Hypusinated eIF5A Promotes Ribosomal Frameshifting during Decoding of ODC Antizyme mRNA in Saccharomyces cerevisiae

Polyamines are essential biogenic poly-cations with important roles in many cellular processes and diseases such as cancer. A rate-limiting step early in the biosynthesis of polyamines is the conversion of ornithine to putrescine by the homodimeric enzyme ornithine decarboxylase (ODC). In a conserve...

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Veröffentlicht in:	International journal of molecular sciences 2022-11, Vol.23 (21), p.12972
Hauptverfasser:	Halwas, Kai, Döring, Lennard-Maximilian, Oehlert, Franziska Valentina, Dohmen, R. Jürgen
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Autophagy Binding Biosynthesis Cancer Cations Conditional mutant Depletion Dihydrofolate reductase Fungi mRNA Ornithine decarboxylase Polyamines Polypeptides Proteasomes Proteins Putrescine Ribosomes Saccharomyces cerevisiae Transfer RNA Translation Translation termination Ubiquitin Yeast
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