Initial Treatment of High-Altitude Pulmonary Edema: Comparison of Oxygen and Auto-PEEP
Improvement of oxygenation is the aim in the therapy of high-altitude pulmonary edema (HAPE). However, descent is often difficult and hyperbaric chambers, as well as bottled oxygen, are often not available. We compare Auto-PEEP (AP-Pat), a special kind of pursed lips breathing, against the applicati...
Gespeichert in:
| Veröffentlicht in: | International journal of environmental research and public health 2022-12, Vol.19 (23), p.16185 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 23 |
| container_start_page | 16185 |
| container_title | International journal of environmental research and public health |
| container_volume | 19 |
| creator | Tannheimer, Markus Lechner, Raimund |
| description | Improvement of oxygenation is the aim in the therapy of high-altitude pulmonary edema (HAPE). However, descent is often difficult and hyperbaric chambers, as well as bottled oxygen, are often not available. We compare Auto-PEEP (AP-Pat), a special kind of pursed lips breathing, against the application of bottled oxygen (O
-Pat) in two patients suffering from HAPE.
We compare the effect of these two different therapies on oxygen saturation measured by pulse oximetry (SpO
) over time.
In both patients SpO
increased significantly from 65-70% to 95%. Above 80% this increase was slower in AP-Pat compared with O
-Pat. Therapy started immediately in AP-Pat but was delayed in O
-Pat because of organizational and logistic reasons.
The well-established therapies of HAPE are always the option of choice, if available, and should be started as soon as possible. The advantage of Auto-PEEP is its all-time availability. It improves SpO
nearly as well as 3 L/min oxygen and furthermore has a positive effect on oxygenation lasting for approximately 120 min after stopping. Auto-PEEP treatment does not appear inferior to oxygen treatment, at least in this cross-case comparison. Its immediate application after diagnosis probably plays an important role here. |
| doi_str_mv | 10.3390/ijerph192316185 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9737163</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2753308574</sourcerecordid><originalsourceid>FETCH-LOGICAL-c421t-ec21ce0b08f00897dcb09460e2d1697d6cb1aea7865046addce7ec8bc6e7f2653</originalsourceid><addsrcrecordid>eNpdkctLxDAQxoMovs_epODFSzVp2iT1ICzL-gDBPajXkKbT3Sxtsiap6H9vxAfqaWaY33x8w4fQEcFnlNb43KzAr5ekLihhRFQbaJcwhvOSYbL5q99BeyGsMKaiZPU22qGsrEVR8V30dGtNNKrPHjyoOICNmeuyG7NY5pM-mji2kM3HfnBW-bds1sKgLrKpG9bKm-DsB3z_-rYAmynbZpMxunw-m80P0Fan-gCHX3UfPV7NHqY3-d399e10cpfrsiAxB10QDbjBosNY1LzVDa6TYShawtLIdEMUKC5YhUum2lYDBy0azYB3BavoPrr81F2PzQBpbaNXvVx7MyS_0ikj_26sWcqFe5E1p5wwmgROvwS8ex4hRDmYoKHvlQU3BlnwilIsKl4m9OQfunKjt-m9RJWiKhkvRKLOPyntXQgeuh8zBMuPzOS_zNLF8e8ffvjvkOg7QJKT9w</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2748546728</pqid></control><display><type>article</type><title>Initial Treatment of High-Altitude Pulmonary Edema: Comparison of Oxygen and Auto-PEEP</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central Open Access</source><source>MDPI - Multidisciplinary Digital Publishing Institute</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Tannheimer, Markus ; Lechner, Raimund</creator><creatorcontrib>Tannheimer, Markus ; Lechner, Raimund</creatorcontrib><description>Improvement of oxygenation is the aim in the therapy of high-altitude pulmonary edema (HAPE). However, descent is often difficult and hyperbaric chambers, as well as bottled oxygen, are often not available. We compare Auto-PEEP (AP-Pat), a special kind of pursed lips breathing, against the application of bottled oxygen (O
-Pat) in two patients suffering from HAPE.
We compare the effect of these two different therapies on oxygen saturation measured by pulse oximetry (SpO
) over time.
In both patients SpO
increased significantly from 65-70% to 95%. Above 80% this increase was slower in AP-Pat compared with O
-Pat. Therapy started immediately in AP-Pat but was delayed in O
-Pat because of organizational and logistic reasons.
The well-established therapies of HAPE are always the option of choice, if available, and should be started as soon as possible. The advantage of Auto-PEEP is its all-time availability. It improves SpO
nearly as well as 3 L/min oxygen and furthermore has a positive effect on oxygenation lasting for approximately 120 min after stopping. Auto-PEEP treatment does not appear inferior to oxygen treatment, at least in this cross-case comparison. Its immediate application after diagnosis probably plays an important role here.</description><identifier>ISSN: 1660-4601</identifier><identifier>ISSN: 1661-7827</identifier><identifier>EISSN: 1660-4601</identifier><identifier>DOI: 10.3390/ijerph192316185</identifier><identifier>PMID: 36498257</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Altitude ; Altitude Sickness - complications ; Altitude Sickness - therapy ; Availability ; Dyspnea ; Edema ; High altitude ; High-altitude environments ; Humans ; Hyperbaric chambers ; Nonsteroidal anti-inflammatory drugs ; Oximetry ; Oximetry - adverse effects ; Oxygen - therapeutic use ; Oxygen content ; Oxygenation ; Pulmonary Edema - etiology ; Pulmonary Edema - therapy ; Radio communications</subject><ispartof>International journal of environmental research and public health, 2022-12, Vol.19 (23), p.16185</ispartof><rights>2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2022 by the authors. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c421t-ec21ce0b08f00897dcb09460e2d1697d6cb1aea7865046addce7ec8bc6e7f2653</citedby><cites>FETCH-LOGICAL-c421t-ec21ce0b08f00897dcb09460e2d1697d6cb1aea7865046addce7ec8bc6e7f2653</cites><orcidid>0000-0001-7830-6470</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737163/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737163/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36498257$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tannheimer, Markus</creatorcontrib><creatorcontrib>Lechner, Raimund</creatorcontrib><title>Initial Treatment of High-Altitude Pulmonary Edema: Comparison of Oxygen and Auto-PEEP</title><title>International journal of environmental research and public health</title><addtitle>Int J Environ Res Public Health</addtitle><description>Improvement of oxygenation is the aim in the therapy of high-altitude pulmonary edema (HAPE). However, descent is often difficult and hyperbaric chambers, as well as bottled oxygen, are often not available. We compare Auto-PEEP (AP-Pat), a special kind of pursed lips breathing, against the application of bottled oxygen (O
-Pat) in two patients suffering from HAPE.
We compare the effect of these two different therapies on oxygen saturation measured by pulse oximetry (SpO
) over time.
In both patients SpO
increased significantly from 65-70% to 95%. Above 80% this increase was slower in AP-Pat compared with O
-Pat. Therapy started immediately in AP-Pat but was delayed in O
-Pat because of organizational and logistic reasons.
The well-established therapies of HAPE are always the option of choice, if available, and should be started as soon as possible. The advantage of Auto-PEEP is its all-time availability. It improves SpO
nearly as well as 3 L/min oxygen and furthermore has a positive effect on oxygenation lasting for approximately 120 min after stopping. Auto-PEEP treatment does not appear inferior to oxygen treatment, at least in this cross-case comparison. Its immediate application after diagnosis probably plays an important role here.</description><subject>Altitude</subject><subject>Altitude Sickness - complications</subject><subject>Altitude Sickness - therapy</subject><subject>Availability</subject><subject>Dyspnea</subject><subject>Edema</subject><subject>High altitude</subject><subject>High-altitude environments</subject><subject>Humans</subject><subject>Hyperbaric chambers</subject><subject>Nonsteroidal anti-inflammatory drugs</subject><subject>Oximetry</subject><subject>Oximetry - adverse effects</subject><subject>Oxygen - therapeutic use</subject><subject>Oxygen content</subject><subject>Oxygenation</subject><subject>Pulmonary Edema - etiology</subject><subject>Pulmonary Edema - therapy</subject><subject>Radio communications</subject><issn>1660-4601</issn><issn>1661-7827</issn><issn>1660-4601</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkctLxDAQxoMovs_epODFSzVp2iT1ICzL-gDBPajXkKbT3Sxtsiap6H9vxAfqaWaY33x8w4fQEcFnlNb43KzAr5ekLihhRFQbaJcwhvOSYbL5q99BeyGsMKaiZPU22qGsrEVR8V30dGtNNKrPHjyoOICNmeuyG7NY5pM-mji2kM3HfnBW-bds1sKgLrKpG9bKm-DsB3z_-rYAmynbZpMxunw-m80P0Fan-gCHX3UfPV7NHqY3-d399e10cpfrsiAxB10QDbjBosNY1LzVDa6TYShawtLIdEMUKC5YhUum2lYDBy0azYB3BavoPrr81F2PzQBpbaNXvVx7MyS_0ikj_26sWcqFe5E1p5wwmgROvwS8ex4hRDmYoKHvlQU3BlnwilIsKl4m9OQfunKjt-m9RJWiKhkvRKLOPyntXQgeuh8zBMuPzOS_zNLF8e8ffvjvkOg7QJKT9w</recordid><startdate>20221203</startdate><enddate>20221203</enddate><creator>Tannheimer, Markus</creator><creator>Lechner, Raimund</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-7830-6470</orcidid></search><sort><creationdate>20221203</creationdate><title>Initial Treatment of High-Altitude Pulmonary Edema: Comparison of Oxygen and Auto-PEEP</title><author>Tannheimer, Markus ; Lechner, Raimund</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c421t-ec21ce0b08f00897dcb09460e2d1697d6cb1aea7865046addce7ec8bc6e7f2653</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Altitude</topic><topic>Altitude Sickness - complications</topic><topic>Altitude Sickness - therapy</topic><topic>Availability</topic><topic>Dyspnea</topic><topic>Edema</topic><topic>High altitude</topic><topic>High-altitude environments</topic><topic>Humans</topic><topic>Hyperbaric chambers</topic><topic>Nonsteroidal anti-inflammatory drugs</topic><topic>Oximetry</topic><topic>Oximetry - adverse effects</topic><topic>Oxygen - therapeutic use</topic><topic>Oxygen content</topic><topic>Oxygenation</topic><topic>Pulmonary Edema - etiology</topic><topic>Pulmonary Edema - therapy</topic><topic>Radio communications</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tannheimer, Markus</creatorcontrib><creatorcontrib>Lechner, Raimund</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal of environmental research and public health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tannheimer, Markus</au><au>Lechner, Raimund</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Initial Treatment of High-Altitude Pulmonary Edema: Comparison of Oxygen and Auto-PEEP</atitle><jtitle>International journal of environmental research and public health</jtitle><addtitle>Int J Environ Res Public Health</addtitle><date>2022-12-03</date><risdate>2022</risdate><volume>19</volume><issue>23</issue><spage>16185</spage><pages>16185-</pages><issn>1660-4601</issn><issn>1661-7827</issn><eissn>1660-4601</eissn><abstract>Improvement of oxygenation is the aim in the therapy of high-altitude pulmonary edema (HAPE). However, descent is often difficult and hyperbaric chambers, as well as bottled oxygen, are often not available. We compare Auto-PEEP (AP-Pat), a special kind of pursed lips breathing, against the application of bottled oxygen (O
-Pat) in two patients suffering from HAPE.
We compare the effect of these two different therapies on oxygen saturation measured by pulse oximetry (SpO
) over time.
In both patients SpO
increased significantly from 65-70% to 95%. Above 80% this increase was slower in AP-Pat compared with O
-Pat. Therapy started immediately in AP-Pat but was delayed in O
-Pat because of organizational and logistic reasons.
The well-established therapies of HAPE are always the option of choice, if available, and should be started as soon as possible. The advantage of Auto-PEEP is its all-time availability. It improves SpO
nearly as well as 3 L/min oxygen and furthermore has a positive effect on oxygenation lasting for approximately 120 min after stopping. Auto-PEEP treatment does not appear inferior to oxygen treatment, at least in this cross-case comparison. Its immediate application after diagnosis probably plays an important role here.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>36498257</pmid><doi>10.3390/ijerph192316185</doi><orcidid>https://orcid.org/0000-0001-7830-6470</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1660-4601 |
| ispartof | International journal of environmental research and public health, 2022-12, Vol.19 (23), p.16185 |
| issn | 1660-4601 1661-7827 1660-4601 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9737163 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Altitude Altitude Sickness - complications Altitude Sickness - therapy Availability Dyspnea Edema High altitude High-altitude environments Humans Hyperbaric chambers Nonsteroidal anti-inflammatory drugs Oximetry Oximetry - adverse effects Oxygen - therapeutic use Oxygen content Oxygenation Pulmonary Edema - etiology Pulmonary Edema - therapy Radio communications |
| title | Initial Treatment of High-Altitude Pulmonary Edema: Comparison of Oxygen and Auto-PEEP |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T00%3A45%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Initial%20Treatment%20of%20High-Altitude%20Pulmonary%20Edema:%20Comparison%20of%20Oxygen%20and%20Auto-PEEP&rft.jtitle=International%20journal%20of%20environmental%20research%20and%20public%20health&rft.au=Tannheimer,%20Markus&rft.date=2022-12-03&rft.volume=19&rft.issue=23&rft.spage=16185&rft.pages=16185-&rft.issn=1660-4601&rft.eissn=1660-4601&rft_id=info:doi/10.3390/ijerph192316185&rft_dat=%3Cproquest_pubme%3E2753308574%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2748546728&rft_id=info:pmid/36498257&rfr_iscdi=true |