Specificity and Breadth of the Neutralizing Antibody Response to a Live-Attenuated Tetravalent Dengue Vaccine

An effective dengue vaccine should ideally induce broadly neutralizing antibody (nAb) responses against all 4 dengue virus (DENV) serotypes. We characterized the specificity and breadth of the nAb response to TAK-003, a live-attenuated tetravalent dengue vaccine, in serum samples from phase 2 and 3...

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Veröffentlicht in:	The Journal of infectious diseases 2022-11, Vol.226 (11), p.1959-1963
Hauptverfasser:	DeMaso, Christina R, Karwal, Lovkesh, Zahralban-Steele, Melissa, Dominguez, David, Springer, Zhang-Li, Kaiser, Maima, Palani, Sunil, Rindfleisch, Tim, Bohning, Kelly, Hather, Greg, Das, Subash, Sharma, Mayuri, Dean, Hansi J
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Neutralizing Antibodies, Viral Brief Report Dengue Dengue Vaccines Dengue Virus Humans Vaccines, Attenuated Vaccines, Combined
Online-Zugang:	Volltext
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