Spatial intra-tumor heterogeneity is associated with survival of lung adenocarcinoma patients

Intra-tumor heterogeneity (ITH) of human tumors is important for tumor progression, treatment response, and drug resistance. However, the spatial distribution of ITH remains incompletely understood. Here, we present spatial analysis of ITH in lung adenocarcinomas from 147 patients using multi-region...

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Veröffentlicht in:Cell genomics 2022-08, Vol.2 (8), p.100165, Article 100165
Hauptverfasser: Wu, Hua-Jun, Temko, Daniel, Maliga, Zoltan, Moreira, Andre L, Sei, Emi, Minussi, Darlan Conterno, Dean, Jamie, Lee, Charlotte, Xu, Qiong, Hochart, Guillaume, Jacobson, Connor A, Yapp, Clarence, Schapiro, Denis, Sorger, Peter K, Seeley, Erin H, Navin, Nicholas, Downey, Robert J, Michor, Franziska
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Sprache:eng
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