Evaluation of Magnetic Resonance Findings of Circumventricular Organs in Idiopathic Intracranial Hypertension Patients
Background: Idiopathic intracranial hypertension (IIH) is the increased pressure with normal cerebrospinal fluid (CSF) composition, not due to a secondary cause. However, the need for lumbar puncture, an invasive method in diagnosis, leads to research on noninvasive diagnostic methods. This study ai...
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description | Background: Idiopathic intracranial hypertension (IIH) is the increased pressure with normal cerebrospinal fluid (CSF) composition, not due to a secondary cause. However, the need for lumbar puncture, an invasive method in diagnosis, leads to research on noninvasive diagnostic methods. This study aims to examine the role of the size of the pituitary gland and the previously unevaluated pineal gland in radiological diagnosis in patients with IIH.Materials and methods: The study retrospectively included 57 patients aged 18-80 years, who were followed up in our clinic with the diagnosis of IIH, and 52 control patients without central nervous system disease and cranial MR pathology. CSF pressure measurement values, CSF biochemistry, and cytology examinations were recorded as a result of lumbar puncture performed in the lateral decubitus position of all patients. In addition, the pineal gland and pituitary dimensions were measured by a neuroradiologist on cranial MR imaging of both groups.Results: Pituitary gland height, anteroposterior (AP), and transverse dimensions were found to be significantly lower in the IIH patient group than in the control group (p0.05).Conclusion: Our findings suggest that measurement of pituitary and pineal gland sizes in neuroimaging may be a guide as a noninvasive method in diagnosing and treating IIH. |
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However, the need for lumbar puncture, an invasive method in diagnosis, leads to research on noninvasive diagnostic methods. This study aims to examine the role of the size of the pituitary gland and the previously unevaluated pineal gland in radiological diagnosis in patients with IIH.Materials and methods: The study retrospectively included 57 patients aged 18-80 years, who were followed up in our clinic with the diagnosis of IIH, and 52 control patients without central nervous system disease and cranial MR pathology. CSF pressure measurement values, CSF biochemistry, and cytology examinations were recorded as a result of lumbar puncture performed in the lateral decubitus position of all patients. In addition, the pineal gland and pituitary dimensions were measured by a neuroradiologist on cranial MR imaging of both groups.Results: Pituitary gland height, anteroposterior (AP), and transverse dimensions were found to be significantly lower in the IIH patient group than in the control group (p<0.05). There were a significant reduction in pineal gland AP and height measurements in the IIH patient group compared to the control group. Still, we found no significant difference between the two groups in transverse measurements (p>0.05).Conclusion: Our findings suggest that measurement of pituitary and pineal gland sizes in neuroimaging may be a guide as a noninvasive method in diagnosing and treating IIH.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.31795</identifier><language>eng</language><publisher>Palo Alto: Cureus Inc</publisher><subject>Brain research ; Cerebrospinal fluid ; Disease ; Endocrine system ; Headaches ; Hypertension ; Intracranial pressure ; Magnetic resonance imaging ; Melatonin ; Neurology ; Neurosurgery ; Optic nerve ; Patients ; Pituitary gland ; Radiology ; Tinnitus</subject><ispartof>Curēus (Palo Alto, CA), 2022-11, Vol.14 (11), p.e31795-e31795</ispartof><rights>Copyright © 2022, Mraja et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2022, Mraja et al. 2022 Mraja et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c276t-73e0d250c6d3d6985df4e31e5aee404ded64870be6dcad2d6beae4930fb859443</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681503/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681503/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids></links><search><creatorcontrib>Mraja, Sule Nur</creatorcontrib><creatorcontrib>Akdogan, Ozlem</creatorcontrib><creatorcontrib>Mraja, Hamisi M</creatorcontrib><creatorcontrib>Emre, Ufuk</creatorcontrib><creatorcontrib>Karagöz, Yeşim</creatorcontrib><title>Evaluation of Magnetic Resonance Findings of Circumventricular Organs in Idiopathic Intracranial Hypertension Patients</title><title>Curēus (Palo Alto, CA)</title><description>Background: Idiopathic intracranial hypertension (IIH) is the increased pressure with normal cerebrospinal fluid (CSF) composition, not due to a secondary cause. However, the need for lumbar puncture, an invasive method in diagnosis, leads to research on noninvasive diagnostic methods. This study aims to examine the role of the size of the pituitary gland and the previously unevaluated pineal gland in radiological diagnosis in patients with IIH.Materials and methods: The study retrospectively included 57 patients aged 18-80 years, who were followed up in our clinic with the diagnosis of IIH, and 52 control patients without central nervous system disease and cranial MR pathology. CSF pressure measurement values, CSF biochemistry, and cytology examinations were recorded as a result of lumbar puncture performed in the lateral decubitus position of all patients. In addition, the pineal gland and pituitary dimensions were measured by a neuroradiologist on cranial MR imaging of both groups.Results: Pituitary gland height, anteroposterior (AP), and transverse dimensions were found to be significantly lower in the IIH patient group than in the control group (p<0.05). There were a significant reduction in pineal gland AP and height measurements in the IIH patient group compared to the control group. Still, we found no significant difference between the two groups in transverse measurements (p>0.05).Conclusion: Our findings suggest that measurement of pituitary and pineal gland sizes in neuroimaging may be a guide as a noninvasive method in diagnosing and treating IIH.</description><subject>Brain research</subject><subject>Cerebrospinal fluid</subject><subject>Disease</subject><subject>Endocrine system</subject><subject>Headaches</subject><subject>Hypertension</subject><subject>Intracranial pressure</subject><subject>Magnetic resonance imaging</subject><subject>Melatonin</subject><subject>Neurology</subject><subject>Neurosurgery</subject><subject>Optic nerve</subject><subject>Patients</subject><subject>Pituitary gland</subject><subject>Radiology</subject><subject>Tinnitus</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkU9rGzEQxZfQQI2TWz_AQi491In-raS9FIqJG0NKSkjOYizNOgpryZVWBn_77NahtD3NwPvNmxleVX2i5Fqppr2xJWHJ15yqtjmrZoxKvdBUiw9_9R-ry5xfCSGUKEYUmVWH2wP0BQYfQx27-gdsAw7e1o-YY4BgsV754HzY5kle-mTL7oBhSN6WHlL9kLYQcu1DvXY-7mF4GYfXow42QfDQ13fHPaYBQ55W_Bw3jdP5ojrvoM94-V7n1fPq9ml5t7h_-L5efrtfWKbksFAciWMNsdJxJ1vduE4gp9gAoiDCoZNCK7JB6Sw45uQGAUXLSbfRTSsEn1dfT777stmhs9Pl0Jt98jtIRxPBm3-V4F_MNh5MKzVtCB8NPr8bpPirYB7MzmeLfQ8BY8mGKUEayrjWI3r1H_oaSwrjexPFWiZpq0bqy4myKeacsPtzDCVmCtKcgjS_g-RvD-6WJA</recordid><startdate>20221122</startdate><enddate>20221122</enddate><creator>Mraja, Sule Nur</creator><creator>Akdogan, Ozlem</creator><creator>Mraja, Hamisi M</creator><creator>Emre, Ufuk</creator><creator>Karagöz, Yeşim</creator><general>Cureus Inc</general><general>Cureus</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20221122</creationdate><title>Evaluation of Magnetic Resonance Findings of Circumventricular Organs in Idiopathic Intracranial Hypertension Patients</title><author>Mraja, Sule Nur ; Akdogan, Ozlem ; Mraja, Hamisi M ; Emre, Ufuk ; Karagöz, Yeşim</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c276t-73e0d250c6d3d6985df4e31e5aee404ded64870be6dcad2d6beae4930fb859443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Brain research</topic><topic>Cerebrospinal fluid</topic><topic>Disease</topic><topic>Endocrine system</topic><topic>Headaches</topic><topic>Hypertension</topic><topic>Intracranial pressure</topic><topic>Magnetic resonance imaging</topic><topic>Melatonin</topic><topic>Neurology</topic><topic>Neurosurgery</topic><topic>Optic nerve</topic><topic>Patients</topic><topic>Pituitary gland</topic><topic>Radiology</topic><topic>Tinnitus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mraja, Sule Nur</creatorcontrib><creatorcontrib>Akdogan, Ozlem</creatorcontrib><creatorcontrib>Mraja, Hamisi M</creatorcontrib><creatorcontrib>Emre, Ufuk</creatorcontrib><creatorcontrib>Karagöz, Yeşim</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mraja, Sule Nur</au><au>Akdogan, Ozlem</au><au>Mraja, Hamisi M</au><au>Emre, Ufuk</au><au>Karagöz, Yeşim</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of Magnetic Resonance Findings of Circumventricular Organs in Idiopathic Intracranial Hypertension Patients</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><date>2022-11-22</date><risdate>2022</risdate><volume>14</volume><issue>11</issue><spage>e31795</spage><epage>e31795</epage><pages>e31795-e31795</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Background: Idiopathic intracranial hypertension (IIH) is the increased pressure with normal cerebrospinal fluid (CSF) composition, not due to a secondary cause. However, the need for lumbar puncture, an invasive method in diagnosis, leads to research on noninvasive diagnostic methods. This study aims to examine the role of the size of the pituitary gland and the previously unevaluated pineal gland in radiological diagnosis in patients with IIH.Materials and methods: The study retrospectively included 57 patients aged 18-80 years, who were followed up in our clinic with the diagnosis of IIH, and 52 control patients without central nervous system disease and cranial MR pathology. CSF pressure measurement values, CSF biochemistry, and cytology examinations were recorded as a result of lumbar puncture performed in the lateral decubitus position of all patients. In addition, the pineal gland and pituitary dimensions were measured by a neuroradiologist on cranial MR imaging of both groups.Results: Pituitary gland height, anteroposterior (AP), and transverse dimensions were found to be significantly lower in the IIH patient group than in the control group (p<0.05). There were a significant reduction in pineal gland AP and height measurements in the IIH patient group compared to the control group. Still, we found no significant difference between the two groups in transverse measurements (p>0.05).Conclusion: Our findings suggest that measurement of pituitary and pineal gland sizes in neuroimaging may be a guide as a noninvasive method in diagnosing and treating IIH.</abstract><cop>Palo Alto</cop><pub>Cureus Inc</pub><doi>10.7759/cureus.31795</doi><oa>free_for_read</oa></addata></record> |
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subjects | Brain research Cerebrospinal fluid Disease Endocrine system Headaches Hypertension Intracranial pressure Magnetic resonance imaging Melatonin Neurology Neurosurgery Optic nerve Patients Pituitary gland Radiology Tinnitus |
title | Evaluation of Magnetic Resonance Findings of Circumventricular Organs in Idiopathic Intracranial Hypertension Patients |
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