Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination

Several studies have shown that the pre-vaccination immune state is associated with the antibody response to vaccination. However, the generalizability and mechanisms that underlie this association remain poorly defined. Here, we sought to identify a common pre-vaccination signature and mechanisms t...

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Veröffentlicht in:Nature immunology 2022-12, Vol.23 (12), p.1777-1787
Hauptverfasser: Fourati, Slim, Tomalin, Lewis E., Mulè, Matthew P., Chawla, Daniel G., Gerritsen, Bram, Rychkov, Dmitry, Henrich, Evan, Miller, Helen E. R., Hagan, Thomas, Diray-Arce, Joann, Dunn, Patrick, Levy, Ofer, Gottardo, Raphael, Sarwal, Minnie M., Tsang, John S., Suárez-Fariñas, Mayte, Pulendran, Bali, Kleinstein, Steven H., Sékaly, Rafick-Pierre
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Sprache:eng
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