The value of the sacroiliac joint area as a new morphological parameter of ankylosing spondylitis
A narrowed sacroiliac joint (SIJ) space has been considered to be a major morphologic parameter of ankylosing spondylitis (AS). Previous studies revealed that the sacroiliac joint thickness (SIJT) correlated with AS in patients. However, irregular narrowing is different from thickness. Thus, we devi...
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| Veröffentlicht in: | Medicine (Baltimore) 2022-11, Vol.101 (45), p.e31723-e31723 |
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| creator | Bang, Yun-Sic Hwang, He Won Bae, Hanwool Choi, Young-Soon Lim, Youngsu Yi, Jungmin Kim, Hyunhae Su, Min-Ying Kim, Young Uk |
| description | A narrowed sacroiliac joint (SIJ) space has been considered to be a major morphologic parameter of ankylosing spondylitis (AS). Previous studies revealed that the sacroiliac joint thickness (SIJT) correlated with AS in patients. However, irregular narrowing is different from thickness. Thus, we devised a method using the sacroiliac joint cross-sectional area (SIJA) as a new morphological parameter for use in evaluating AS. We hypothesized that the SIJA is a key morphologic parameter in diagnosing AS. SIJ samples were collected from 107 patients with AS, and from 85 control subjects who underwent SIJ-view X-rays that revealed no evidence of AS. We measured the SIJT and SIJA at the SIJ margin on X-rays using our picture archiving and communications system. The SIJT was measured at the narrowest point between the sacrum and the ilium. The SIJA was measured as the entire cross-sectional joint space area of the SIJ in the X-ray images. The average SIJT was 3.09 ± 0.61 mm in the control group, and 1.59 ± 0.52 mm in the AS group. The average SIJA was 166.74 ± 39.98 mm
2
in the control group, and 68.65 ± 24.11 mm
2
in the AS group. AS patients had significantly lower SIJT (
P
|
| doi_str_mv | 10.1097/MD.0000000000031723 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9666185</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2738190893</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4001-67d37e8f5da8e94f3903b9037c9d47092c2895e2cebd0b8fd6066a97735966e43</originalsourceid><addsrcrecordid>eNpdUU1v1DAQtRCIlsIvQEI-cknxR2LHFyTUlg-pFZdytmadycatEwc76Wr_PS5bSmGkkT32e8_jeYS85eyUM6M_XJ2fsr8huRbyGTnmjVRVY1T9_Mn-iLzK-YYxLrWoX5IjqaTRstHHBK4HpHcQVqSxp0spMrgUffDg6E3000IhIVDIFOiEOzrGNA8xxK13EOgMCUZcMN2zYbrdh5j9tKV5jlO3D37x-TV50UPI-OZhPSE_Pl9cn32tLr9_-Xb26bJydWmsUrqTGtu-6aBFU_fSMLkpqZ3pas2McKI1DQqHm45t2r5TTCkwunzDKIW1PCEfD7rzuhmxczgtCYKdkx8h7W0Eb_-9mfxgt_HOFrribVME3j8IpPhzxbzY0WeHIcCEcc1WaNlyw1ojC1QeoGVUOSfsH5_hzN6bY6_O7f_mFNa7px0-cv64UQD1AbCLocw034Z1h8kOCGEZfus12ohKMCF4CVaVk5rLX3rymzs</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2738190893</pqid></control><display><type>article</type><title>The value of the sacroiliac joint area as a new morphological parameter of ankylosing spondylitis</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Wolters Kluwer Open Health</source><source>IngentaConnect Free/Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Bang, Yun-Sic ; Hwang, He Won ; Bae, Hanwool ; Choi, Young-Soon ; Lim, Youngsu ; Yi, Jungmin ; Kim, Hyunhae ; Su, Min-Ying ; Kim, Young Uk</creator><creatorcontrib>Bang, Yun-Sic ; Hwang, He Won ; Bae, Hanwool ; Choi, Young-Soon ; Lim, Youngsu ; Yi, Jungmin ; Kim, Hyunhae ; Su, Min-Ying ; Kim, Young Uk</creatorcontrib><description>A narrowed sacroiliac joint (SIJ) space has been considered to be a major morphologic parameter of ankylosing spondylitis (AS). Previous studies revealed that the sacroiliac joint thickness (SIJT) correlated with AS in patients. However, irregular narrowing is different from thickness. Thus, we devised a method using the sacroiliac joint cross-sectional area (SIJA) as a new morphological parameter for use in evaluating AS. We hypothesized that the SIJA is a key morphologic parameter in diagnosing AS. SIJ samples were collected from 107 patients with AS, and from 85 control subjects who underwent SIJ-view X-rays that revealed no evidence of AS. We measured the SIJT and SIJA at the SIJ margin on X-rays using our picture archiving and communications system. The SIJT was measured at the narrowest point between the sacrum and the ilium. The SIJA was measured as the entire cross-sectional joint space area of the SIJ in the X-ray images. The average SIJT was 3.09 ± 0.61 mm in the control group, and 1.59 ± 0.52 mm in the AS group. The average SIJA was 166.74 ± 39.98 mm
2
in the control group, and 68.65 ± 24.11 mm
2
in the AS group. AS patients had significantly lower SIJT (
P
< .001) and SIJA (
P
< .001) than the control subjects. Receiver operating characteristics curve analysis showed that the best cutoff point for the SIJT was 2.33 mm, with 92.5% sensitivity, 94.1% specificity, and an area under the curve of 0.97 (95% confidence interval0.95–0.99). The optimal cutoff point for the SIJA was 106.19 mm
2
, with 93.5% sensitivity, 95.3% specificity, and an area under the curve of 0.98 (95% confidence interval0.97–1.00). Although the SIJT and SIJA were both significantly associated with AS, the SIJA parameter was a more sensitive measurement. We concluded that the SIJA is an easy-to-use, fast, cheap, and useful new morphological parameter for predicting AS.</description><identifier>ISSN: 1536-5964</identifier><identifier>ISSN: 0025-7974</identifier><identifier>EISSN: 1536-5964</identifier><identifier>DOI: 10.1097/MD.0000000000031723</identifier><identifier>PMID: 36397357</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins</publisher><subject>Humans ; Ilium ; Observational Study ; Sacroiliac Joint - diagnostic imaging ; Sacrum ; Spondylitis, Ankylosing - diagnostic imaging</subject><ispartof>Medicine (Baltimore), 2022-11, Vol.101 (45), p.e31723-e31723</ispartof><rights>Lippincott Williams & Wilkins</rights><rights>Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.</rights><rights>Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c4001-67d37e8f5da8e94f3903b9037c9d47092c2895e2cebd0b8fd6066a97735966e43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666185/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666185/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,861,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36397357$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bang, Yun-Sic</creatorcontrib><creatorcontrib>Hwang, He Won</creatorcontrib><creatorcontrib>Bae, Hanwool</creatorcontrib><creatorcontrib>Choi, Young-Soon</creatorcontrib><creatorcontrib>Lim, Youngsu</creatorcontrib><creatorcontrib>Yi, Jungmin</creatorcontrib><creatorcontrib>Kim, Hyunhae</creatorcontrib><creatorcontrib>Su, Min-Ying</creatorcontrib><creatorcontrib>Kim, Young Uk</creatorcontrib><title>The value of the sacroiliac joint area as a new morphological parameter of ankylosing spondylitis</title><title>Medicine (Baltimore)</title><addtitle>Medicine (Baltimore)</addtitle><description>A narrowed sacroiliac joint (SIJ) space has been considered to be a major morphologic parameter of ankylosing spondylitis (AS). Previous studies revealed that the sacroiliac joint thickness (SIJT) correlated with AS in patients. However, irregular narrowing is different from thickness. Thus, we devised a method using the sacroiliac joint cross-sectional area (SIJA) as a new morphological parameter for use in evaluating AS. We hypothesized that the SIJA is a key morphologic parameter in diagnosing AS. SIJ samples were collected from 107 patients with AS, and from 85 control subjects who underwent SIJ-view X-rays that revealed no evidence of AS. We measured the SIJT and SIJA at the SIJ margin on X-rays using our picture archiving and communications system. The SIJT was measured at the narrowest point between the sacrum and the ilium. The SIJA was measured as the entire cross-sectional joint space area of the SIJ in the X-ray images. The average SIJT was 3.09 ± 0.61 mm in the control group, and 1.59 ± 0.52 mm in the AS group. The average SIJA was 166.74 ± 39.98 mm
2
in the control group, and 68.65 ± 24.11 mm
2
in the AS group. AS patients had significantly lower SIJT (
P
< .001) and SIJA (
P
< .001) than the control subjects. Receiver operating characteristics curve analysis showed that the best cutoff point for the SIJT was 2.33 mm, with 92.5% sensitivity, 94.1% specificity, and an area under the curve of 0.97 (95% confidence interval0.95–0.99). The optimal cutoff point for the SIJA was 106.19 mm
2
, with 93.5% sensitivity, 95.3% specificity, and an area under the curve of 0.98 (95% confidence interval0.97–1.00). Although the SIJT and SIJA were both significantly associated with AS, the SIJA parameter was a more sensitive measurement. We concluded that the SIJA is an easy-to-use, fast, cheap, and useful new morphological parameter for predicting AS.</description><subject>Humans</subject><subject>Ilium</subject><subject>Observational Study</subject><subject>Sacroiliac Joint - diagnostic imaging</subject><subject>Sacrum</subject><subject>Spondylitis, Ankylosing - diagnostic imaging</subject><issn>1536-5964</issn><issn>0025-7974</issn><issn>1536-5964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdUU1v1DAQtRCIlsIvQEI-cknxR2LHFyTUlg-pFZdytmadycatEwc76Wr_PS5bSmGkkT32e8_jeYS85eyUM6M_XJ2fsr8huRbyGTnmjVRVY1T9_Mn-iLzK-YYxLrWoX5IjqaTRstHHBK4HpHcQVqSxp0spMrgUffDg6E3000IhIVDIFOiEOzrGNA8xxK13EOgMCUZcMN2zYbrdh5j9tKV5jlO3D37x-TV50UPI-OZhPSE_Pl9cn32tLr9_-Xb26bJydWmsUrqTGtu-6aBFU_fSMLkpqZ3pas2McKI1DQqHm45t2r5TTCkwunzDKIW1PCEfD7rzuhmxczgtCYKdkx8h7W0Eb_-9mfxgt_HOFrribVME3j8IpPhzxbzY0WeHIcCEcc1WaNlyw1ojC1QeoGVUOSfsH5_hzN6bY6_O7f_mFNa7px0-cv64UQD1AbCLocw034Z1h8kOCGEZfus12ohKMCF4CVaVk5rLX3rymzs</recordid><startdate>20221111</startdate><enddate>20221111</enddate><creator>Bang, Yun-Sic</creator><creator>Hwang, He Won</creator><creator>Bae, Hanwool</creator><creator>Choi, Young-Soon</creator><creator>Lim, Youngsu</creator><creator>Yi, Jungmin</creator><creator>Kim, Hyunhae</creator><creator>Su, Min-Ying</creator><creator>Kim, Young Uk</creator><general>Lippincott Williams & Wilkins</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20221111</creationdate><title>The value of the sacroiliac joint area as a new morphological parameter of ankylosing spondylitis</title><author>Bang, Yun-Sic ; Hwang, He Won ; Bae, Hanwool ; Choi, Young-Soon ; Lim, Youngsu ; Yi, Jungmin ; Kim, Hyunhae ; Su, Min-Ying ; Kim, Young Uk</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4001-67d37e8f5da8e94f3903b9037c9d47092c2895e2cebd0b8fd6066a97735966e43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Humans</topic><topic>Ilium</topic><topic>Observational Study</topic><topic>Sacroiliac Joint - diagnostic imaging</topic><topic>Sacrum</topic><topic>Spondylitis, Ankylosing - diagnostic imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bang, Yun-Sic</creatorcontrib><creatorcontrib>Hwang, He Won</creatorcontrib><creatorcontrib>Bae, Hanwool</creatorcontrib><creatorcontrib>Choi, Young-Soon</creatorcontrib><creatorcontrib>Lim, Youngsu</creatorcontrib><creatorcontrib>Yi, Jungmin</creatorcontrib><creatorcontrib>Kim, Hyunhae</creatorcontrib><creatorcontrib>Su, Min-Ying</creatorcontrib><creatorcontrib>Kim, Young Uk</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicine (Baltimore)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bang, Yun-Sic</au><au>Hwang, He Won</au><au>Bae, Hanwool</au><au>Choi, Young-Soon</au><au>Lim, Youngsu</au><au>Yi, Jungmin</au><au>Kim, Hyunhae</au><au>Su, Min-Ying</au><au>Kim, Young Uk</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The value of the sacroiliac joint area as a new morphological parameter of ankylosing spondylitis</atitle><jtitle>Medicine (Baltimore)</jtitle><addtitle>Medicine (Baltimore)</addtitle><date>2022-11-11</date><risdate>2022</risdate><volume>101</volume><issue>45</issue><spage>e31723</spage><epage>e31723</epage><pages>e31723-e31723</pages><issn>1536-5964</issn><issn>0025-7974</issn><eissn>1536-5964</eissn><abstract>A narrowed sacroiliac joint (SIJ) space has been considered to be a major morphologic parameter of ankylosing spondylitis (AS). Previous studies revealed that the sacroiliac joint thickness (SIJT) correlated with AS in patients. However, irregular narrowing is different from thickness. Thus, we devised a method using the sacroiliac joint cross-sectional area (SIJA) as a new morphological parameter for use in evaluating AS. We hypothesized that the SIJA is a key morphologic parameter in diagnosing AS. SIJ samples were collected from 107 patients with AS, and from 85 control subjects who underwent SIJ-view X-rays that revealed no evidence of AS. We measured the SIJT and SIJA at the SIJ margin on X-rays using our picture archiving and communications system. The SIJT was measured at the narrowest point between the sacrum and the ilium. The SIJA was measured as the entire cross-sectional joint space area of the SIJ in the X-ray images. The average SIJT was 3.09 ± 0.61 mm in the control group, and 1.59 ± 0.52 mm in the AS group. The average SIJA was 166.74 ± 39.98 mm
2
in the control group, and 68.65 ± 24.11 mm
2
in the AS group. AS patients had significantly lower SIJT (
P
< .001) and SIJA (
P
< .001) than the control subjects. Receiver operating characteristics curve analysis showed that the best cutoff point for the SIJT was 2.33 mm, with 92.5% sensitivity, 94.1% specificity, and an area under the curve of 0.97 (95% confidence interval0.95–0.99). The optimal cutoff point for the SIJA was 106.19 mm
2
, with 93.5% sensitivity, 95.3% specificity, and an area under the curve of 0.98 (95% confidence interval0.97–1.00). Although the SIJT and SIJA were both significantly associated with AS, the SIJA parameter was a more sensitive measurement. We concluded that the SIJA is an easy-to-use, fast, cheap, and useful new morphological parameter for predicting AS.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins</pub><pmid>36397357</pmid><doi>10.1097/MD.0000000000031723</doi><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; Wolters Kluwer Open Health; IngentaConnect Free/Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Humans Ilium Observational Study Sacroiliac Joint - diagnostic imaging Sacrum Spondylitis, Ankylosing - diagnostic imaging |
| title | The value of the sacroiliac joint area as a new morphological parameter of ankylosing spondylitis |
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