Associations Between Cognitive Function and Levels of Glutamatergic Metabolites and Gamma-Aminobutyric Acid in Antipsychotic-Naïve Patients With Schizophrenia or Psychosis

Abnormal glutamate and GABA (gamma-aminobutyric acid) levels have been found in the early phase of schizophrenia and may underlie cognitive deficits. However, the association between cognitive function and levels of glutamatergic metabolites and GABA has not been investigated in a large group of ant...

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Veröffentlicht in:	Biological psychiatry (1969) 2021-02, Vol.89 (3), p.278-287
Hauptverfasser:	Bojesen, Kirsten Borup, Broberg, Brian Villumsen, Fagerlund, Birgitte, Jessen, Kasper, Thomas, Marie Bjerregaard, Sigvard, Anne, Tangmose, Karen, Nielsen, Mette Ødegaard, Andersen, Gitte Saltoft, Larsson, Henrik Bo Wiberg, Edden, Richard A.E., Rostrup, Egill, Glenthøj, Birte Yding
Format:	Artikel
Sprache:	eng
Schlagworte:	Anterior cingulate cortex Antipsychotic Agents Antipsychotic-naïve schizophrenia Cognition GABA gamma-Aminobutyric Acid Glutamate Glutamic Acid Glutamine Gyrus Cinguli Humans Magnetic resonance spectroscopy Psychotic Disorders Schizophrenia
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