Indolepropionic Acid, a Gut Bacteria-Produced Tryptophan Metabolite and the Risk of Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease

An intricate relationship between gut microbiota, diet, and the human body has recently been extensively investigated. Gut microbiota and gut-derived metabolites, especially, tryptophan derivatives, modulate metabolic and immune functions in health and disease. One of the tryptophan derivatives, ind...

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Veröffentlicht in:	Nutrients 2022-11, Vol.14 (21), p.4695
Hauptverfasser:	Sehgal, Ratika, de Mello, Vanessa D, Männistö, Ville, Lindström, Jaana, Tuomilehto, Jaakko, Pihlajamäki, Jussi, Uusitupa, Matti
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Amino acids Bacteria Care and treatment Chronic illnesses Development and progression Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diet Dietary fiber Disease prevention Fatty acids Fatty liver Fibrosis Gastrointestinal surgery Genetic diversity Genetic variance Glucose Glucose metabolism Health aspects Health maintenance organizations Health risks Inflammation Inflammatory bowel disease Insulin resistance Intestinal microflora Liver Liver diseases Metabolic disorders Metabolites Microbiota Microbiota (Symbiotic organisms) Obesity Permeability Physiological aspects Phytosterols Prediabetic state Propionic acid Proteins Review Risk factors Tryptophan Tryptophan metabolism Type 2 diabetes
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