Phase angle (PhA) in overweight and obesity: evidence of applicability from diagnosis to weight changes in obesity treatment

Phase angle (PhA) is a recently proposed marker of nutritional status in many clinical conditions. Its use in patients with obesity presents different critical concerns due to the higher variability of the two measured parameters (resistance, R, and reactance, Xc) that contribute to the determinatio...

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Veröffentlicht in:Reviews in endocrine & metabolic disorders 2023-06, Vol.24 (3), p.451-464
Hauptverfasser: Cancello, Raffaella, Brunani, Amelia, Brenna, Ettore, Soranna, Davide, Bertoli, Simona, Zambon, Antonella, Lukaski, Henry C., Capodaglio, Paolo
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container_issue 3
container_start_page 451
container_title Reviews in endocrine & metabolic disorders
container_volume 24
creator Cancello, Raffaella
Brunani, Amelia
Brenna, Ettore
Soranna, Davide
Bertoli, Simona
Zambon, Antonella
Lukaski, Henry C.
Capodaglio, Paolo
description Phase angle (PhA) is a recently proposed marker of nutritional status in many clinical conditions. Its use in patients with obesity presents different critical concerns due to the higher variability of the two measured parameters (resistance, R, and reactance, Xc) that contribute to the determination of PhA. Controversial is the relation between PhA and BMI that might vary with graded levels of obesity due to the variation in fat and free fat mass. Obesity is frequently associated with metabolic, hepatic, cardiovascular and kidney diseases that introduce variations in PhA values, in relation to multimorbidity and severity degree of these diseases. It is reported that the improvement of clinical condition is associated with a positive change in PhA. Also, the treatment of obesity with weight loss might confirm this effect, but with different responses in relation to the type and duration of the intervention applied. In fact, the effect appears not only related to the percentage of weight loss but also the possible loss of free fat mass and the nutritional, metabolic and structural modifications that might follow each therapeutic approach to decrease body weight. We can conclude that the PhA could be used as marker of health status in patients with obesity supporting an appropriate weight loss intervention to monitor efficacy and fat free mass preservation.
doi_str_mv 10.1007/s11154-022-09774-1
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subjects Analysis
Body Composition - physiology
Body fat
Body weight
Body weight loss
Diabetes
Diagnosis
Drug therapy
Endocrinology
Humans
Internal Medicine
Kidney diseases
Liver diseases
Medicine
Medicine & Public Health
Metabolism
Nutritional Status
Obesity
Obesity - therapy
Overweight
Overweight - therapy
Patients
Type 2 diabetes
Weight control
Weight Loss
title Phase angle (PhA) in overweight and obesity: evidence of applicability from diagnosis to weight changes in obesity treatment
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