Regression of Lung Cancer in Mice by Intranasal Administration of SARS-CoV-2 Spike S1

This study underlines the importance of SARS-CoV-2 spike S1 in prompting death in cultured non-small cell lung cancer (NSCLC) cells and in vivo in lung tumors in mice. Interestingly, we found that recombinant spike S1 treatment at very low doses led to death of human A549 NSCLC cells. On the other h...

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Veröffentlicht in:	Cancers 2022-11, Vol.14 (22), p.5648
Hauptverfasser:	Sheinin, Monica, Jeong, Brian, Paidi, Ramesh K, Pahan, Kalipada
Format:	Artikel
Sprache:	eng
Schlagworte:	4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone ACE2 Angiogenesis Angiotensin Angiotensin converting enzyme Angiotensin-converting enzyme 2 Antibodies Apoptosis Care and treatment Cell death COVID-19 Dehydrogenases Flow cytometry Health aspects Intoxication Intranasal administration Lung cancer Non-small cell lung carcinoma Patient outcomes Peptidyl-dipeptidase A Proteins Severe acute respiratory syndrome coronavirus 2 Small cell lung carcinoma Tumors Viral proteins
Online-Zugang:	Volltext
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