Identification of Novel Kinases of Tau Using Fluorescence Complementation Mass Spectrometry (FCMS)

Hyperphosphorylation of the microtubule-associated protein Tau is a major hallmark of Alzheimer's disease and other tauopathies. Understanding the protein kinases that phosphorylate Tau is critical for the development of new drugs that target Tau phosphorylation. At present, the repertoire of t...

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Veröffentlicht in:	Molecular & cellular proteomics 2022-12, Vol.21 (12), p.100441-100441, Article 100441
Hauptverfasser:	Kao, Der-Shyang, Du, Yanyan, DeMarco, Andrew G, Min, Sehong, Hall, Mark C, Rochet, Jean-Christophe, Tao, W Andy
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - metabolism Humans Mass Spectrometry Phosphorylation Protein Kinases - metabolism Protein Serine-Threonine Kinases - metabolism Proteomics tau Proteins - genetics Technological Innovation and Resources
Online-Zugang:	Volltext
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