Single-cell CRISPR immune screens reveal immunological roles of tumor intrinsic factors

Genetic screens are widely exploited to develop novel therapeutic approaches for cancer treatment. With recent advances in single-cell technology, single-cell CRISPR screen (scCRISPR) platforms provide opportunities for target validation and mechanistic studies in a high-throughput manner. Here, we...

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Veröffentlicht in:	NAR cancer 2022-12, Vol.4 (4), p.zcac038
Hauptverfasser:	Hou, Jiakai, Liang, Shaoheng, Xu, Chunyu, Wei, Yanjun, Wang, Yunfei, Tan, Yukun, Sahni, Nidhi, McGrail, Daniel J, Bernatchez, Chantale, Davies, Michael, Li, Yumei, Chen, Rui, Yi, S Stephen, Chen, Yiwen, Yee, Cassian, Chen, Ken, Peng, Weiyi
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer gene Regulation, Chromatin and Epigenetics Editor's Choice
Online-Zugang:	Volltext
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