Hepatoblastoma Cancer Stem Cells Express PD-L1, Reveal Plasticity and Can Emerge upon Chemotherapy

The biology of cancer stem cells (CSCs) of pediatric cancers, such as hepatoblastoma, is sparsely explored. This is mainly due to the very immature nature of these tumors, which complicates the distinction of CSCs from the other tumor cells. Previously, we identified a CSC population in hepatoblasto...

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Veröffentlicht in:	Cancers 2022-11, Vol.14 (23), p.5825
Hauptverfasser:	Lee-Theilen, Mieun, Fadini, Delaine D, Hadhoud, Julia R, van Dongen, Fleur, Kroll, Gabriela, Rolle, Udo, Fiegel, Henning C
Format:	Artikel
Sprache:	eng
Schlagworte:	5-aza-2'-deoxycytidine Antibodies Cancer Cancer cells Cancer therapies Care and treatment CD34 antigen Cell surface Chemotherapy Cisplatin Cloning Flow cytometry Health aspects Keratin Laboratories Liver cancer Metastasis Methods PD-L1 protein Pediatrics Plasticity Pluripotency R&D Research & development Stem cells Tumor cells Tumorigenesis Tumors Vimentin
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