Impact of Vitiligo on Life Quality of Patients: Assessment of Currently Available Tools
How different tools for evaluating health-related quality of life (QoL) reflect the burden of vitiligo has rarely been compared. In this study, we aim to evaluate the impact of vitiligo on QoL using currently available tools. A single-center, cross-sectional study of vitiligo patients was performed....
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| Veröffentlicht in: | International journal of environmental research and public health 2022-11, Vol.19 (22), p.14943 |
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| creator | Yang, Ting-Ting Lee, Chien-Hung Lan, Cheng-Che E |
| description | How different tools for evaluating health-related quality of life (QoL) reflect the burden of vitiligo has rarely been compared. In this study, we aim to evaluate the impact of vitiligo on QoL using currently available tools.
A single-center, cross-sectional study of vitiligo patients was performed. QoL was evaluated using the dermatology life quality index (DLQI), short form-36 (SF-36), and willingness to pay (WTP). As the original DLQI cutoff score (>10) indicating aginificantly impated QoL was found to underestimate QoL, receiver operating characteristic (ROC) curve was use to determine a new cutoff point discriminating vitiligo patients with positive mental stress (SF-36 mental health ≤ 52).
Of the 143 patients enrolled, 24.5% were identified having significant mental stress by SF-36 mental health domain score ≤ 52 while there were only 13.3% patients with significantly hampered QoL indicated by DLQI >10. Using ROC analysis, DLQI ≥ 7 was found to be a more appropriate DLQI cutoff value for identifying mental stress in vitiligo patients. Additionally, the median WTP for treating vitiligo was comparable to other inflammatory skin diseases.
There exist discrepancies in the outcomes identifying significant disease burden of vitiligo using DLQI and SF-36, making the current DLQI cutoff score (>10) for identifying significantly affected QoL inappropriate for these patients. |
| doi_str_mv | 10.3390/ijerph192214943 |
| format | Article |
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A single-center, cross-sectional study of vitiligo patients was performed. QoL was evaluated using the dermatology life quality index (DLQI), short form-36 (SF-36), and willingness to pay (WTP). As the original DLQI cutoff score (>10) indicating aginificantly impated QoL was found to underestimate QoL, receiver operating characteristic (ROC) curve was use to determine a new cutoff point discriminating vitiligo patients with positive mental stress (SF-36 mental health ≤ 52).
Of the 143 patients enrolled, 24.5% were identified having significant mental stress by SF-36 mental health domain score ≤ 52 while there were only 13.3% patients with significantly hampered QoL indicated by DLQI >10. Using ROC analysis, DLQI ≥ 7 was found to be a more appropriate DLQI cutoff value for identifying mental stress in vitiligo patients. Additionally, the median WTP for treating vitiligo was comparable to other inflammatory skin diseases.
There exist discrepancies in the outcomes identifying significant disease burden of vitiligo using DLQI and SF-36, making the current DLQI cutoff score (>10) for identifying significantly affected QoL inappropriate for these patients.</description><identifier>ISSN: 1660-4601</identifier><identifier>ISSN: 1661-7827</identifier><identifier>EISSN: 1660-4601</identifier><identifier>DOI: 10.3390/ijerph192214943</identifier><identifier>PMID: 36429664</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Cost of Illness ; Cross-Sectional Studies ; Demographics ; Dermatology ; Evaluation ; Health surveys ; Humans ; Mental health ; Patients ; Psychological stress ; Quality assessment ; Quality of life ; Quality of Life - psychology ; Questionnaires ; Skin diseases ; Stress ; Surveys and Questionnaires ; Vitiligo ; Willingness to pay</subject><ispartof>International journal of environmental research and public health, 2022-11, Vol.19 (22), p.14943</ispartof><rights>2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2022 by the authors. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c351t-a20228f40ac029b7ed2272cc394679de369124abe9f9595d4c8628c4db34d3753</citedby><cites>FETCH-LOGICAL-c351t-a20228f40ac029b7ed2272cc394679de369124abe9f9595d4c8628c4db34d3753</cites><orcidid>0000-0001-9515-5336 ; 0000-0002-0988-264X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690871/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690871/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36429664$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yang, Ting-Ting</creatorcontrib><creatorcontrib>Lee, Chien-Hung</creatorcontrib><creatorcontrib>Lan, Cheng-Che E</creatorcontrib><title>Impact of Vitiligo on Life Quality of Patients: Assessment of Currently Available Tools</title><title>International journal of environmental research and public health</title><addtitle>Int J Environ Res Public Health</addtitle><description>How different tools for evaluating health-related quality of life (QoL) reflect the burden of vitiligo has rarely been compared. In this study, we aim to evaluate the impact of vitiligo on QoL using currently available tools.
A single-center, cross-sectional study of vitiligo patients was performed. QoL was evaluated using the dermatology life quality index (DLQI), short form-36 (SF-36), and willingness to pay (WTP). As the original DLQI cutoff score (>10) indicating aginificantly impated QoL was found to underestimate QoL, receiver operating characteristic (ROC) curve was use to determine a new cutoff point discriminating vitiligo patients with positive mental stress (SF-36 mental health ≤ 52).
Of the 143 patients enrolled, 24.5% were identified having significant mental stress by SF-36 mental health domain score ≤ 52 while there were only 13.3% patients with significantly hampered QoL indicated by DLQI >10. Using ROC analysis, DLQI ≥ 7 was found to be a more appropriate DLQI cutoff value for identifying mental stress in vitiligo patients. Additionally, the median WTP for treating vitiligo was comparable to other inflammatory skin diseases.
There exist discrepancies in the outcomes identifying significant disease burden of vitiligo using DLQI and SF-36, making the current DLQI cutoff score (>10) for identifying significantly affected QoL inappropriate for these patients.</description><subject>Cost of Illness</subject><subject>Cross-Sectional Studies</subject><subject>Demographics</subject><subject>Dermatology</subject><subject>Evaluation</subject><subject>Health surveys</subject><subject>Humans</subject><subject>Mental health</subject><subject>Patients</subject><subject>Psychological stress</subject><subject>Quality assessment</subject><subject>Quality of life</subject><subject>Quality of Life - psychology</subject><subject>Questionnaires</subject><subject>Skin diseases</subject><subject>Stress</subject><subject>Surveys and Questionnaires</subject><subject>Vitiligo</subject><subject>Willingness to pay</subject><issn>1660-4601</issn><issn>1661-7827</issn><issn>1660-4601</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdUV1LwzAUDaK4OX32TQo-1-WraeODMIYfg4EKUx9DmqZbRtfUpB3s35uxOaZP9-Oce-7hXgCuEbwjhMOhWWrXLBDHGFFOyQnoI8ZgTBlEp0d5D1x4v4SQZJTxc9AjjGLOGO2Dr8mqkaqNbBl9mtZUZm4jW0dTU-rovZOVaTdb7E22Rtetv49G3mvvV6HY9sedcyGtNtFoLU0l80pHM2srfwnOSll5fbWPA_Dx9Dgbv8TT1-fJeDSNFUlQG0sMMc5KCqWCmOepLjBOsVKEU5byQhPGEaYy17zkCU8KqjKGM0WLnNCCpAkZgIedbtPlK12oYMbJSjTOrKTbCCuN-IvUZiHmdi044zBLURC43Qs4-91p34ql7VwdPAucBhs4YwwH1nDHUs5673R52ICg2H5C_PtEmLg5Nnbg_56e_ABuT4X0</recordid><startdate>20221113</startdate><enddate>20221113</enddate><creator>Yang, Ting-Ting</creator><creator>Lee, Chien-Hung</creator><creator>Lan, Cheng-Che E</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-9515-5336</orcidid><orcidid>https://orcid.org/0000-0002-0988-264X</orcidid></search><sort><creationdate>20221113</creationdate><title>Impact of Vitiligo on Life Quality of Patients: Assessment of Currently Available Tools</title><author>Yang, Ting-Ting ; Lee, Chien-Hung ; Lan, Cheng-Che E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c351t-a20228f40ac029b7ed2272cc394679de369124abe9f9595d4c8628c4db34d3753</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Cost of Illness</topic><topic>Cross-Sectional Studies</topic><topic>Demographics</topic><topic>Dermatology</topic><topic>Evaluation</topic><topic>Health surveys</topic><topic>Humans</topic><topic>Mental health</topic><topic>Patients</topic><topic>Psychological stress</topic><topic>Quality assessment</topic><topic>Quality of life</topic><topic>Quality of Life - psychology</topic><topic>Questionnaires</topic><topic>Skin diseases</topic><topic>Stress</topic><topic>Surveys and Questionnaires</topic><topic>Vitiligo</topic><topic>Willingness to pay</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yang, Ting-Ting</creatorcontrib><creatorcontrib>Lee, Chien-Hung</creatorcontrib><creatorcontrib>Lan, Cheng-Che E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal of environmental research and public health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yang, Ting-Ting</au><au>Lee, Chien-Hung</au><au>Lan, Cheng-Che E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of Vitiligo on Life Quality of Patients: Assessment of Currently Available Tools</atitle><jtitle>International journal of environmental research and public health</jtitle><addtitle>Int J Environ Res Public Health</addtitle><date>2022-11-13</date><risdate>2022</risdate><volume>19</volume><issue>22</issue><spage>14943</spage><pages>14943-</pages><issn>1660-4601</issn><issn>1661-7827</issn><eissn>1660-4601</eissn><abstract>How different tools for evaluating health-related quality of life (QoL) reflect the burden of vitiligo has rarely been compared. In this study, we aim to evaluate the impact of vitiligo on QoL using currently available tools.
A single-center, cross-sectional study of vitiligo patients was performed. QoL was evaluated using the dermatology life quality index (DLQI), short form-36 (SF-36), and willingness to pay (WTP). As the original DLQI cutoff score (>10) indicating aginificantly impated QoL was found to underestimate QoL, receiver operating characteristic (ROC) curve was use to determine a new cutoff point discriminating vitiligo patients with positive mental stress (SF-36 mental health ≤ 52).
Of the 143 patients enrolled, 24.5% were identified having significant mental stress by SF-36 mental health domain score ≤ 52 while there were only 13.3% patients with significantly hampered QoL indicated by DLQI >10. Using ROC analysis, DLQI ≥ 7 was found to be a more appropriate DLQI cutoff value for identifying mental stress in vitiligo patients. Additionally, the median WTP for treating vitiligo was comparable to other inflammatory skin diseases.
There exist discrepancies in the outcomes identifying significant disease burden of vitiligo using DLQI and SF-36, making the current DLQI cutoff score (>10) for identifying significantly affected QoL inappropriate for these patients.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>36429664</pmid><doi>10.3390/ijerph192214943</doi><orcidid>https://orcid.org/0000-0001-9515-5336</orcidid><orcidid>https://orcid.org/0000-0002-0988-264X</orcidid><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Cost of Illness Cross-Sectional Studies Demographics Dermatology Evaluation Health surveys Humans Mental health Patients Psychological stress Quality assessment Quality of life Quality of Life - psychology Questionnaires Skin diseases Stress Surveys and Questionnaires Vitiligo Willingness to pay |
| title | Impact of Vitiligo on Life Quality of Patients: Assessment of Currently Available Tools |
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