Scientific journey to the first FDA-approved drug for eosinophilic esophagitis

When eosinophilia was first associated with esophagitis, it was thought to reflect gastroesophageal reflux disease, especially given the efficacy of reflux medications to abate esophageal eosinophilia in many individuals. Subsequent studies demonstrated disease remittance with amino acid–based formu...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2022-12, Vol.150 (6), p.1325-1332
1. Verfasser:	Rothenberg, Marc E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cytokines Discovery dupilumab eosinophils esophagitis FDA Humans IL-13 IL-4 IL-5 Mice Pharmaceutical Preparations United States United States Food and Drug Administration
Online-Zugang:	Volltext
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