Ectopic CH60 mediates HAPLN1-induced cell survival signaling in multiple myeloma

Multiple myeloma (MM), the second most common hematological malignancy, is generally considered incurable because of the development of drug resistance. We previously reported that hyaluronan and proteoglycan link protein 1 (HAPLN1) produced by stromal cells induces activation of NF-κB, a tumor-supp...

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Veröffentlicht in:	Life science alliance 2023-03, Vol.6 (3), p.e202201636
Hauptverfasser:	De Bakshi, Debayan, Chen, Yu-Chia, Wuerzberger-Davis, Shelly M, Ma, Min, Waters, Bayley J, Li, Lingjun, Suzuki, Aussie, Miyamoto, Shigeki
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Survival Chaperonin 60 Humans Multiple Myeloma - genetics Multiple Myeloma - metabolism Multiple Myeloma - pathology NF-kappa B - metabolism Toll-Like Receptor 4
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