Association of Systemic Trimethyllysine With Heart Failure With Preserved Ejection Fraction and Cardiovascular Events

Abstract Context Carnitine has been associated with cardiac energy metabolism and heart failure, but the association between its precursors—trimethyllysine (TML) and γ-butyrobetaine (GBB)—and heart failure with preserved ejection fraction (HFpEF) remains unclear. Objective To evaluate the relationsh...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2022-12, Vol.107 (12), p.e4360-e4370
Hauptverfasser:	Wei, Haoran, Zhao, Mingming, Wu, Junfang, Li, Chenze, Huang, Man, Gao, Jianing, Zhang, Qi, Ji, Liang, Wang, Yan, Zhao, Chunxia, Dong, Erdan, Zheng, Lemin, Wang, Dao Wen
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Cardiovascular diseases Carnitine Clinical Congestive heart failure Coronary heart disease Ejection fraction Energy metabolism Ethylenediaminetetraacetic acid Glomerular filtration rate Heart failure Liquid chromatography Low density lipoproteins Mass spectrometry Mass spectroscopy Medical research Medicine, Experimental Metabolites Natriuretic peptides Plasma Population studies Renal function Risk factors Triglycerides Trimethylamine Trimethylamine-N-oxide
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