The complexity of ventral CA1 and its multiple functionalities

The hippocampus is one of the most widely investigated brain regions with its massive contributions to multiple behaviours. Especially, the hippocampus is subdivided into the dorsal and ventral parts playing distinct roles. In this review, we will focus on the ventral hippocampus, especially the ven...

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Veröffentlicht in:Genes, brain and behavior brain and behavior, 2022-09, Vol.21 (7), p.e12826-n/a
Hauptverfasser: Hong, Ilgang, Kaang, Bong‐Kiun
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Kaang, Bong‐Kiun
description The hippocampus is one of the most widely investigated brain regions with its massive contributions to multiple behaviours. Especially, the hippocampus is subdivided into the dorsal and ventral parts playing distinct roles. In this review, we will focus on the ventral hippocampus, especially the ventral CA1 (vCA1), whose role is being actively discovered. vCA1 is well known to be associated with emotion‐like behaviour, in both positive (reward) and negative (aversive) stimuli. How can this small region in volume mediate such variety of responses? This question will be answered with technologies up to date that have allowed us to study in‐depth the specific neural circuit and to map the complex connectivity.
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subjects Anxiety
autism
Behavior
Brain research
Fear - physiology
fear conditioning
Hippocampus
Hippocampus - physiology
learning and memory
Memory
Neural networks
Neurosciences
Reinforcement
Review
reward
Roles
ventral CA1
title The complexity of ventral CA1 and its multiple functionalities
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