Engineering Modified mRNA-Based Vaccine against Dengue Virus Using Computational and Reverse Vaccinology Approaches

Dengue virus belonging to the family and its four serotypes are responsible for dengue infections, which extend over 60 countries in tropical and subtropical areas of the world including Pakistan. During the ongoing dengue outbreak in Pakistan (2022), over 30,000 cases have been reported, and over 7...

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Veröffentlicht in:	International journal of molecular sciences 2022-11, Vol.23 (22), p.13911
Hauptverfasser:	Mukhtar, Mamuna, Wajeeha, Amtul Wadood, Zaidi, Najam Us Sahar Sadaf, Bibi, Naseeha
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergenicity Antigenicity Commercialization Computer applications Cytotoxicity Dengue - prevention & control Dengue fever Dengue Vaccines - genetics Dengue Virus - genetics Encephalitis Energy Epidemics Epitopes Genomes Histocompatibility antigen HLA Humans Immune response Immunological memory Infections Infectious diseases Lymphocytes Lymphocytes B Lymphocytes T Molecular docking Molecular Docking Simulation mRNA mRNA Vaccines Nucleotides Optimization Proteins RNA, Messenger - genetics Serotypes Servers Tropical diseases Vaccines Vaccinology Viruses West Nile virus
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