7β-22 Dihydroxyhopane, Isolated from the Sub-Antarctic Lichen, Inhibits the Viability and Stemness in Glioma Stem Like Cells

Background: Glioma stem cells (GSCs) have been reported to contribute to tumor initiation and relapse, therapy resistance, and intra-tumoral heterogeneity of glioblastoma multiforme. Therefore, inhibiting GSCs presents a critical therapeutic tactic to suppress the aggressiveness of tumors. Methods:...

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Veröffentlicht in:	OncoTargets and therapy 2022, Vol.15, p.1375-1383
Hauptverfasser:	Kim, Hyun-Jin, Suh, Sung-Suk, Park, Jeongwon, Shin, Min-Ji, Koo, Man Hyung, Lee, Suk Jun, Jeon, Young-Jun, Lee, Seongsoo, Youn, Ui-Joung, Kim, Sung-Hak
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Annexin V Apoptosis Brain cancer Brain research Brain tumors Cancer therapies Cell culture Cell death Cell proliferation Chemotherapy Cytotoxicity Epidermal growth factor Glioblastoma Glioma Glioma cells Laboratories Lichens Original Research R&D Research & development Solvents Stem cells Western blotting
Online-Zugang:	Volltext
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