Molecular docking analysis of metformin analogues with GSK-3β

Molecular docking analysis of metformin analogues with GSK-3β

We report the molecular docking analysis of four analogues of metformin [1-Carbamimidoyl-1,2-dimethylguanidine hydrochloride, Metformin hydrochloride, N1,N1-Dimethyl-N5-methylbiguanide hydrochloride, and N1,N1,N5,N5-Tetrakis (methyl-biguanide hydrochloride] with GSK3.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Bioinformation 2022-03, Vol.18 (3), p.269-272
Hauptverfasser: Rajagopal, Ponnu Lakshmi, Umapathy, Vidhya Rekha, P, Sandhya, Jh, Fathima, Govindan, Ramajayam, Palanisamy, Chella Perumal, Veeraraghavan, Vishnu Priya, Jayaraman, Selvaraj
Format: Artikel
Sprache:eng
Schlagworte:
Metformin
Molecular docking
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 272
container_issue 3
container_start_page 269
container_title Bioinformation
container_volume 18
creator Rajagopal, Ponnu Lakshmi
Umapathy, Vidhya Rekha
P, Sandhya
Jh, Fathima
Govindan, Ramajayam
Palanisamy, Chella Perumal
Veeraraghavan, Vishnu Priya
Jayaraman, Selvaraj
description We report the molecular docking analysis of four analogues of metformin [1-Carbamimidoyl-1,2-dimethylguanidine hydrochloride, Metformin hydrochloride, N1,N1-Dimethyl-N5-methylbiguanide hydrochloride, and N1,N1,N5,N5-Tetrakis (methyl-biguanide hydrochloride] with GSK3.
doi_str_mv 10.6026/97320630018269
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9722410</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2754857360</sourcerecordid><originalsourceid>FETCH-LOGICAL-c348t-2c045cd6aa31aa363255f0596bcf6ed9bd640bec2fe72e18c1254817ed626d203</originalsourceid><addsrcrecordid>eNpdkU9PwyAAxYnRuDm9ejRNvHjp5H_byxKz6DTOeFDPhFK6MdsyodXsa_lB_Ey2bi7TA4E8fjx4PABOERxyiPllEhEMOYEQxZgne6APWyXspP2ddQ8ceb-AkKIoYoegRzhDMSK0D0YPttCqKaQLMqteTTULZCWLlTc-sHlQ6jq3rjTVj2pnjfbBh6nnweTpPiRfn8fgIJeF1yebeQBebq6fx7fh9HFyN76ahorQuA6xgpSpjEtJUDs4wYzlkCU8VTnXWZJmnMJUK5zrCGsUK4QZjVGkM455hiEZgNHad9mkpc6UrmonC7F0ppRuJaw04u9OZeZiZt9FEmFMUWdwsTFw9q1NUYvSeKWLQlbaNl7gqL2QRYR36Pk_dGEb18Zvqe7fKGdJRw3XlHLWe6fz7WMQFF014m817YGz3Qhb_LcL8g3REYjn</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2651846590</pqid></control><display><type>article</type><title>Molecular docking analysis of metformin analogues with GSK-3β</title><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>PubMed Central Open Access</source><creator>Rajagopal, Ponnu Lakshmi ; Umapathy, Vidhya Rekha ; P, Sandhya ; Jh, Fathima ; Govindan, Ramajayam ; Palanisamy, Chella Perumal ; Veeraraghavan, Vishnu Priya ; Jayaraman, Selvaraj</creator><creatorcontrib>Rajagopal, Ponnu Lakshmi ; Umapathy, Vidhya Rekha ; P, Sandhya ; Jh, Fathima ; Govindan, Ramajayam ; Palanisamy, Chella Perumal ; Veeraraghavan, Vishnu Priya ; Jayaraman, Selvaraj ; Central Research Laboratory, Meenakshi Academy of Higher Education and Research (Deemed to be University), Chennai, India</creatorcontrib><description>We report the molecular docking analysis of four analogues of metformin [1-Carbamimidoyl-1,2-dimethylguanidine hydrochloride, Metformin hydrochloride, N1,N1-Dimethyl-N5-methylbiguanide hydrochloride, and N1,N1,N5,N5-Tetrakis (methyl-biguanide hydrochloride] with GSK3.</description><identifier>ISSN: 0973-2063</identifier><identifier>ISSN: 0973-8894</identifier><identifier>EISSN: 0973-2063</identifier><identifier>DOI: 10.6026/97320630018269</identifier><identifier>PMID: 36518134</identifier><language>eng</language><publisher>Singapore: Biomedical Informatics</publisher><subject>Metformin ; Molecular docking</subject><ispartof>Bioinformation, 2022-03, Vol.18 (3), p.269-272</ispartof><rights>2022 Biomedical Informatics.</rights><rights>Copyright Biomedical Informatics Mar 2022</rights><rights>2022 Biomedical Informatics 2022</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c348t-2c045cd6aa31aa363255f0596bcf6ed9bd640bec2fe72e18c1254817ed626d203</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722410/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722410/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36518134$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rajagopal, Ponnu Lakshmi</creatorcontrib><creatorcontrib>Umapathy, Vidhya Rekha</creatorcontrib><creatorcontrib>P, Sandhya</creatorcontrib><creatorcontrib>Jh, Fathima</creatorcontrib><creatorcontrib>Govindan, Ramajayam</creatorcontrib><creatorcontrib>Palanisamy, Chella Perumal</creatorcontrib><creatorcontrib>Veeraraghavan, Vishnu Priya</creatorcontrib><creatorcontrib>Jayaraman, Selvaraj</creatorcontrib><creatorcontrib>Central Research Laboratory, Meenakshi Academy of Higher Education and Research (Deemed to be University), Chennai, India</creatorcontrib><title>Molecular docking analysis of metformin analogues with GSK-3β</title><title>Bioinformation</title><addtitle>Bioinformation</addtitle><description>We report the molecular docking analysis of four analogues of metformin [1-Carbamimidoyl-1,2-dimethylguanidine hydrochloride, Metformin hydrochloride, N1,N1-Dimethyl-N5-methylbiguanide hydrochloride, and N1,N1,N5,N5-Tetrakis (methyl-biguanide hydrochloride] with GSK3.</description><subject>Metformin</subject><subject>Molecular docking</subject><issn>0973-2063</issn><issn>0973-8894</issn><issn>0973-2063</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNpdkU9PwyAAxYnRuDm9ejRNvHjp5H_byxKz6DTOeFDPhFK6MdsyodXsa_lB_Ey2bi7TA4E8fjx4PABOERxyiPllEhEMOYEQxZgne6APWyXspP2ddQ8ceb-AkKIoYoegRzhDMSK0D0YPttCqKaQLMqteTTULZCWLlTc-sHlQ6jq3rjTVj2pnjfbBh6nnweTpPiRfn8fgIJeF1yebeQBebq6fx7fh9HFyN76ahorQuA6xgpSpjEtJUDs4wYzlkCU8VTnXWZJmnMJUK5zrCGsUK4QZjVGkM455hiEZgNHad9mkpc6UrmonC7F0ppRuJaw04u9OZeZiZt9FEmFMUWdwsTFw9q1NUYvSeKWLQlbaNl7gqL2QRYR36Pk_dGEb18Zvqe7fKGdJRw3XlHLWe6fz7WMQFF014m817YGz3Qhb_LcL8g3REYjn</recordid><startdate>20220331</startdate><enddate>20220331</enddate><creator>Rajagopal, Ponnu Lakshmi</creator><creator>Umapathy, Vidhya Rekha</creator><creator>P, Sandhya</creator><creator>Jh, Fathima</creator><creator>Govindan, Ramajayam</creator><creator>Palanisamy, Chella Perumal</creator><creator>Veeraraghavan, Vishnu Priya</creator><creator>Jayaraman, Selvaraj</creator><general>Biomedical Informatics</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7QO</scope><scope>7T5</scope><scope>7TK</scope><scope>7TM</scope><scope>7TO</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20220331</creationdate><title>Molecular docking analysis of metformin analogues with GSK-3β</title><author>Rajagopal, Ponnu Lakshmi ; Umapathy, Vidhya Rekha ; P, Sandhya ; Jh, Fathima ; Govindan, Ramajayam ; Palanisamy, Chella Perumal ; Veeraraghavan, Vishnu Priya ; Jayaraman, Selvaraj</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c348t-2c045cd6aa31aa363255f0596bcf6ed9bd640bec2fe72e18c1254817ed626d203</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Metformin</topic><topic>Molecular docking</topic><toplevel>online_resources</toplevel><creatorcontrib>Rajagopal, Ponnu Lakshmi</creatorcontrib><creatorcontrib>Umapathy, Vidhya Rekha</creatorcontrib><creatorcontrib>P, Sandhya</creatorcontrib><creatorcontrib>Jh, Fathima</creatorcontrib><creatorcontrib>Govindan, Ramajayam</creatorcontrib><creatorcontrib>Palanisamy, Chella Perumal</creatorcontrib><creatorcontrib>Veeraraghavan, Vishnu Priya</creatorcontrib><creatorcontrib>Jayaraman, Selvaraj</creatorcontrib><creatorcontrib>Central Research Laboratory, Meenakshi Academy of Higher Education and Research (Deemed to be University), Chennai, India</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Bioinformation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rajagopal, Ponnu Lakshmi</au><au>Umapathy, Vidhya Rekha</au><au>P, Sandhya</au><au>Jh, Fathima</au><au>Govindan, Ramajayam</au><au>Palanisamy, Chella Perumal</au><au>Veeraraghavan, Vishnu Priya</au><au>Jayaraman, Selvaraj</au><aucorp>Central Research Laboratory, Meenakshi Academy of Higher Education and Research (Deemed to be University), Chennai, India</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Molecular docking analysis of metformin analogues with GSK-3β</atitle><jtitle>Bioinformation</jtitle><addtitle>Bioinformation</addtitle><date>2022-03-31</date><risdate>2022</risdate><volume>18</volume><issue>3</issue><spage>269</spage><epage>272</epage><pages>269-272</pages><issn>0973-2063</issn><issn>0973-8894</issn><eissn>0973-2063</eissn><abstract>We report the molecular docking analysis of four analogues of metformin [1-Carbamimidoyl-1,2-dimethylguanidine hydrochloride, Metformin hydrochloride, N1,N1-Dimethyl-N5-methylbiguanide hydrochloride, and N1,N1,N5,N5-Tetrakis (methyl-biguanide hydrochloride] with GSK3.</abstract><cop>Singapore</cop><pub>Biomedical Informatics</pub><pmid>36518134</pmid><doi>10.6026/97320630018269</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0973-2063
ispartof Bioinformation, 2022-03, Vol.18 (3), p.269-272
issn 0973-2063
0973-8894
0973-2063
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9722410
source EZB-FREE-00999 freely available EZB journals; PubMed Central; PubMed Central Open Access
subjects Metformin
Molecular docking
title Molecular docking analysis of metformin analogues with GSK-3β
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T13%3A03%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Molecular%20docking%20analysis%20of%20metformin%20analogues%20with%20GSK-3%CE%B2&rft.jtitle=Bioinformation&rft.au=Rajagopal,%20Ponnu%20Lakshmi&rft.aucorp=Central%20Research%20Laboratory,%20Meenakshi%20Academy%20of%20Higher%20Education%20and%20Research%20(Deemed%20to%20be%20University),%20Chennai,%20India&rft.date=2022-03-31&rft.volume=18&rft.issue=3&rft.spage=269&rft.epage=272&rft.pages=269-272&rft.issn=0973-2063&rft.eissn=0973-2063&rft_id=info:doi/10.6026/97320630018269&rft_dat=%3Cproquest_pubme%3E2754857360%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2651846590&rft_id=info:pmid/36518134&rfr_iscdi=true