Highly multiplexed spatial profiling with CODEX: bioinformatic analysis and application in human disease

Multiplexed imaging, which enables spatial localization of proteins and RNA to cells within tissues, complements existing multi-omic technologies and has deepened our understanding of health and disease. CODEX, a multiplexed single-cell imaging technology, utilizes a microfluidics system that incorp...

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Veröffentlicht in:	Seminars in immunopathology 2023-01, Vol.45 (1), p.145-157
Hauptverfasser:	Kuswanto, Wilson, Nolan, Garry, Lu, Guolan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Autoimmune Diseases Autoimmunity Bioinformatics Biomedical and Life Sciences Biomedicine Computational Biology Humans Immunology Infections Internal Medicine Localization Medicine Microfluidics Microscopy Multiomics Neoplasms Pathology Proteins Review Segmentation Single-Cell Analysis Spatial analysis Spatial discrimination
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