Aruncus dioicus var. kamtschaticus Extract Ameliorates Psoriasis-like Skin Inflammation via Akt/mTOR and JAK2/STAT3 Signaling Pathways in a Murine Model

Goat's beard ( var. ) is a traditional medicinal plant, widely used in Chinese and Korean traditional medicine because of its anti-inflammatory, anti-oxidant, antimicrobial, and anti-cancer activity. However, its effect on skin inflammatory diseases like psoriasis is unknown. The aim of this st...

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Veröffentlicht in:	Nutrients 2022-12, Vol.14 (23), p.5094
Hauptverfasser:	Dorjsembe, Banzragch, Joo, Haneul, Nho, Chuwon, Ham, Jungyeob, Kim, Jin-Chul
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein Animal models Animals Antibodies Antigens Antiinfectives and antibacterials Antitumor activity Antiviral drugs Aruncus dioicus Cell Proliferation Chemokines Dendritic cells Dermatitis Disease Models, Animal Drug dosages Erythema Gene expression Herbal medicine Imiquimod Immune system Inflammation Inflammatory diseases Janus kinase Janus Kinase 2 Keratinocytes Kinases Laboratories Ligands Mammals Medicinal plants Mice Mice, Inbred BALB C Oxidants Oxidizing agents Plant Extracts - pharmacology Plant Extracts - therapeutic use Proteins Proto-Oncogene Proteins c-akt Psoriasis Psoriasis - drug therapy Rapamycin Rosaceae Signal Transduction Skin Skin diseases Stat3 protein TOR protein TOR Serine-Threonine Kinases Transcription factors Transducers Tumor necrosis factor-TNF
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