Antimicrobial use in Canadian acute-care hospitals: Findings from three national point-prevalence surveys between 2002 and 2017
The Canadian Nosocomial Infection Surveillance Program conducted point-prevalence surveys in acute-care hospitals in 2002, 2009, and 2017 to identify trends in antimicrobial use. Eligible inpatients were identified from a 24-hour period in February of each survey year. Patients were eligible (1) if...
Gespeichert in:
| Veröffentlicht in: | Infection control and hospital epidemiology 2022-11, Vol.43 (11), p.1558-1564 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1564 |
|---|---|
| container_issue | 11 |
| container_start_page | 1558 |
| container_title | Infection control and hospital epidemiology |
| container_volume | 43 |
| creator | Liang, Jennifer J. Rudnick, Wallis Mitchell, Robyn Brooks, James Bush, Kathryn Conly, John Ellison, Jennifer Frenette, Charles Johnston, Lynn Lavallée, Christian McGeer, Allison Mertz, Dominik Pelude, Linda Science, Michelle Simor, Andrew Smith, Stephanie Stagg, Paula Suh, Kathryn N. Thampi, Nisha Thirion, Daniel J.G. Vayalumkal, Joseph Wong, Alice Taylor, Geoffrey |
| description | The Canadian Nosocomial Infection Surveillance Program conducted point-prevalence surveys in acute-care hospitals in 2002, 2009, and 2017 to identify trends in antimicrobial use.
Eligible inpatients were identified from a 24-hour period in February of each survey year. Patients were eligible (1) if they were admitted for ≥48 hours or (2) if they had been admitted to the hospital within a month. Chart reviews were conducted. We calculated the prevalence of antimicrobial use as follows: patients receiving ≥1 antimicrobial during survey period per number of patients surveyed × 100%.
In each survey, 28-47 hospitals participated. In 2002, 2,460 (36.5%; 95% CI, 35.3%-37.6%) of 6,747 surveyed patients received ≥1 antimicrobial. In 2009, 3,566 (40.1%, 95% CI, 39.0%-41.1%) of 8,902 patients received ≥1 antimicrobial. In 2017, 3,936 (39.6%, 95% CI, 38.7%-40.6%) of 9,929 patients received ≥1 antimicrobial. Among patients who received ≥1 antimicrobial, penicillin use increased 36.8% between 2002 and 2017, and third-generation cephalosporin use increased from 13.9% to 18.1% (P < .0001). Between 2002 and 2017, fluoroquinolone use decreased from 25.7% to 16.3% (P < .0001) and clindamycin use decreased from 25.7% to 16.3% (P < .0001) among patients who received ≥1 antimicrobial. Aminoglycoside use decreased from 8.8% to 2.4% (P < .0001) and metronidazole use decreased from 18.1% to 9.4% (P < .0001). Carbapenem use increased from 3.9% in 2002 to 6.1% in 2009 (P < .0001) and increased by 4.8% between 2009 and 2017 (P = .60).
The prevalence of antimicrobial use increased between 2002 and 2009 and then stabilized between 2009 and 2017. These data provide important information for antimicrobial stewardship programs. |
| doi_str_mv | 10.1017/ice.2021.519 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9672830</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cupid>10_1017_ice_2021_519</cupid><sourcerecordid>2736992236</sourcerecordid><originalsourceid>FETCH-LOGICAL-c451t-983b8d1916b211fd13080545e4381d2a5b9a64aae4b72b13b083b0ea08ac480c3</originalsourceid><addsrcrecordid>eNptkc2L1DAYh4Mo7jh68ywBLx7smI8mTTwsLIOrwoIXBW_hTfvOTJY2rUk7sif_dbPsuH7gKYE8efLm9yPkOWcbznjzJrS4EUzwjeL2AVlxpWyljawfkhUz1lZGyK9n5EnO14yxxlr-mJxJJWqrdL0iPy7iHIbQptEH6OmSkYZItxChCxAptMuMVQsJ6WHMU5ihz2_pZYhdiPtMd2kc6HxIiDTCHMZYFNMY4lxNCY_QY2yR5iUd8SZTj_N3xEgFY4JC7MqGN0_Jo11x4rPTuiZfLt993n6orj69_7i9uKraWvG5skZ603HLtRec7zoumWGqVlhLwzsBylvQNQDWvhGeS8_KBYbADLS1Ya1ck_M777T4AbsW45ygd1MKA6QbN0Jwf5_EcHD78eisboSRrAhenQRp_LZgnt0Qcot9DxHHJTuhpTZGqxL9mrz8B70el1SyKVQjtbVCSF2o13dUyT7nhLv7YThzt8260qy7bdaVZgv-4s8P3MO_qizA5uSDwafQ7fH3s_81_gQZVq6e</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2736992236</pqid></control><display><type>article</type><title>Antimicrobial use in Canadian acute-care hospitals: Findings from three national point-prevalence surveys between 2002 and 2017</title><source>Cambridge Journals</source><source>ProQuest Central</source><creator>Liang, Jennifer J. ; Rudnick, Wallis ; Mitchell, Robyn ; Brooks, James ; Bush, Kathryn ; Conly, John ; Ellison, Jennifer ; Frenette, Charles ; Johnston, Lynn ; Lavallée, Christian ; McGeer, Allison ; Mertz, Dominik ; Pelude, Linda ; Science, Michelle ; Simor, Andrew ; Smith, Stephanie ; Stagg, Paula ; Suh, Kathryn N. ; Thampi, Nisha ; Thirion, Daniel J.G. ; Vayalumkal, Joseph ; Wong, Alice ; Taylor, Geoffrey</creator><creatorcontrib>Liang, Jennifer J. ; Rudnick, Wallis ; Mitchell, Robyn ; Brooks, James ; Bush, Kathryn ; Conly, John ; Ellison, Jennifer ; Frenette, Charles ; Johnston, Lynn ; Lavallée, Christian ; McGeer, Allison ; Mertz, Dominik ; Pelude, Linda ; Science, Michelle ; Simor, Andrew ; Smith, Stephanie ; Stagg, Paula ; Suh, Kathryn N. ; Thampi, Nisha ; Thirion, Daniel J.G. ; Vayalumkal, Joseph ; Wong, Alice ; Taylor, Geoffrey ; Canadian Nosocomial Infection Surveillance Program ; for the Canadian Nosocomial Infection Surveillance Program</creatorcontrib><description><![CDATA[The Canadian Nosocomial Infection Surveillance Program conducted point-prevalence surveys in acute-care hospitals in 2002, 2009, and 2017 to identify trends in antimicrobial use.
Eligible inpatients were identified from a 24-hour period in February of each survey year. Patients were eligible (1) if they were admitted for ≥48 hours or (2) if they had been admitted to the hospital within a month. Chart reviews were conducted. We calculated the prevalence of antimicrobial use as follows: patients receiving ≥1 antimicrobial during survey period per number of patients surveyed × 100%.
In each survey, 28-47 hospitals participated. In 2002, 2,460 (36.5%; 95% CI, 35.3%-37.6%) of 6,747 surveyed patients received ≥1 antimicrobial. In 2009, 3,566 (40.1%, 95% CI, 39.0%-41.1%) of 8,902 patients received ≥1 antimicrobial. In 2017, 3,936 (39.6%, 95% CI, 38.7%-40.6%) of 9,929 patients received ≥1 antimicrobial. Among patients who received ≥1 antimicrobial, penicillin use increased 36.8% between 2002 and 2017, and third-generation cephalosporin use increased from 13.9% to 18.1% (P < .0001). Between 2002 and 2017, fluoroquinolone use decreased from 25.7% to 16.3% (P < .0001) and clindamycin use decreased from 25.7% to 16.3% (P < .0001) among patients who received ≥1 antimicrobial. Aminoglycoside use decreased from 8.8% to 2.4% (P < .0001) and metronidazole use decreased from 18.1% to 9.4% (P < .0001). Carbapenem use increased from 3.9% in 2002 to 6.1% in 2009 (P < .0001) and increased by 4.8% between 2009 and 2017 (P = .60).
The prevalence of antimicrobial use increased between 2002 and 2009 and then stabilized between 2009 and 2017. These data provide important information for antimicrobial stewardship programs.]]></description><identifier>ISSN: 0899-823X</identifier><identifier>EISSN: 1559-6834</identifier><identifier>DOI: 10.1017/ice.2021.519</identifier><identifier>PMID: 35249564</identifier><language>eng</language><publisher>New York, USA: Cambridge University Press</publisher><subject>Antibiotics ; Antimicrobial agents ; Confidence intervals ; Drug resistance ; Hospitals ; Nosocomial infection ; Nosocomial infections ; Original ; Original Article ; Patients ; Penicillin ; Polls & surveys ; Trends</subject><ispartof>Infection control and hospital epidemiology, 2022-11, Vol.43 (11), p.1558-1564</ispartof><rights>The Author(s), 2022. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America</rights><rights>The Author(s), 2022. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America. This work is licensed under the Creative Commons Attribution License This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited. (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2022 2022 The Author(s)</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c451t-983b8d1916b211fd13080545e4381d2a5b9a64aae4b72b13b083b0ea08ac480c3</citedby><cites>FETCH-LOGICAL-c451t-983b8d1916b211fd13080545e4381d2a5b9a64aae4b72b13b083b0ea08ac480c3</cites><orcidid>0000-0003-0208-6277 ; 0000-0001-5760-0136 ; 0000-0003-3457-4216 ; 0000-0003-2011-0541 ; 0000-0001-5647-6137 ; 0000-0003-4337-1613 ; 0000-0002-2474-2186 ; 0000-0001-6278-9519</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2736992236/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2736992236?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>164,230,314,776,780,881,21367,27901,27902,33721,33722,43781,55603,74273</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35249564$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liang, Jennifer J.</creatorcontrib><creatorcontrib>Rudnick, Wallis</creatorcontrib><creatorcontrib>Mitchell, Robyn</creatorcontrib><creatorcontrib>Brooks, James</creatorcontrib><creatorcontrib>Bush, Kathryn</creatorcontrib><creatorcontrib>Conly, John</creatorcontrib><creatorcontrib>Ellison, Jennifer</creatorcontrib><creatorcontrib>Frenette, Charles</creatorcontrib><creatorcontrib>Johnston, Lynn</creatorcontrib><creatorcontrib>Lavallée, Christian</creatorcontrib><creatorcontrib>McGeer, Allison</creatorcontrib><creatorcontrib>Mertz, Dominik</creatorcontrib><creatorcontrib>Pelude, Linda</creatorcontrib><creatorcontrib>Science, Michelle</creatorcontrib><creatorcontrib>Simor, Andrew</creatorcontrib><creatorcontrib>Smith, Stephanie</creatorcontrib><creatorcontrib>Stagg, Paula</creatorcontrib><creatorcontrib>Suh, Kathryn N.</creatorcontrib><creatorcontrib>Thampi, Nisha</creatorcontrib><creatorcontrib>Thirion, Daniel J.G.</creatorcontrib><creatorcontrib>Vayalumkal, Joseph</creatorcontrib><creatorcontrib>Wong, Alice</creatorcontrib><creatorcontrib>Taylor, Geoffrey</creatorcontrib><creatorcontrib>Canadian Nosocomial Infection Surveillance Program</creatorcontrib><creatorcontrib>for the Canadian Nosocomial Infection Surveillance Program</creatorcontrib><title>Antimicrobial use in Canadian acute-care hospitals: Findings from three national point-prevalence surveys between 2002 and 2017</title><title>Infection control and hospital epidemiology</title><addtitle>Infect. Control Hosp. Epidemiol</addtitle><description><![CDATA[The Canadian Nosocomial Infection Surveillance Program conducted point-prevalence surveys in acute-care hospitals in 2002, 2009, and 2017 to identify trends in antimicrobial use.
Eligible inpatients were identified from a 24-hour period in February of each survey year. Patients were eligible (1) if they were admitted for ≥48 hours or (2) if they had been admitted to the hospital within a month. Chart reviews were conducted. We calculated the prevalence of antimicrobial use as follows: patients receiving ≥1 antimicrobial during survey period per number of patients surveyed × 100%.
In each survey, 28-47 hospitals participated. In 2002, 2,460 (36.5%; 95% CI, 35.3%-37.6%) of 6,747 surveyed patients received ≥1 antimicrobial. In 2009, 3,566 (40.1%, 95% CI, 39.0%-41.1%) of 8,902 patients received ≥1 antimicrobial. In 2017, 3,936 (39.6%, 95% CI, 38.7%-40.6%) of 9,929 patients received ≥1 antimicrobial. Among patients who received ≥1 antimicrobial, penicillin use increased 36.8% between 2002 and 2017, and third-generation cephalosporin use increased from 13.9% to 18.1% (P < .0001). Between 2002 and 2017, fluoroquinolone use decreased from 25.7% to 16.3% (P < .0001) and clindamycin use decreased from 25.7% to 16.3% (P < .0001) among patients who received ≥1 antimicrobial. Aminoglycoside use decreased from 8.8% to 2.4% (P < .0001) and metronidazole use decreased from 18.1% to 9.4% (P < .0001). Carbapenem use increased from 3.9% in 2002 to 6.1% in 2009 (P < .0001) and increased by 4.8% between 2009 and 2017 (P = .60).
The prevalence of antimicrobial use increased between 2002 and 2009 and then stabilized between 2009 and 2017. These data provide important information for antimicrobial stewardship programs.]]></description><subject>Antibiotics</subject><subject>Antimicrobial agents</subject><subject>Confidence intervals</subject><subject>Drug resistance</subject><subject>Hospitals</subject><subject>Nosocomial infection</subject><subject>Nosocomial infections</subject><subject>Original</subject><subject>Original Article</subject><subject>Patients</subject><subject>Penicillin</subject><subject>Polls & surveys</subject><subject>Trends</subject><issn>0899-823X</issn><issn>1559-6834</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>IKXGN</sourceid><sourceid>BENPR</sourceid><recordid>eNptkc2L1DAYh4Mo7jh68ywBLx7smI8mTTwsLIOrwoIXBW_hTfvOTJY2rUk7sif_dbPsuH7gKYE8efLm9yPkOWcbznjzJrS4EUzwjeL2AVlxpWyljawfkhUz1lZGyK9n5EnO14yxxlr-mJxJJWqrdL0iPy7iHIbQptEH6OmSkYZItxChCxAptMuMVQsJ6WHMU5ihz2_pZYhdiPtMd2kc6HxIiDTCHMZYFNMY4lxNCY_QY2yR5iUd8SZTj_N3xEgFY4JC7MqGN0_Jo11x4rPTuiZfLt993n6orj69_7i9uKraWvG5skZ603HLtRec7zoumWGqVlhLwzsBylvQNQDWvhGeS8_KBYbADLS1Ya1ck_M777T4AbsW45ygd1MKA6QbN0Jwf5_EcHD78eisboSRrAhenQRp_LZgnt0Qcot9DxHHJTuhpTZGqxL9mrz8B70el1SyKVQjtbVCSF2o13dUyT7nhLv7YThzt8260qy7bdaVZgv-4s8P3MO_qizA5uSDwafQ7fH3s_81_gQZVq6e</recordid><startdate>20221101</startdate><enddate>20221101</enddate><creator>Liang, Jennifer J.</creator><creator>Rudnick, Wallis</creator><creator>Mitchell, Robyn</creator><creator>Brooks, James</creator><creator>Bush, Kathryn</creator><creator>Conly, John</creator><creator>Ellison, Jennifer</creator><creator>Frenette, Charles</creator><creator>Johnston, Lynn</creator><creator>Lavallée, Christian</creator><creator>McGeer, Allison</creator><creator>Mertz, Dominik</creator><creator>Pelude, Linda</creator><creator>Science, Michelle</creator><creator>Simor, Andrew</creator><creator>Smith, Stephanie</creator><creator>Stagg, Paula</creator><creator>Suh, Kathryn N.</creator><creator>Thampi, Nisha</creator><creator>Thirion, Daniel J.G.</creator><creator>Vayalumkal, Joseph</creator><creator>Wong, Alice</creator><creator>Taylor, Geoffrey</creator><general>Cambridge University Press</general><scope>IKXGN</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>S0X</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-0208-6277</orcidid><orcidid>https://orcid.org/0000-0001-5760-0136</orcidid><orcidid>https://orcid.org/0000-0003-3457-4216</orcidid><orcidid>https://orcid.org/0000-0003-2011-0541</orcidid><orcidid>https://orcid.org/0000-0001-5647-6137</orcidid><orcidid>https://orcid.org/0000-0003-4337-1613</orcidid><orcidid>https://orcid.org/0000-0002-2474-2186</orcidid><orcidid>https://orcid.org/0000-0001-6278-9519</orcidid></search><sort><creationdate>20221101</creationdate><title>Antimicrobial use in Canadian acute-care hospitals: Findings from three national point-prevalence surveys between 2002 and 2017</title><author>Liang, Jennifer J. ; Rudnick, Wallis ; Mitchell, Robyn ; Brooks, James ; Bush, Kathryn ; Conly, John ; Ellison, Jennifer ; Frenette, Charles ; Johnston, Lynn ; Lavallée, Christian ; McGeer, Allison ; Mertz, Dominik ; Pelude, Linda ; Science, Michelle ; Simor, Andrew ; Smith, Stephanie ; Stagg, Paula ; Suh, Kathryn N. ; Thampi, Nisha ; Thirion, Daniel J.G. ; Vayalumkal, Joseph ; Wong, Alice ; Taylor, Geoffrey</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c451t-983b8d1916b211fd13080545e4381d2a5b9a64aae4b72b13b083b0ea08ac480c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Antibiotics</topic><topic>Antimicrobial agents</topic><topic>Confidence intervals</topic><topic>Drug resistance</topic><topic>Hospitals</topic><topic>Nosocomial infection</topic><topic>Nosocomial infections</topic><topic>Original</topic><topic>Original Article</topic><topic>Patients</topic><topic>Penicillin</topic><topic>Polls & surveys</topic><topic>Trends</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liang, Jennifer J.</creatorcontrib><creatorcontrib>Rudnick, Wallis</creatorcontrib><creatorcontrib>Mitchell, Robyn</creatorcontrib><creatorcontrib>Brooks, James</creatorcontrib><creatorcontrib>Bush, Kathryn</creatorcontrib><creatorcontrib>Conly, John</creatorcontrib><creatorcontrib>Ellison, Jennifer</creatorcontrib><creatorcontrib>Frenette, Charles</creatorcontrib><creatorcontrib>Johnston, Lynn</creatorcontrib><creatorcontrib>Lavallée, Christian</creatorcontrib><creatorcontrib>McGeer, Allison</creatorcontrib><creatorcontrib>Mertz, Dominik</creatorcontrib><creatorcontrib>Pelude, Linda</creatorcontrib><creatorcontrib>Science, Michelle</creatorcontrib><creatorcontrib>Simor, Andrew</creatorcontrib><creatorcontrib>Smith, Stephanie</creatorcontrib><creatorcontrib>Stagg, Paula</creatorcontrib><creatorcontrib>Suh, Kathryn N.</creatorcontrib><creatorcontrib>Thampi, Nisha</creatorcontrib><creatorcontrib>Thirion, Daniel J.G.</creatorcontrib><creatorcontrib>Vayalumkal, Joseph</creatorcontrib><creatorcontrib>Wong, Alice</creatorcontrib><creatorcontrib>Taylor, Geoffrey</creatorcontrib><creatorcontrib>Canadian Nosocomial Infection Surveillance Program</creatorcontrib><creatorcontrib>for the Canadian Nosocomial Infection Surveillance Program</creatorcontrib><collection>Cambridge Journals Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>ProQuest Health & Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Infection control and hospital epidemiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liang, Jennifer J.</au><au>Rudnick, Wallis</au><au>Mitchell, Robyn</au><au>Brooks, James</au><au>Bush, Kathryn</au><au>Conly, John</au><au>Ellison, Jennifer</au><au>Frenette, Charles</au><au>Johnston, Lynn</au><au>Lavallée, Christian</au><au>McGeer, Allison</au><au>Mertz, Dominik</au><au>Pelude, Linda</au><au>Science, Michelle</au><au>Simor, Andrew</au><au>Smith, Stephanie</au><au>Stagg, Paula</au><au>Suh, Kathryn N.</au><au>Thampi, Nisha</au><au>Thirion, Daniel J.G.</au><au>Vayalumkal, Joseph</au><au>Wong, Alice</au><au>Taylor, Geoffrey</au><aucorp>Canadian Nosocomial Infection Surveillance Program</aucorp><aucorp>for the Canadian Nosocomial Infection Surveillance Program</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antimicrobial use in Canadian acute-care hospitals: Findings from three national point-prevalence surveys between 2002 and 2017</atitle><jtitle>Infection control and hospital epidemiology</jtitle><addtitle>Infect. Control Hosp. Epidemiol</addtitle><date>2022-11-01</date><risdate>2022</risdate><volume>43</volume><issue>11</issue><spage>1558</spage><epage>1564</epage><pages>1558-1564</pages><issn>0899-823X</issn><eissn>1559-6834</eissn><abstract><![CDATA[The Canadian Nosocomial Infection Surveillance Program conducted point-prevalence surveys in acute-care hospitals in 2002, 2009, and 2017 to identify trends in antimicrobial use.
Eligible inpatients were identified from a 24-hour period in February of each survey year. Patients were eligible (1) if they were admitted for ≥48 hours or (2) if they had been admitted to the hospital within a month. Chart reviews were conducted. We calculated the prevalence of antimicrobial use as follows: patients receiving ≥1 antimicrobial during survey period per number of patients surveyed × 100%.
In each survey, 28-47 hospitals participated. In 2002, 2,460 (36.5%; 95% CI, 35.3%-37.6%) of 6,747 surveyed patients received ≥1 antimicrobial. In 2009, 3,566 (40.1%, 95% CI, 39.0%-41.1%) of 8,902 patients received ≥1 antimicrobial. In 2017, 3,936 (39.6%, 95% CI, 38.7%-40.6%) of 9,929 patients received ≥1 antimicrobial. Among patients who received ≥1 antimicrobial, penicillin use increased 36.8% between 2002 and 2017, and third-generation cephalosporin use increased from 13.9% to 18.1% (P < .0001). Between 2002 and 2017, fluoroquinolone use decreased from 25.7% to 16.3% (P < .0001) and clindamycin use decreased from 25.7% to 16.3% (P < .0001) among patients who received ≥1 antimicrobial. Aminoglycoside use decreased from 8.8% to 2.4% (P < .0001) and metronidazole use decreased from 18.1% to 9.4% (P < .0001). Carbapenem use increased from 3.9% in 2002 to 6.1% in 2009 (P < .0001) and increased by 4.8% between 2009 and 2017 (P = .60).
The prevalence of antimicrobial use increased between 2002 and 2009 and then stabilized between 2009 and 2017. These data provide important information for antimicrobial stewardship programs.]]></abstract><cop>New York, USA</cop><pub>Cambridge University Press</pub><pmid>35249564</pmid><doi>10.1017/ice.2021.519</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0003-0208-6277</orcidid><orcidid>https://orcid.org/0000-0001-5760-0136</orcidid><orcidid>https://orcid.org/0000-0003-3457-4216</orcidid><orcidid>https://orcid.org/0000-0003-2011-0541</orcidid><orcidid>https://orcid.org/0000-0001-5647-6137</orcidid><orcidid>https://orcid.org/0000-0003-4337-1613</orcidid><orcidid>https://orcid.org/0000-0002-2474-2186</orcidid><orcidid>https://orcid.org/0000-0001-6278-9519</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0899-823X |
| ispartof | Infection control and hospital epidemiology, 2022-11, Vol.43 (11), p.1558-1564 |
| issn | 0899-823X 1559-6834 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9672830 |
| source | Cambridge Journals; ProQuest Central |
| subjects | Antibiotics Antimicrobial agents Confidence intervals Drug resistance Hospitals Nosocomial infection Nosocomial infections Original Original Article Patients Penicillin Polls & surveys Trends |
| title | Antimicrobial use in Canadian acute-care hospitals: Findings from three national point-prevalence surveys between 2002 and 2017 |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-19T10%3A07%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Antimicrobial%20use%20in%20Canadian%20acute-care%20hospitals:%20Findings%20from%20three%20national%20point-prevalence%20surveys%20between%202002%20and%202017&rft.jtitle=Infection%20control%20and%20hospital%20epidemiology&rft.au=Liang,%20Jennifer%20J.&rft.aucorp=Canadian%20Nosocomial%20Infection%20Surveillance%20Program&rft.date=2022-11-01&rft.volume=43&rft.issue=11&rft.spage=1558&rft.epage=1564&rft.pages=1558-1564&rft.issn=0899-823X&rft.eissn=1559-6834&rft_id=info:doi/10.1017/ice.2021.519&rft_dat=%3Cproquest_pubme%3E2736992236%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2736992236&rft_id=info:pmid/35249564&rft_cupid=10_1017_ice_2021_519&rfr_iscdi=true |