Silk Sericin: A Promising Sustainable Biomaterial for Biomedical and Pharmaceutical Applications
Silk is a natural composite fiber composed mainly of hydrophobic fibroin and hydrophilic sericin, produced by the silkworm In the textile industry, the cocoons of are processed into silk fabric, where the sericin is substantially removed and usually discarded in wastewater. This wastewater pollutes...
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| Veröffentlicht in: | Polymers 2022-11, Vol.14 (22), p.4931 |
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| creator | Silva, Andreia S Costa, Elisabete C Reis, Sara Spencer, Carina Calhelha, Ricardo C Miguel, Sónia P Ribeiro, Maximiano P Barros, Lillian Vaz, Josiana A Coutinho, Paula |
| description | Silk is a natural composite fiber composed mainly of hydrophobic fibroin and hydrophilic sericin, produced by the silkworm
In the textile industry, the cocoons of
are processed into silk fabric, where the sericin is substantially removed and usually discarded in wastewater. This wastewater pollutes the environment and water sources. However, sericin has been recognized as a potential biomaterial due to its biocompatibility, immunocompatibility, biodegradability, anti-inflammatory, antibacterial, antioxidant and photoprotective properties. Moreover, sericin can produce hydrogels, films, sponges, foams, dressings, particles, fibers, etc., for various biomedical and pharmaceutical applications (e.g., tissue engineering, wound healing, drug delivery, cosmetics). Given the severe environmental pollution caused by the disposal of sericin and its beneficial properties, there has been growing interest in upcycling this biomaterial, which could have a strong and positive economic, social and environmental impact. |
| doi_str_mv | 10.3390/polym14224931 |
| format | Article |
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In the textile industry, the cocoons of
are processed into silk fabric, where the sericin is substantially removed and usually discarded in wastewater. This wastewater pollutes the environment and water sources. However, sericin has been recognized as a potential biomaterial due to its biocompatibility, immunocompatibility, biodegradability, anti-inflammatory, antibacterial, antioxidant and photoprotective properties. Moreover, sericin can produce hydrogels, films, sponges, foams, dressings, particles, fibers, etc., for various biomedical and pharmaceutical applications (e.g., tissue engineering, wound healing, drug delivery, cosmetics). Given the severe environmental pollution caused by the disposal of sericin and its beneficial properties, there has been growing interest in upcycling this biomaterial, which could have a strong and positive economic, social and environmental impact.</description><identifier>ISSN: 2073-4360</identifier><identifier>EISSN: 2073-4360</identifier><identifier>DOI: 10.3390/polym14224931</identifier><identifier>PMID: 36433058</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Amino acids ; Biocompatibility ; Biodegradability ; Biological products ; Biomedical engineering ; Biomedical materials ; Chemical oxygen demand ; Cosmetics ; Drug delivery systems ; Drugs ; Environmental engineering ; Environmental impact ; Enzymes ; Hydrogels ; Hydrogen bonds ; Impact analysis ; Methods ; Molecular weight ; Peptides ; Pharmaceuticals ; Proteins ; Review ; Silk ; Silkworms ; Sodium ; Technology application ; Textile industry ; Tissue engineering ; Vehicles ; Wastewater ; Wound healing</subject><ispartof>Polymers, 2022-11, Vol.14 (22), p.4931</ispartof><rights>COPYRIGHT 2022 MDPI AG</rights><rights>2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2022 by the authors. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c482t-8a2e5510b4a7f0019e17fb4c70e22a34c42720035b58f0b3b16b2cc85b88108f3</citedby><cites>FETCH-LOGICAL-c482t-8a2e5510b4a7f0019e17fb4c70e22a34c42720035b58f0b3b16b2cc85b88108f3</cites><orcidid>0000-0002-9050-5189 ; 0000-0001-7274-0399 ; 0000-0001-6832-3082 ; 0000-0002-6989-1169 ; 0000-0002-6801-4578 ; 0000-0001-6357-8115 ; 0000-0003-3440-4831</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699483/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699483/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36433058$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Silva, Andreia S</creatorcontrib><creatorcontrib>Costa, Elisabete C</creatorcontrib><creatorcontrib>Reis, Sara</creatorcontrib><creatorcontrib>Spencer, Carina</creatorcontrib><creatorcontrib>Calhelha, Ricardo C</creatorcontrib><creatorcontrib>Miguel, Sónia P</creatorcontrib><creatorcontrib>Ribeiro, Maximiano P</creatorcontrib><creatorcontrib>Barros, Lillian</creatorcontrib><creatorcontrib>Vaz, Josiana A</creatorcontrib><creatorcontrib>Coutinho, Paula</creatorcontrib><title>Silk Sericin: A Promising Sustainable Biomaterial for Biomedical and Pharmaceutical Applications</title><title>Polymers</title><addtitle>Polymers (Basel)</addtitle><description>Silk is a natural composite fiber composed mainly of hydrophobic fibroin and hydrophilic sericin, produced by the silkworm
In the textile industry, the cocoons of
are processed into silk fabric, where the sericin is substantially removed and usually discarded in wastewater. This wastewater pollutes the environment and water sources. However, sericin has been recognized as a potential biomaterial due to its biocompatibility, immunocompatibility, biodegradability, anti-inflammatory, antibacterial, antioxidant and photoprotective properties. Moreover, sericin can produce hydrogels, films, sponges, foams, dressings, particles, fibers, etc., for various biomedical and pharmaceutical applications (e.g., tissue engineering, wound healing, drug delivery, cosmetics). Given the severe environmental pollution caused by the disposal of sericin and its beneficial properties, there has been growing interest in upcycling this biomaterial, which could have a strong and positive economic, social and environmental impact.</description><subject>Amino acids</subject><subject>Biocompatibility</subject><subject>Biodegradability</subject><subject>Biological products</subject><subject>Biomedical engineering</subject><subject>Biomedical materials</subject><subject>Chemical oxygen demand</subject><subject>Cosmetics</subject><subject>Drug delivery systems</subject><subject>Drugs</subject><subject>Environmental engineering</subject><subject>Environmental impact</subject><subject>Enzymes</subject><subject>Hydrogels</subject><subject>Hydrogen bonds</subject><subject>Impact analysis</subject><subject>Methods</subject><subject>Molecular weight</subject><subject>Peptides</subject><subject>Pharmaceuticals</subject><subject>Proteins</subject><subject>Review</subject><subject>Silk</subject><subject>Silkworms</subject><subject>Sodium</subject><subject>Technology application</subject><subject>Textile industry</subject><subject>Tissue engineering</subject><subject>Vehicles</subject><subject>Wastewater</subject><subject>Wound healing</subject><issn>2073-4360</issn><issn>2073-4360</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNptUU1LxDAQDaKoqEevUvBczVeb1IOwLn6BoLB6jkk2WaNtUpNW8N8bv10wc8jM5M3jZR4AuwgeENLAwz60rx2iGNOGoBWwiSEjJSU1XP2Tb4CdlB5hPrSqa8TWwQapKSGw4pvgfubap2JmotPOHxWT4iaGziXnF8VsTIN0XqrWFCcudHLIKNkWNsSP2sydzqX08-LmQcZOajMOH61J37c5GVzwaRusWdkms_N1b4G7s9Pb6UV5dX1-OZ1clZpyPJRcYlNVCCoqmYUQNQYxq6hm0GAsCdUUMwwhqVTFLVREoVphrXmlOEeQW7IFjj95-1Fladr4IcpW9NF1Mr6KIJ1YfvHuQSzCi2jqpqGcZIL9L4IYnkeTBvEYxuizZoEZaWhFKGK_qIVsjXDehkym88a0mDBaU_q-54w6-AeVY246p4M31uX-0kD5OaBjSCka-yMcQfFutViyOuP3_v72B_1tLHkDlNakGA</recordid><startdate>20221115</startdate><enddate>20221115</enddate><creator>Silva, Andreia S</creator><creator>Costa, Elisabete C</creator><creator>Reis, Sara</creator><creator>Spencer, Carina</creator><creator>Calhelha, Ricardo C</creator><creator>Miguel, Sónia P</creator><creator>Ribeiro, Maximiano P</creator><creator>Barros, Lillian</creator><creator>Vaz, Josiana A</creator><creator>Coutinho, Paula</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>HCIFZ</scope><scope>JG9</scope><scope>KB.</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-9050-5189</orcidid><orcidid>https://orcid.org/0000-0001-7274-0399</orcidid><orcidid>https://orcid.org/0000-0001-6832-3082</orcidid><orcidid>https://orcid.org/0000-0002-6989-1169</orcidid><orcidid>https://orcid.org/0000-0002-6801-4578</orcidid><orcidid>https://orcid.org/0000-0001-6357-8115</orcidid><orcidid>https://orcid.org/0000-0003-3440-4831</orcidid></search><sort><creationdate>20221115</creationdate><title>Silk Sericin: A Promising Sustainable Biomaterial for Biomedical and Pharmaceutical Applications</title><author>Silva, Andreia S ; Costa, Elisabete C ; Reis, Sara ; Spencer, Carina ; Calhelha, Ricardo C ; Miguel, Sónia P ; Ribeiro, Maximiano P ; Barros, Lillian ; Vaz, Josiana A ; Coutinho, Paula</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c482t-8a2e5510b4a7f0019e17fb4c70e22a34c42720035b58f0b3b16b2cc85b88108f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Amino acids</topic><topic>Biocompatibility</topic><topic>Biodegradability</topic><topic>Biological products</topic><topic>Biomedical engineering</topic><topic>Biomedical materials</topic><topic>Chemical oxygen demand</topic><topic>Cosmetics</topic><topic>Drug delivery systems</topic><topic>Drugs</topic><topic>Environmental engineering</topic><topic>Environmental impact</topic><topic>Enzymes</topic><topic>Hydrogels</topic><topic>Hydrogen bonds</topic><topic>Impact analysis</topic><topic>Methods</topic><topic>Molecular weight</topic><topic>Peptides</topic><topic>Pharmaceuticals</topic><topic>Proteins</topic><topic>Review</topic><topic>Silk</topic><topic>Silkworms</topic><topic>Sodium</topic><topic>Technology application</topic><topic>Textile industry</topic><topic>Tissue engineering</topic><topic>Vehicles</topic><topic>Wastewater</topic><topic>Wound healing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Silva, Andreia S</creatorcontrib><creatorcontrib>Costa, Elisabete C</creatorcontrib><creatorcontrib>Reis, Sara</creatorcontrib><creatorcontrib>Spencer, Carina</creatorcontrib><creatorcontrib>Calhelha, Ricardo C</creatorcontrib><creatorcontrib>Miguel, Sónia P</creatorcontrib><creatorcontrib>Ribeiro, Maximiano P</creatorcontrib><creatorcontrib>Barros, Lillian</creatorcontrib><creatorcontrib>Vaz, Josiana A</creatorcontrib><creatorcontrib>Coutinho, Paula</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>SciTech Premium Collection</collection><collection>Materials Research Database</collection><collection>Materials Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Polymers</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Silva, Andreia S</au><au>Costa, Elisabete C</au><au>Reis, Sara</au><au>Spencer, Carina</au><au>Calhelha, Ricardo C</au><au>Miguel, Sónia P</au><au>Ribeiro, Maximiano P</au><au>Barros, Lillian</au><au>Vaz, Josiana A</au><au>Coutinho, Paula</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Silk Sericin: A Promising Sustainable Biomaterial for Biomedical and Pharmaceutical Applications</atitle><jtitle>Polymers</jtitle><addtitle>Polymers (Basel)</addtitle><date>2022-11-15</date><risdate>2022</risdate><volume>14</volume><issue>22</issue><spage>4931</spage><pages>4931-</pages><issn>2073-4360</issn><eissn>2073-4360</eissn><abstract>Silk is a natural composite fiber composed mainly of hydrophobic fibroin and hydrophilic sericin, produced by the silkworm
In the textile industry, the cocoons of
are processed into silk fabric, where the sericin is substantially removed and usually discarded in wastewater. This wastewater pollutes the environment and water sources. However, sericin has been recognized as a potential biomaterial due to its biocompatibility, immunocompatibility, biodegradability, anti-inflammatory, antibacterial, antioxidant and photoprotective properties. Moreover, sericin can produce hydrogels, films, sponges, foams, dressings, particles, fibers, etc., for various biomedical and pharmaceutical applications (e.g., tissue engineering, wound healing, drug delivery, cosmetics). Given the severe environmental pollution caused by the disposal of sericin and its beneficial properties, there has been growing interest in upcycling this biomaterial, which could have a strong and positive economic, social and environmental impact.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>36433058</pmid><doi>10.3390/polym14224931</doi><orcidid>https://orcid.org/0000-0002-9050-5189</orcidid><orcidid>https://orcid.org/0000-0001-7274-0399</orcidid><orcidid>https://orcid.org/0000-0001-6832-3082</orcidid><orcidid>https://orcid.org/0000-0002-6989-1169</orcidid><orcidid>https://orcid.org/0000-0002-6801-4578</orcidid><orcidid>https://orcid.org/0000-0001-6357-8115</orcidid><orcidid>https://orcid.org/0000-0003-3440-4831</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Amino acids Biocompatibility Biodegradability Biological products Biomedical engineering Biomedical materials Chemical oxygen demand Cosmetics Drug delivery systems Drugs Environmental engineering Environmental impact Enzymes Hydrogels Hydrogen bonds Impact analysis Methods Molecular weight Peptides Pharmaceuticals Proteins Review Silk Silkworms Sodium Technology application Textile industry Tissue engineering Vehicles Wastewater Wound healing |
| title | Silk Sericin: A Promising Sustainable Biomaterial for Biomedical and Pharmaceutical Applications |
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