Recognition of 5-methyl-CG and CG base pairs in duplex DNA with high stability using antiparallel-type triplex-forming oligonucleotides with 2-guanidinoethyl-2'-deoxynebularine

The formation of triplex DNA is a site-specific recognition method that directly targets duplex DNA. However, triplex DNA formation is generally formed for the GC and AT base pairs of duplex DNA, and there are no natural nucleotides that recognize the CG and TA base pairs, or even the 5-methyl-CG (5...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nucleic acids research 2022-11, Vol.50 (21), p.12071-12081
Hauptverfasser:	Notomi, Ryotaro, Sasaki, Shigeki, Taniguchi, Yosuke
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Pairing Chemical Biology and Nucleic Acid Chemistry Deoxyribonucleosides DNA - genetics DNA - metabolism Humans Nucleic Acid Conformation Nucleosides Oligonucleotides
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!