Letter to the editor: “Clinical characteristics, physiological features, and outcomes associated with hypercapnia in patients with acute hypoxemic respiratory failure due to COVID-19---insights from the PRoVENT-COVID study”
[...]lung protective ventilation using lower tidal volume and higher respiratory rate is the cornerstone of the management of patients with severe ARDS, including that attributable to Covid-19, with the potential consequence of hypercapnia. [...]ventilatory ratio, defined as [minute ventilation (ml/...
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| Veröffentlicht in: | Journal of critical care 2023-02, Vol.73, p.154177-154177, Article 154177 |
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| container_title | Journal of critical care |
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| creator | Bhattacharya, Dipasri Bhakta, Pradipta O'Brien, Brian Karim, Habib Md Reazaul Esquinas, Antonio M. |
| description | [...]lung protective ventilation using lower tidal volume and higher respiratory rate is the cornerstone of the management of patients with severe ARDS, including that attributable to Covid-19, with the potential consequence of hypercapnia. [...]ventilatory ratio, defined as [minute ventilation (ml/min) × partial pressure of arterial CO2 tension (mm Hg)]/(predicted body weight × 100 × 37.5), is a simple bedside index of assessing the efficiency of mechanical ventilation [6]. [...]hypoxemia, quantified by the ratio of partial pressure arterial oxygen tension and fraction of inspired oxygen concentration (PaO2/FiO2), does not necessarily assess the alveolar ventilation and physiological dead space which reflect the overall efficacy of the lungs to eliminate the CO2 load. |
| doi_str_mv | 10.1016/j.jcrc.2022.154177 |
| format | Article |
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[...]ventilatory ratio, defined as [minute ventilation (ml/min) × partial pressure of arterial CO2 tension (mm Hg)]/(predicted body weight × 100 × 37.5), is a simple bedside index of assessing the efficiency of mechanical ventilation [6]. 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[...]ventilatory ratio, defined as [minute ventilation (ml/min) × partial pressure of arterial CO2 tension (mm Hg)]/(predicted body weight × 100 × 37.5), is a simple bedside index of assessing the efficiency of mechanical ventilation [6]. [...]hypoxemia, quantified by the ratio of partial pressure arterial oxygen tension and fraction of inspired oxygen concentration (PaO2/FiO2), does not necessarily assess the alveolar ventilation and physiological dead space which reflect the overall efficacy of the lungs to eliminate the CO2 load.</description><subject>ARDS, lung protective ventilation</subject><subject>Carbon dioxide</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>Editing</subject><subject>Humans</subject><subject>Hypercapnia</subject><subject>Mortality</subject><subject>Outcomes</subject><subject>Physiology</subject><subject>Respiration, Artificial - adverse effects</subject><subject>Respiratory Distress Syndrome - etiology</subject><subject>Respiratory Distress Syndrome - therapy</subject><subject>Respiratory Insufficiency - etiology</subject><subject>Respiratory Insufficiency - therapy</subject><subject>Ventilation</subject><subject>Ventilators</subject><subject>Writing</subject><issn>0883-9441</issn><issn>1557-8615</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9ks1u1DAUhSMEokPhBVggS2xYkMGO7fygCgkNBSqNKEKlW-v2xpl4lImD7RRm1weBlysvgjNTKmDBypLP56NzfU-SPGZ0zijLX6zna3Q4z2iWzZkUrCjuJDMmZZGWOZN3kxktS55WQrCD5IH3a0pZwbm8nxzwnNOC02qW_FzqELQjwZLQaqJrE6x7Sa6vvi860xuEjmALDjBCxgeD_jkZ2q03trOrndxoCKPT8R76mtgxoN1oT8B7iwaCrslXE1rSbgftEIbeADE9GSAY3Qe_FwHHoCfEftMbgyTaDcZBjLIlDZgu-pN61FPKxen5yZuUVWmamt6bVRs9Gmc3u_gfP9nz4w9n6Q4iPoz19vrqx8PkXgOd149uzsPk89vjs8X7dHn67mTxepmi4CKkTEDdQAW6roq8FCDyTDQN8gwbBjVKzAEbiaKomixqUFLJyrwqLmqkuWA5P0xe7X2H8WKja4zzOejU4MwG3FZZMOpvpTetWtlLVRVCFHQyeHZj4OyXUfugNsaj7jrotR29yuLOOJOsEBF9-g-6tqPr43iRkjyXgkoeqWxPobPeO93chmFUTR1SazV1SE0dUvsOxUdP_hzj9snv0kTgaA_o-JmXRjvlMS4TY3mcxqBqa_7n_wtRHd9U</recordid><startdate>20230201</startdate><enddate>20230201</enddate><creator>Bhattacharya, Dipasri</creator><creator>Bhakta, Pradipta</creator><creator>O'Brien, Brian</creator><creator>Karim, Habib Md Reazaul</creator><creator>Esquinas, Antonio M.</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ASE</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FPQ</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K6X</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20230201</creationdate><title>Letter to the editor: “Clinical characteristics, physiological features, and outcomes associated with hypercapnia in patients with acute hypoxemic respiratory failure due to COVID-19---insights from the PRoVENT-COVID study”</title><author>Bhattacharya, Dipasri ; 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[...]ventilatory ratio, defined as [minute ventilation (ml/min) × partial pressure of arterial CO2 tension (mm Hg)]/(predicted body weight × 100 × 37.5), is a simple bedside index of assessing the efficiency of mechanical ventilation [6]. [...]hypoxemia, quantified by the ratio of partial pressure arterial oxygen tension and fraction of inspired oxygen concentration (PaO2/FiO2), does not necessarily assess the alveolar ventilation and physiological dead space which reflect the overall efficacy of the lungs to eliminate the CO2 load.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>36307309</pmid><doi>10.1016/j.jcrc.2022.154177</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of critical care, 2023-02, Vol.73, p.154177-154177, Article 154177 |
| issn | 0883-9441 1557-8615 |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier); ProQuest Central UK/Ireland |
| subjects | ARDS, lung protective ventilation Carbon dioxide Coronaviruses COVID-19 Editing Humans Hypercapnia Mortality Outcomes Physiology Respiration, Artificial - adverse effects Respiratory Distress Syndrome - etiology Respiratory Distress Syndrome - therapy Respiratory Insufficiency - etiology Respiratory Insufficiency - therapy Ventilation Ventilators Writing |
| title | Letter to the editor: “Clinical characteristics, physiological features, and outcomes associated with hypercapnia in patients with acute hypoxemic respiratory failure due to COVID-19---insights from the PRoVENT-COVID study” |
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