orcid.org/0000-0002-5428-4446</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2162-3279 |
| ispartof | Brain and behavior, 2022-12, Vol.12 (12), p.e2796-n/a |
| issn | 2162-3279 2162-3279 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9759152 |
| source | MEDLINE; Wiley Online Library Journals; DOAJ Directory of Open Access Journals; Wiley Open Access; PubMed Central; EZB Electronic Journals Library |
| subjects | Abscisic acid Abscisic Acid - pharmacology Animal cognition Animals Anxiety Anxiety - drug therapy Behavior Cognition Cognition Disorders cognitive impairments depression Depression - drug therapy Disease Models, Animal Drug dosages Mammals Mice Mood disorders Original Seeds Stress Stress, Psychological - complications Stress, Psychological - drug therapy Stress, Psychological - psychology Surgery swim stress Swimming Swimming - psychology |
| title | Central injection of abscisic acid attenuates mood disorders induced by subchronic stress in male mice |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T16%3A36%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Central%20injection%20of%20abscisic%20acid%20attenuates%20mood%20disorders%20induced%20by%20subchronic%20stress%20in%20male%20mice&rft.jtitle=Brain%20and%20behavior&rft.au=Shabani,%20Mohammad&rft.date=2022-12&rft.volume=12&rft.issue=12&rft.spage=e2796&rft.epage=n/a&rft.pages=e2796-n/a&rft.issn=2162-3279&rft.eissn=2162-3279&rft_id=info:doi/10.1002/brb3.2796&rft_dat=%3Cproquest_pubme%3E2755135843%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2755135843&rft_id=info:pmid/36355391&rfr_iscdi=true |